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Membrane-fluctuation-induced attraction between ligand--receptor sites binding neighboring membranes is studied using meshless membrane simulations and the Weil--Farago two-dimensional lattice model. For the adhesion sites binding two…

Soft Condensed Matter · Physics 2013-06-25 Hiroshi Noguchi

Non-classical two-step nucleation including preordering and crystal nucleation has been widely proposed to challenge the one-step nucleation framework in diverse materials, while what drives preordering has not been explicitly resolved yet.…

Soft Condensed Matter · Physics 2024-10-18 Renkuan Cao , Fan Peng , Yunhan Zhang , Hao Sun , Ziwei Liu , Tingyu Xu , Liangbin Li

The complex interplay between the various attractive and repulsive forces that mediate between biological membranes governs an astounding array of biological functions: cell adhesion, membrane fusion, self-assembly, binding-unbinding…

Soft Condensed Matter · Physics 2015-06-16 Y. Hanlumyuang , L. P. Liu , P. Sharma

Depletion forces play a role in the compaction and de-compation of chromosomal material in simple cells but it remains debatable whether they are sufficient to account for chromosomal collapse. We present coarse-grained molecular dynamics…

Soft Condensed Matter · Physics 2015-06-22 Tyler N. Shendruk , Martin Bertrand , Hendrick W. de Haan , James L. Harden , Gary W. Slater

Differentiation is a key cellular process in normal tissue development that is significantly altered in cancer. Although molecular signatures characterising pluripotency and multipotency exist, there is, as yet, no single quantitative mark…

Due to the potential applications in biomedical engineering, it becomes more and more important to understand the process of engulfment and internalization of nanoparticles (NPs) by cell membranes. Despite the fact that the interaction…

Biological Physics · Physics 2023-12-12 Ke Xiao , Jing Li , Rui Ma , Chen-Xu Wu

The dynamics of loops at the DNA denaturation transition is studied. A scaling argument is used to evaluate the asymptotic behavior of the autocorrelation function of the state of complementary bases (either open or closed). The long-time…

Statistical Mechanics · Physics 2008-07-03 Amir Bar , Yariv Kafri , David Mukamel

Information has an entropic character which can be analyzed within the Statistical Theory in molecular systems. R. Landauer and C.H. Bennett showed that a logical copy can be carried out in the limit of no dissipation if the computation is…

Biological Physics · Physics 2012-08-15 J. Ricardo Arias-Gonzalez

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

Soft Condensed Matter · Physics 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

Synthetic genetic circuits are implemented in living cells for their operation. During gene expression, proteins are produced from the respective genes, by formation of complexes through the process of transcription and translation. In…

Molecular Networks · Quantitative Biology 2021-12-10 Priya Chakraborty , Sayantari Ghosh

The entropic force exerted by the Brownian fluctuations of a grafted semiflexible polymer upon a rigid smooth wall are calculated both analytically and by Monte Carlo simulations. Such forces are thought to play an important role for…

Soft Condensed Matter · Physics 2007-05-23 Azam Gholami , Jan Wilhelm , Erwin Frey

We study Renyi and von Neumann entanglement entropies in the ground state of the one dimensional quarter-filled Hubbard model with periodic boundary conditions. We show that they exhibit an unexpected dependence on system size: for L=4 mod…

Strongly Correlated Electrons · Physics 2014-10-06 Pasquale Calabrese , Fabian H. L. Essler , Andreas M. Lauchli

Eukaryotic cells are often exposed to fluctuations in growth conditions as well as endogenous and exogenous stress-related agents. In addition, during development global patterns of gene transcription change dramatically, and these changes…

Genomics · Quantitative Biology 2008-12-23 John Herrick

Sintering refers to particle coalescence by heat, which has been known as a thermal phenomenon involving all aspects of natural science for centuries. It is particularly important in heterogeneous catalysis because normally sintering…

Shannon entropy is widely used to measure the complexity of DNA sequences but suffers from saturation effects that limit its discriminative power for long uniform segments. We introduce a novel metric, the entropy rank ratio R, which…

Information Theory · Computer Science 2025-11-10 Emmanuel Pio Pastore , Giuseppe Passarino , Peppino Sapia , Francesco De Rango

We demonstrate that linear combinations of subregion entropies with canceling boundary terms, commonly used to calculate the topological entanglement entropy, may suffer from spurious nontopological contributions even in models with zero…

Quantum Physics · Physics 2020-04-16 Dominic J. Williamson , Arpit Dua , Meng Cheng

Short-term synaptic plasticity (STSP) affects the efficiency of synaptic transmission for persistent presynaptic activities. We consider attractor neural networks, for which the attractors are given, in the absence of STSP, by cell…

Neurons and Cognition · Quantitative Biology 2019-04-09 Bulcsú Sándor , Claudius Gros

The effective interaction between a sphere with an open cavity (lock) and a spherical macroparticle (key), both immersed in a hard sphere fluid, is studied by means of Monte Carlo simulations. As a result, a 2d map of the key-lock effective…

Mesoscale and Nanoscale Physics · Physics 2015-05-20 Gerardo Odriozola , Felipe Jiménez-Ángeles , Marcelo Lozada-Cassou

Foundation models in genomics have shown mixed success compared to their counterparts in natural language processing. Yet, the reasons for their limited effectiveness remain poorly understood. In this work, we investigate the role of…

Machine Learning · Computer Science 2026-04-07 Maxime Rochkoulets , Lovro Vrček , Mile Šikić

The dynamics of polymer translocation through a pore has been the subject of recent theoretical and experimental works. We have considered theoretical estimates and performed computer simulations to understand the mechanism of DNA uptake…

Soft Condensed Matter · Physics 2009-11-07 Zeno Farkas , Imre Derenyi , Tamas Vicsek