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Autocatalysis is a deceptively simple concept, referring to the situation that a chemical species $X$ catalyzes its own formation. From the perspective of chemical kinetics, autocatalysts show a regime of super-linear growth. Given a…

Molecular Networks · Quantitative Biology 2021-07-08 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

Recent advances in generative AI have accelerated the discovery of novel chemicals and materials. However, scaling these discoveries to industrial production remains a major bottleneck due to the synthesis gap -- the need to develop…

Machine Learning · Computer Science 2025-08-19 Sakhinana Sagar Srinivas , Shivam Gupta , Venkataramana Runkana

Probabilistic Circuits (PCs) have emerged as an efficient framework for representing and learning complex probability distributions. Nevertheless, the existing body of research on PCs predominantly concentrates on data-driven parameter…

Machine Learning · Computer Science 2024-12-20 Athresh Karanam , Saurabh Mathur , Sahil Sidheekh , Sriraam Natarajan

This paper introduces a collaborative, human-centred taxonomy of AI, algorithmic and automation harms. We argue that existing taxonomies, while valuable, can be narrow, unclear, typically cater to practitioners and government, and often…

Developing robust representations of chemical structures that enable models to learn topological inductive biases is challenging. In this manuscript, we present a representation of atomistic systems. We begin by proving that our…

Machine Learning · Computer Science 2024-09-27 Rahul Khorana , Marcus Noack , Jin Qian

Information theory is concerned with the study of transmission, processing, extraction, and utilization of information. In its most abstract form, information is conceived as a means of resolving uncertainty. Shannon and Weaver (1949) were…

Computers and Society · Computer Science 2021-12-08 Birgitta Dresp-Langley

Most controlled natural languages (CNLs) are processed with the help of a pipeline architecture that relies on different software components. We investigate in this paper in an experimental way how well answer set programming (ASP) is…

Computation and Language · Computer Science 2014-08-12 Rolf Schwitter

Metabolic networks perform some of the most fundamental functions in living cells, including energy transduction and building block biosynthesis. While these are the best characterized networks in living systems, understanding their…

Molecular Networks · Quantitative Biology 2010-04-05 W. J. Riehl , P. L. Krapivsky , S. Redner , D. Segre

Artificial intelligence (AI) is transforming scientific research, with explainable AI methods like concept-based models (CMs) showing promise for new discoveries. However, in molecular science, CMs are less common than black-box models like…

Artificial Intelligence · Computer Science 2024-12-17 Zimin Zhang , Qianli Wu , Botao Xia , Fang Sun , Ziniu Hu , Yizhou Sun , Shichang Zhang

Intelligent information systems that contain emergent elements often encounter trust problems because results do not get sufficiently explained and the procedure itself can not be fully retraced. This is caused by a control flow depending…

Computers and Society · Computer Science 2021-04-30 Michael Guckert , Nils Gumpfer , Jennifer Hannig , Till Keller , Neil Urquhart

Several abstract machines that operate on symbolic input alphabets have been proposed in the last decade, for example, symbolic automata or lattice automata. Applications of these types of automata include software security analysis and…

Formal Languages and Automata Theory · Computer Science 2019-10-18 Andreas Stahlbauer

Shapes of cognition is a new conceptual paradigm for the computational cognitive modeling of Language-Endowed Intelligent Agents (LEIAs). Shapes are remembered constellations of sensory, linguistic, conceptual, episodic, and procedural…

Artificial Intelligence · Computer Science 2025-09-17 Marjorie McShane , Sergei Nirenburg , Sanjay Oruganti , Jesse English

The pursuit of artificial consciousness requires conceptual clarity to navigate its theoretical and empirical challenges. This paper introduces a composite, multilevel, and multidimensional model of consciousness as a heuristic framework to…

Artificial Intelligence · Computer Science 2025-01-03 K. Evers , M. Farisco , R. Chatila , B. D. Earp , I. T. Freire , F. Hamker , E. Nemeth , P. F. M. J. Verschure , M. Khamassi

Organic chemistry is undergoing a major paradigm shift, moving from a labor-intensive approach to a new era dominated by automation and artificial intelligence (AI). This transformative shift is being driven by technological advances, the…

Artificial Intelligence · Computer Science 2023-12-05 Chengchun Liu , Yuntian Chen , Fanyang Mo

This paper outlines a conceptual framework for understanding recent developments in information retrieval and natural language processing that attempts to integrate dense and sparse retrieval methods. I propose a representational approach…

Information Retrieval · Computer Science 2021-12-30 Jimmy Lin

Symbolic control is an abstraction-based controller synthesis approach that provides, algorithmically, certifiable-by-construction controllers for cyber-physical systems. Symbolic control approaches usually assume that full-state…

Systems and Control · Electrical Eng. & Systems 2022-11-01 Mahmoud Khaled , Kuize Zhang , Majid Zamani

Chemical reactions occur in energy, environmental, biological, and many other natural systems, and the inference of the reaction networks is essential to understand and design the chemical processes in engineering and life sciences. Yet,…

Molecular Networks · Quantitative Biology 2021-01-22 Weiqi Ji , Sili Deng

Consciousness is a sequential process of awareness which can focus on one piece of information at a time. This process of awareness experiences causation which underpins the notion of time while it interplays with matter and energy, forming…

Neurons and Cognition · Quantitative Biology 2023-01-24 Mahendra Samarawickrama

Atomic-level modeling performed at large scales enables the investigation of mesoscale materials properties with atom-by-atom resolution. The spatial complexity of such cross-scale simulations renders them unsuitable for simple human visual…

Materials Science · Physics 2022-04-05 Heejung Chung , Rodrigo Freitas , Gowoon Cheon , Evan J. Reed

In this paper, we consider two of the currently popular semantic frameworks: Abstract Meaning Representation (AMR)a more abstract framework, and Universal Conceptual Cognitive Annotation (UCCA)-an anchored framework. We use a corpus-based…

Artificial Intelligence · Computer Science 2022-07-26 Siyana Pavlova , Maxime Amblard , Bruno Guillaume
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