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Extracellular matrix (ECM) remodeling is central to a wide variety of healthy and diseased tissue processes. Unfortunately, predicting ECM remodeling under various chemical and mechanical conditions has proven to be excessively challenging,…

Molecular Networks · Quantitative Biology 2026-05-26 Hasi Hays , William J. Richardson

The study of biological systems witnessed a pervasive cross-fertilization between experimental investigation and computational methods. This gave rise to the development of new methodologies, able to tackle the complexity of biological…

Computational Engineering, Finance, and Science · Computer Science 2013-10-01 Daniela Besozzi , Giulio Caravagna , Paolo Cazzaniga , Marco Nobile , Dario Pescini , Alessandro Re

Evolutionary computing (EC) has proven to be effective in solving complex optimization and robotics problems. Unfortunately, typical Evolutionary Algorithms (EAs) are constrained by the computational capacity available to researchers. More…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-19 Rustam Eynaliyev , Houcen Liu

We present LBcuda, a GPU accelerated version of LBsoft, our open-source MPI-based software for the simulation of multi-component colloidal flows. We describe the design principles, the optimization and the resulting performance as compared…

Typical bio-signal processing front-ends are designed to maximize the quality of the recorded data, to allow faithful reproduction of the signal for monitoring and off-line processing. This leads to designs that have relatively large area…

Signal Processing · Electrical Eng. & Systems 2022-11-24 Mohammadali Sharifshazileh , Giacomo Indiveri

Synthetic molecular dynamics (synMD) trajectories from learned generative models have been proposed as a useful addition to the biomolecular simulation toolbox. The computational expense of explicitly integrating the equations of motion in…

Computational Physics · Physics 2022-05-05 John D. Russo , Daniel M. Zuckerman

Markerless 3D movement analysis from monocular video enables accessible biomechanical assessment in clinical and sports settings. However, most research-grade pipelines rely on GPU acceleration, limiting deployment on consumer-grade…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Yan Zhang , Xiong Zhao

Over the past decade there has been a growing interest in the development of parallel hardware systems for simulating large-scale networks of spiking neurons. Compared to other highly-parallel systems, GPU-accelerated solutions have the…

Neurons and Cognition · Quantitative Biology 2021-02-22 Bruno Golosio , Gianmarco Tiddia , Chiara De Luca , Elena Pastorelli , Francesco Simula , Pier Stanislao Paolucci

We present MARUT, a scalable multi-GPU computational fluid dynamics (CFD) framework designed for high-fidelity simulations of compressible flows spanning subsonic to hypersonic regimes, including chemically reacting nonequilibrium flows…

Computational Physics · Physics 2026-05-29 Trishit Mondal , Ameya D. Jagtap

Molecular simulations are an important tool for research in physics, chemistry, and biology. The capabilities of simulations can be greatly expanded by providing access to advanced sampling methods and techniques that permit calculation of…

An adpative integration technique for time advancement of particle motion in the context of coupled computational fluid dynamics (CFD) - discrete element method (DEM) simulations is presented in this work. CFD-DEM models provide an accurate…

Computational Physics · Physics 2018-02-28 Hariswaran Sitaraman , Ray Grout

A simple and efficient algorithm of the molecular-dynamics simulation of the hard disk system based on the Event-Driven method is developed. From the analysis of algorithm, the complexity is O(log N) per 1 event, and the constant…

Computational Physics · Physics 2009-10-31 Masaharu Isobe

The formation of the large-scale structure, the evolution and distribution of galaxies, quasars, and dark matter on cosmological scales, requires numerical simulations. Differentiable simulations provide gradients of the cosmological…

Instrumentation and Methods for Astrophysics · Physics 2022-11-21 Yin Li , Libin Lu , Chirag Modi , Drew Jamieson , Yucheng Zhang , Yu Feng , Wenda Zhou , Ngai Pok Kwan , François Lanusse , Leslie Greengard

Emerging multimodal LLMs (MLLMs) exhibit strong cross-modality perception and reasoning capabilities and hold great potential for various applications at edge. However, MLLMs typically consist of a compute-intensive modality encoder and a…

Hardware Architecture · Computer Science 2025-05-19 Kangbo Bai , Le Ye , Ru Huang , Tianyu Jia

AlphaFold predicts protein structures from the amino acid sequence at or near experimental resolution, solving the 50-year-old protein folding challenge, leading to progress by transforming large-scale genomics data into protein structures.…

Biomolecules · Quantitative Biology 2021-11-16 Bozitao Zhong , Xiaoming Su , Minhua Wen , Sichen Zuo , Liang Hong , James Lin

The field of plasma physics heavily relies on simulations to model various phenomena, such as instabilities, turbulence, and nonlinear behaviors that would otherwise be difficult to study from a purely theoretical approach. Simulations are…

Plasma Physics · Physics 2026-02-05 Giorgio Daneri

Neural network potentials (NNPs) enable large-scale molecular dynamics (MD) simulations of systems containing >10,000 atoms with the accuracy comparable to ab initio methods and play a crucial role in material studies. Although NNPs are…

Dimensionality reduction methods have found vast application as visualization tools in diverse areas of science. Although many different methods exist, their performance is often insufficient for providing quick insight into many…

Phase diagrams (PDs) illustrate the relative stability of competing phases under varying conditions, serving as critical tools for synthesizing complex materials. Reliable phase diagrams rely on precise free energy calculations, which are…

Materials Science · Physics 2026-02-09 Feng Zhang , Zhuo Ye , Maxim Moraru , Ying Wai Li , Weiyi Xia , Yongxin Yao , Cai-Zhuang Wang

Discovering the 3D atomic structure of molecules such as proteins and viruses is a fundamental research problem in biology and medicine. Electron Cryomicroscopy (Cryo-EM) is a promising vision-based technique for structure estimation which…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Marcus A. Brubaker , Ali Punjani , David J. Fleet