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Drug discovery is a complex process that involves sequentially screening and examining a vast array of molecules to identify those with the target properties. This process, also referred to as sequential experimentation, faces challenges…

Artificial Intelligence · Computer Science 2024-05-08 Jinghai He , Cheng Hua , Yingfei Wang , Zeyu Zheng

The current work discusses how complex networks can be applied in order to aid economical development and stability at several scales and contexts. The following activities are involved: (a) compilation of several types of data related to…

Physics and Society · Physics 2007-05-23 Luciano da Fontoura Costa

Understanding infant development is one of the greatest scientific challenges of contemporary science. A large source of difficulty comes from the fact that the development of skills in infants results from the interactions of multiple…

Artificial Intelligence · Computer Science 2015-01-21 Pierre-Yves Oudeyer

A software program which aims to provide an exploration capability over the Search Space of potential drug molecules. The program explores the search space by generating random molecules, determining their fitness and then breeding a new…

Neural and Evolutionary Computing · Computer Science 2014-03-20 Mark Shackelford

Scientific research increasingly depends on robust and scalable IT infrastructures to support complex computational workflows. With the proliferation of services provided by research infrastructures, NRENs, and commercial cloud providers,…

Modern investigation in economics and in other sciences requires the ability to store, share, and replicate results and methods of experiments that are often multidisciplinary and yield a massive amount of data. Given the increasing…

Computational Finance · Quantitative Finance 2018-09-11 Jorge Faleiro , Edward Tsang

This paper aims at identifying emerging computational intelligence trends for the design and modeling of complex biometric-enabled infrastructure and systems. Biometric-enabled systems are evolving towards deep learning and deep inference…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Svetlana Yanushkevich , Shawn Eastwood , Kenneth Lai , Vlad Shmerko

This work describes the setup of an advanced technical infrastructure for collaborative software development (CDE) in large, distributed projects based on GitLab. We present its customization and extension, additional features and processes…

Software Engineering · Computer Science 2023-08-10 Felix Bach , Jochen Klar , Axel Loewe , Jorge Sánchez , Gunnar Seemann , Yung-Lin Huang , Robert Ulrich

Recent findings in neuroscience suggest that the human brain represents information in a geometric structure (for instance, through conceptual spaces). In order to communicate, we flatten the complex representation of entities and their…

Machine Learning · Computer Science 2020-02-05 Agnieszka Słowik , Abhinav Gupta , William L. Hamilton , Mateja Jamnik , Sean B. Holden

To handle the scarcity and heterogeneity of electroencephalography (EEG) data for Brain-Computer Interface (BCI) tasks, and to harness the power of large publicly available data sets, we propose Neuro-GPT, a foundation model consisting of…

Machine Learning · Computer Science 2024-03-05 Wenhui Cui , Woojae Jeong , Philipp Thölke , Takfarinas Medani , Karim Jerbi , Anand A. Joshi , Richard M. Leahy

The reproduction and replication of novel results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the issues closely revolve around the…

Software Engineering · Computer Science 2014-09-17 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

Motivation: Bioinformatics is faced with a variety of problems that require human involvement. Tasks like genome annotation, image analysis, knowledge-base construction and protein structure determination all benefit from human input. In…

Quantitative Methods · Quantitative Biology 2013-07-01 Benjamin M. Good , Andrew I. Su

The debate on data access and privacy is an ongoing one. It is kept alive by the never-ending changes/upgrades in (i) the shape of the data collected (in terms of size, diversity, sensitivity and quality), (ii) the laws governing data…

Computers and Society · Computer Science 2023-04-14 Fida K. Dankar

Urban growth sometimes leads to rigid infrastructure that struggles to adapt to changing demand. This paper introduces a novel approach, aiming to enable cities to evolve and respond more effectively to such dynamic demand. It identifies…

Computers and Society · Computer Science 2023-11-28 Xi Chen , Wei Hu , Jingru Yu , Ding Wang , Shengyue Yao , Yilun Lin , Fei-Yue Wang

Ethnomethodological fieldwork has long been acknowledged as a potentially valuable way of informing the design of technology. However, there is relatively little methodological support for this activity, particularly in relation to the…

Software Engineering · Computer Science 2024-11-15 Chris Hinds

Knowledge graphs, collectively as a knowledge network, have become critical tools for knowledge discovery in computable and explainable knowledge systems. Due to the semantic and structural complexities of biomedical data, these knowledge…

Other Quantitative Biology · Quantitative Biology 2025-09-29 Chunlei Wu , Hongfang Liu , Jason Flannick , Mark A. Musen , Andrew I. Su , Lawrence Hunter , Thomas M. Powers , Cathy H. Wu

As computer scientists working in bioinformatics/computational biology, we often face the challenge of coming up with an algorithm to answer a biological question. This occurs in many areas, such as variant calling, alignment, and assembly.…

Data Structures and Algorithms · Computer Science 2018-01-04 Paul Medvedev

The development of electronic health records (EHR) systems has enabled the collection of a vast amount of digitized patient data. However, utilizing EHR data for predictive modeling presents several challenges due to its unique…

Machine Learning · Computer Science 2024-08-14 Jiaqi Wang , Junyu Luo , Muchao Ye , Xiaochen Wang , Yuan Zhong , Aofei Chang , Guanjie Huang , Ziyi Yin , Cao Xiao , Jimeng Sun , Fenglong Ma

The Virtual Research Environment is an analysis platform developed at CERN serving the needs of scientific communities involved in European Projects. Its scope is to facilitate the development of end-to-end physics workflows, providing…

Machine learning is expected to fuel significant improvements in medical care. To ensure that fundamental principles such as beneficence, respect for human autonomy, prevention of harm, justice, privacy, and transparency are respected,…