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Graph-based reaction systems were recently introduced as a generalization of the intensely studied set-based reaction systems. They deal with simple edge-labeled directed graphs, and dynamic semantics of graph-based reaction systems is…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-04 Hans-Jörg Kreowski , Aaron Lye

Artificial chemistry simulations produce many intriguing emergent behaviors, but they are often difficult to steer or control. This paper proposes a method for steering the dynamics of a classic artificial chemistry model, known as AlChemy…

Formal Languages and Automata Theory · Computer Science 2025-09-05 Devansh Vimal , Cole Mathis , Westley Weimer , Stephanie Forrest

Nature has found one method of organizing living matter, but maybe other options exist -- not yet discovered -- on how to create life. To study the life "as it could be" is the objective of an interdisciplinary field called Artificial Life…

Neural and Evolutionary Computing · Computer Science 2021-10-06 Carlos Gershenson , Jitka Cejkova

We provide a framework for experimentation at https://mbuliga.github.io/quinegraphs/ic-vs-chem.html#icvschem with two artificial chemistries: directed interaction combinators (dirIC, defined in section 2) and chemlambda. We are interested…

Artificial Intelligence · Computer Science 2020-05-14 M. Buliga

Chemical algorithms are statistical algorithms described and represented as chemical reaction networks. They are particularly attractive for traffic shaping and general control of network dynamics; they are analytically tractable, they…

Emerging Technologies · Computer Science 2016-01-21 Massimo Monti , Manolis Sifalakis , Christian F. Tschudin , Marco Luise

Conceptual Graphs (CGs) are a formalism to represent knowledge. However producing a CG database is complex. To the best of our knowledge, existing methods do not fully use the expressivity of CGs. It is particularly troublesome as it is…

Databases · Computer Science 2021-10-28 Adam Faci , Marie-Jeanne Lesot , Claire Laudy

Graph-Rewriting Automata (GRA) are an extension of Cellular Automata to a dynamic structure using local graph-rewriting rules. This work introduces linear algebra based tools that allow for a practical investigation of their behavior in…

Dynamical Systems · Mathematics 2025-11-11 Paul Cousin , Aude Maignan

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

Machine Learning · Computer Science 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

Recent research in molecular discovery has primarily been devoted to small, drug-like molecules, leaving many similarly important applications in material design without adequate technology. These applications often rely on more complex…

Robustness to a wide variety of negative factors and the ability to self-repair is an inherent and natural characteristic of all life forms on earth. As opposed to nature, man-made systems are in most cases not inherently robust and a…

Neural and Evolutionary Computing · Computer Science 2016-11-15 Christof Teuscher

Complex systems of intracellular biochemical reactions have a central role in regulating cell identities and functions. Biochemical reaction systems are typically studied using the language and tools of graph theory. However, graph…

Combinatorics · Mathematics 2021-09-24 Raffaella Mulas , Rubén J. Sánchez-García , Ben D. MacArthur

Chemical reaction mechanisms are the foundation of how chemists evaluate reactivity and feasibility, yet current Computer-Assisted Synthesis Planning (CASP) systems operate without this mechanistic reasoning. We introduce a computational…

Machine Learning · Computer Science 2026-04-20 Théo A. Neukomm , Zlatko Jončev , Philippe Schwaller

Artificial Neural Networks (ANN) are already heavily involved in methods and applications for frequent tasks in the field of computational chemistry such as representation of potential energy surfaces (PES) and spectroscopic predictions.…

Chemical Physics · Physics 2022-12-23 Silvan Käser , Luis Itza Vazquez-Salazar , Markus Meuwly , Kai Töpfer

We present a benchmark study of autonomous, chemical agents exhibiting associative learning of an environmental feature. Associative learning has been widely studied in cognitive science and artificial intelligence, but are most commonly…

Adaptation and Self-Organizing Systems · Physics 2022-10-12 Stuart Bartlett , David Louapre

Answering realistic questions about biological systems and pathways similar to the ones used by text books to test understanding of students about biological systems is one of our long term research goals. Often these questions require…

Artificial Intelligence · Computer Science 2013-06-25 Saadat Anwar , Chitta Baral , Katsumi Inoue

Structure and function in nanoscale atomistic assemblies are tightly coupled, and every atom with its specific position and even every electron will have a decisive effect on the electronic structure, and hence, on the molecular properties.…

Chemical Physics · Physics 2024-02-21 Katja-Sophia Csizi , Markus Reiher

We introduce here the concept of Artificial General Creatures (AGC) which encompasses "robotic or virtual agents with a wide enough range of capabilities to ensure their continued survival". With this in mind, we propose a research line…

Neural and Evolutionary Computing · Computer Science 2024-08-01 Kevin Godin-Dubois , Olivier Weissl , Karine Miras , Anna V. Kononova

The Bond Graph approach and the Chemical Reaction Network approach to modelling biomolecular systems developed independently. This paper brings together the two approaches by providing a bond graph interpretation of the chemical reaction…

Molecular Networks · Quantitative Biology 2019-07-04 Peter J. Gawthrop , Edmund J. Crampin

A method which casts the chemical source term computation into an artificial neural network (ANN)-inspired form is presented. This approach is well-suited for use on emerging supercomputing platforms that rely on graphical processing units…

Chemical Physics · Physics 2021-05-11 Shivam Barwey , Venkat Raman

Molecular graph generation is a fundamental problem for drug discovery and has been attracting growing attention. The problem is challenging since it requires not only generating chemically valid molecular structures but also optimizing…

Machine Learning · Computer Science 2020-02-28 Chence Shi , Minkai Xu , Zhaocheng Zhu , Weinan Zhang , Ming Zhang , Jian Tang