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Non-equilibrium processes which convert chemical energy into mechanical motion enable the motility of organisms. Bundles of inextensible filaments driven by energy transduction of molecular motors form essential components of micron-scale…

Soft Condensed Matter · Physics 2013-06-13 Abhrajit Laskar , Rajeev Singh , Somdeb Ghose , Gayathri Jayaraman , P. B. Sunil Kumar , R. Adhikari

The present habilitation thesis in theoretical biological physics addresses two central dynamical processes in cells and organisms: (i) active motility and motility control and (ii) self-organized pattern formation. The unifying theme is…

Cell Behavior · Quantitative Biology 2018-03-21 Benjamin M. Friedrich

For steady-state and some other types of mechanical waves of an arbitrary form, intensity and nature, propagating in a free uniform waveguide, we present the following. Relations for the axial momentum as it directly follows from the…

General Physics · Physics 2016-05-17 Leonid I. Slepyan

Spiral waves are self-repeating waves that can form in excitable media, propagating outward from their center in a spiral pattern. Spiral waves have been observed in different natural phenomena and have been linked to medical conditions…

Cellular Automata and Lattice Gases · Physics 2020-08-11 Vincent Vangelista , Karl Amjad-Ali , Minhyeok Kwon , Paulo H. Acioli

We develop a framework for the general interpretation of the stochastic dynamical system near a limit cycle. Such quasi-periodic dynamics are commonly found in a variety of nonequilibrium systems, including the spontaneous oscillations of…

Statistical Mechanics · Physics 2018-10-30 Janaki Sheth , Dolores Bozovic , Alex Levine

Motile cilia are a striking example of functional cellular organelle, conserved across all the eukaryotic species. Motile cilia allow swimming of cells and small organisms and transport of liquids across epithelial tissues. Whilst the…

Tissues and Organs · Quantitative Biology 2020-01-13 Pietro Cicuta

Synchronization of activity among myocytes constituting vital organs, e.g., the heart, is crucial for physiological functions. Self-organized coordination in such heterogeneous ensemble of excitable and oscillatory cells is therefore of…

Tissues and Organs · Quantitative Biology 2024-08-21 Soling Zimik , Sitabhra Sinha

Single and collective cellular oscillations involving the actomyosin cytoskeleton have been observed in numerous biological systems. We show here that a generic model of a contractile material, which is turning over and contracts against an…

Biological Physics · Physics 2014-02-24 Kai Dierkes , Angughali Sumi , Jérôme Solon , Guillaume Salbreux

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

Biological Physics · Physics 2008-03-07 Debashish Chowdhury

The modeling of the beating of cilia and flagella in fluids is a particularly active field of study, given the biological relevance of these organelles. Various mathematical models have been proposed to represent the nonlinear dynamics of…

Soft Condensed Matter · Physics 2024-12-10 Irene Anello , François Alouges , Antonio De Simone

Self-oscillations underlie many natural phenomena such as heartbeat, ocean waves, and the pulsation of variable stars. From pendulum clocks to the behavior of animal groups, self-oscillation is one of the keys to the understanding of…

Sustained rhythmic oscillations, pulsing dynamics, emerge spontaneously when the local connection scheme is randomised in 3-value cellular automata that feature"glider" dynamics. Time-plots of pulsing measures maintain a distinct waveform…

Cellular Automata and Lattice Gases · Physics 2021-03-02 Andrew Wuensche , Edward Coxon

We investigate the possibility that narrowband oscillations may emerge from completely asynchronous, independent neural firing. We find that a population of asynchronous neurons may produce narrowband oscillations if each neuron fires…

Neurons and Cognition · Quantitative Biology 2015-12-08 Stephen V. Gliske , Eugene Lim , Katherine A. Holman , William C. Stacey , Christian G. Fink

Spatially distributed limited-cycle oscillators are seen in various physical and biological systems. In internal organs, mechanical motions are induced by the stimuli of spatially distributed limit-cycle oscillators. We study several…

Adaptation and Self-Organizing Systems · Physics 2017-04-05 Hidestugu Sakaguchi , Yuuki Mukae

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

Biological Physics · Physics 2022-07-13 T. N. Azevedo , L. G. Rizzi

Processive molecular motors which drive the traffic of organelles in cells move in a directed way along cytoskeletal filaments. On large time scales, they perform motor walks, i.e., peculiar random walks which arise from the repeated…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

It is known from the wave-like motion of microtubules in motility assays that the piconewton forces that motors produce can be sufficient to bend the filaments. In cellular phenomena such as cytosplasmic streaming, molecular motors…

Soft Condensed Matter · Physics 2017-07-11 Gabriele De Canio , Eric Lauga , Raymond E. Goldstein

This contribution reports on numerical simulations of 2D granular flows on erodible beds. The broad aim is to investigate whether simple flows of model granular matter exhibits spontaneous oscillatory motion in generic flow conditions, and…

Soft Condensed Matter · Physics 2012-11-27 Lydie Staron

Evidence from experimental studies shows that oscillations due to electro-mechanical coupling can be generated spontaneously in smooth muscle cells. Such cellular dynamics are known as \textit{pacemaker dynamics}. In this article we address…

Dynamical Systems · Mathematics 2022-01-19 Hammed O. Fatoyinbo , Richard G. Brown , David J. W. Simpson , Bruce van Brunt

Oscillatory biochemical signals and mechanical forces must coordinate robustly during development, yet the principles governing their mutual coupling remain poorly understood. In syncytial embryos and cell-free extracts, mitotic waves…

Biological Physics · Physics 2026-01-12 Lara Koehler , Elissavet Sandaltzopoulou , Frank Jülicher , Jan Brugués