English
Related papers

Related papers: Functional characteristics of a double positive fe…

200 papers

The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates. Recent experiments,…

Cell Behavior · Quantitative Biology 2024-12-24 Pedrom Zadeh , Brian A. Camley

We investigate the influence of intrinsic noise on stable states of a one-dimensional dynamical system that shows in its deterministic version a saddle-node bifurcation between monostable and bistable behaviour. The system is a modified…

Statistical Mechanics · Physics 2017-05-03 Johannes Falk , Marc Mendler , Barbara Drossel

The regulation of cellular function is often controlled at the level of gene transcription. Such genetic regulation usually consists of interacting networks, whereby gene products from a single network can act to control their own…

Biological Physics · Physics 2009-11-06 Jeff Hasty , Joel Pradines , Milos Dolnik , J. J. Collins

The effect of stochasticity, in the form of Gaussian white noise, in a predator-prey model with two distinct time-scales is presented. A supercritical singular Hopf bifurcation yields a Type II excitability in the deterministic model. We…

Dynamical Systems · Mathematics 2017-07-20 Susmita Sadhu

The development of neuromorphic systems based on memristive elements - resistors with memory - requires a fundamental understanding of their collective dynamics when organized in networks. Here, we study an experimentally inspired model of…

Statistical Mechanics · Physics 2017-01-18 Forrest C. Sheldon , Massimiliano Di Ventra

Many biological systems, such as metabolic pathways, exhibit bistability behavior: these biological systems exhibit two distinct stable states with switching between the two stable states controlled by certain conditions. Since…

Quantitative Methods · Quantitative Biology 2013-07-04 Yi Ming Zou

A stochastic model of autoregulated bursty gene expression by Kumar et al. [Phys. Rev. Lett. 113, 268105 (2014)] has been exactly solved in steady-state conditions under the implicit assumption that protein numbers are sufficiently large…

Subcellular Processes · Quantitative Biology 2020-03-18 Chen Jia , Ramon Grima

A naive model of many networked logistic maps with an excitation type coupling [Neural Networks, vol. 20, 102--108 (2007)], which is an extension of other low dimensional models, has been recently proposed to mimic the waking-sleeping…

Chaotic Dynamics · Physics 2009-06-13 Ricardo Lopez-Ruiz , Daniele Fournier-Prunaret

Intracellular biochemical networks fluctuate dynamically due to various internal and external sources of fluctuation. Dissecting the fluctuation into biologically relevant components is important for understanding how a cell controls and…

Molecular Networks · Quantitative Biology 2016-02-17 Tetsuya J. Kobayashi , Ryo Yokota , Kazuyuki Aihara

In BaFe2As2, structural and magnetic planar defects begin to proliferate below the structural phase transition, affecting descriptions of magnetism and superconductivity. We study using density-functional theory the stability and magnetic…

Superconductivity · Physics 2013-12-24 S. N. Khan , Aftab Alam , D. D. Johnson

Scattering of resonant radiation in a dense two-level medium is studied theoretically with account for local field effects and renormalization of the resonance frequency. Intrinsic optical bistability is viewed as switching between…

Quantum Physics · Physics 2015-05-20 M. G. Gladush , D. V. Kuznetsov , A. A. Panteleev , Vl. K. Roerich

We study theoretically a bistable systems with time-delayed feedback driven by weak periodic force. The effective potential function and the steady-state probability density are derived. The delay time and the strength of its feedback can…

Statistical Mechanics · Physics 2009-01-15 Rui-Hua Shao , Yong Chen

We consider a stochastic model of transcription factor (TF)-regulated gene expression. The model describes two genes: Gene A and Gene B which synthesize the TFs and the target gene proteins respectively. We show through analytic…

Quantitative Methods · Quantitative Biology 2009-11-13 Rajesh Karmakar , Indrani Bose

We study an excitable active rotator with slowly adapting nonlinear feedback and noise. Depending on the adaptation and the noise level, this system may display noise-induced spiking, noise-perturbed oscillations, or stochastic busting. We…

Adaptation and Self-Organizing Systems · Physics 2020-08-26 Igor Franović , Serhiy Yanchuk , Sebastian Eydam , Iva Bačić , Matthias Wolfrum

Feedback loops are major components of biochemical systems. Many systems show multiple such (positive or negative) feedback loops. Nevertheless, very few quantitative analyses address the question how such multiple feedback loops evolved.…

Quantitative Methods · Quantitative Biology 2010-03-08 M. Hafner , H. Koeppl , A. Wagner

We present a numerical and experimental study of feedback control of unstable cellular patterns in directional solidification (DS). The sample, a dilute binary alloy, solidifies in a 2D geometry under a control scheme which applies local…

Materials Science · Physics 2015-06-25 A. J. Pons , A. Karma , S. Akamatsu , M. Newey , A. Pomerance , H. Singer , W. Losert

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

Molecular Networks · Quantitative Biology 2015-04-28 Thierry Mora , Aleksandra M. Walczak

With phase space analysis approach, we investigate thoroughly the self-trapping phenomenon for two weakly coupled Bose-Einstein condensates (BEC) in a symmetric double-well potential. We identify two kinds of self-trapping by their…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 Guan-Fang Wang , Li-Bin Fu , Jie Liu

Birhythmicity occurs in many natural and artificial systems. In this paper we propose a self-feedback scheme to control birhythmicity. To establish the efficacy and generality of the proposed control scheme, we apply it on three birhythmic…

Adaptation and Self-Organizing Systems · Physics 2017-06-28 Debabrata Biswas , Tanmoy Banerjee , Juergen Kurths

The cell cycle is a tightly controlled process, yet its underlying genetic network shows marked differences across species. Which of the associated structural features follow solely from the ability to impose the appropriate gene expression…

Molecular Networks · Quantitative Biology 2015-06-12 M. Zagorski , A. Krzywicki , O. C. Martin