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We review uses of the generalized-ensemble algorithms for free-energy calculations in protein folding. Two of the well-known methods are multicanonical algorithm and replica-exchange method; the latter is also referred to as parallel…

Statistical Mechanics · Physics 2007-05-23 Y. Sugita , Y. Okamoto

This paper introduces a random-batch molecular dynamics (RBMD) package for fast simulations of particle systems at the nano/micro scale. Different from existing packages, the RBMD uses random batch methods for nonbonded interactions of…

Computational Physics · Physics 2025-11-11 Weihang Gao , Teng Zhao , Yongfa Guo , Jiuyang Liang , Huan Liu , Maoying Luo , Zedong Luo , Wei Qin , Yichao Wang , Qi Zhou , Shi Jin , Zhenli Xu

Molecular fragment or embedding methods are powerful techniques for overcoming scalability limitations in electronic structure theory by dividing large molecular systems into individual units that are small enough to be treated using…

Chemical Physics · Physics 2017-08-14 Jason N. Byrd , Robert W. Molt, , Rodney J. Bartlett , Beverly A. Sanders

Finding optimal solutions to combinatorial optimization problems is pivotal in both scientific and technological domains, within academic research and industrial applications. A considerable amount of effort has been invested in the…

Statistical Mechanics · Physics 2024-12-13 Zi-Song Shen , Feng Pan , Yao Wang , Yi-Ding Men , Wen-Biao Xu , Man-Hong Yung , Pan Zhang

Machine learning plays an important and growing role in molecular simulation. The newest version of the OpenMM molecular dynamics toolkit introduces new features to support the use of machine learning potentials. Arbitrary PyTorch models…

In this work the free energy of solid phases is computed for the Lennard-Jones potential and for a model of NaCl. The free energy is evaluated through the Einstein crystal/molecule methodologies using the Molecular Dynamics programs:…

Soft Condensed Matter · Physics 2012-10-16 J. L. Aragones , C. Valeriani , C. Vega

We present HTMPC, a Heavily Templated C++ library for large-scale simulations implementing multi-particle collision dynamics (MPC), a particle-based mesoscale hydrodynamic simulation method. The implementation is plugin-based, and designed…

Soft Condensed Matter · Physics 2024-06-24 Elmar Westphal , Segun Goh , Roland G. Winkler , Gerhard Gompper

Complex plasmas are low-temperature plasmas that contain micrometer-size particles in addition to the neutral gas particles and the ions and electrons that make up the plasma. The microparticles interact strongly and display a wealth of…

Plasma Physics · Physics 2014-12-09 Mierk Schwabe , David B. Graves

Accurate calculations of molecular crystals are crucial for drug design and crystal engineering. However, periodic high-level density functional calculations using hybrid functionals are often prohibitively expensive for relevant systems.…

Chemical Physics · Physics 2024-01-23 Johannes Hoja , Alexander List , A. Daniel Boese

In this paper, we develop a highly efficient molecular dynamics code fully implemented on graphics processing units for thermal conductivity calculations using the Green-Kubo formula. We compare two different schemes for force evaluation, a…

Materials Science · Physics 2013-03-14 Zheyong Fan , Topi Siro , Ari Harju

Multi-scale computer simulations combine the computationally efficient classical algorithms with more expensive but also more accurate ab-initio quantum mechanical algorithms. This work describes one implementation of multi-scale…

Computational Physics · Physics 2014-08-20 L. Leukkunen , T. Verho , O. Lopez-Acevedo

It is now established that nuclear quantum motion plays an important role in determining water's hydrogen bonding, structure, and dynamics. Such effects are important to include in density functional theory (DFT) based molecular dynamics…

Chemical Physics · Physics 2018-12-20 Daniel C. Elton , Michelle Fritz , M. -V. Fernández-Serra

The RMPCDMD software package performs hybrid Molecular Dynamics simulations, coupling Multiparticle Collision Dynamics to model the solvent and Molecular Dynamics to model suspended colloids, including hydrodynamics, thermal fluctuations,…

Computational Physics · Physics 2017-01-13 Pierre de Buyl , Mu-Jie Huang , Laurens Deprez

The interplay of electronic and nuclear degrees of freedom presents an outstanding problem in condensed matter physics and chemistry. Computational challenges arise especially for large systems, long time scales, in nonequilibrium, or in…

Strongly Correlated Electrons · Physics 2024-02-14 Arne Schobert , Jan Berges , Erik G. C. P. van Loon , Michael A. Sentef , Sergey Brener , Mariana Rossi , Tim O. Wehling

Pore forming toxins (PFTs) are virulent proteins released by several species, including many strains of bacteria, to attack and kill host cells. In this article, we focus on the utility of molecular dynamics (MD) simulations and the…

Soft Condensed Matter · Physics 2021-08-17 Rajat Desikan , Amit Behera , Prabal K. Maiti , K. Ganapathy Ayappa

Heliospheric plasmas require multi-scale and multi-physics considerations. On one hand, MHD codes are widely used for global simulations of the solar-terrestrial environments, but do not provide the most elaborate physical description of…

Computational Physics · Physics 2020-12-09 S. P. Moschou , I. V. Sokolov , O. Cohen , G. Toth , J. J. Drake , Z. Huang , C. Garraffo , J. D. Alvarado-Gómez , T. Gombosi

Many biological processes occur on time scales longer than those accessible to molecular dynamics simulations. Identifying collective variables (CVs) and introducing an external potential to accelerate them is a popular approach to address…

Computational Physics · Physics 2024-10-24 Enrico Trizio , Andrea Rizzi , Pablo M. Piaggi , Michele Invernizzi , Luigi Bonati

Graphics processing units have been extensively used to accelerate classical molecular dynamics simulations. However, there is much less progress on the acceleration of force evaluations for many-body potentials compared to pairwise ones.…

Computational Physics · Physics 2017-06-27 Zheyong Fan , Wei Chen , Ville Vierimaa , Ari Harju

Embedded systems become more and more widespread, especially autonomous ones, and clearly tend to be ubiquitous. In such systems, low-power and low-energy usage get ever more crucial. Furthermore, these issues also become paramount in…

Programming Languages · Computer Science 2007-05-23 Olivier Zendra

Ligand-receptor interactions are ubiquitous in biology and have become popular in materials in view of their applications to programmable self-assembly. Although, complex functionalities often emerge from the simultaneous interaction of…

Statistical Mechanics · Physics 2016-05-25 Lorenzo Di Michele , Stephan J. Bachmann , Lucia Parolini , Bortolo M. Mognetti
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