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The bacterium Escherichia coli (E. coli) moves in its natural environment in a series of straight runs, interrupted by tumbles which cause change of direction. It performs chemotaxis towards chemo-attractants by extending the duration of…

Quantitative Methods · Quantitative Biology 2010-07-12 Melissa Reneaux , Manoj Gopalakrishnan

The bacterium E. coli maneuvers itself to regions with high chemoattractant concentrations by performing two stereotypical moves: `runs', in which it moves in near straight lines, and `tumbles', in which it does not advance but changes…

Cell Behavior · Quantitative Biology 2007-11-29 Yariv Kafri , Rava Azeredo da Silveira

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. Previous models of run and tumble chemotaxis neglect one or more features of the…

Quantitative Methods · Quantitative Biology 2007-06-26 J. T. Locsei

Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find…

Fluid Dynamics · Physics 2015-11-04 A. E. Patteson , A. Gopinath , M. Goulian , P. E. Arratia

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. This paper presents calculations of the chemotactic drift velocity vd (the mean…

Quantitative Methods · Quantitative Biology 2008-04-16 J. T. Locsei , T. J. Pedley

Bacteria such as Escherichia coli (E. coli) exhibit biased motion if kept in a spatially non-uniform chemical environment. Here, we bring out unique time-dependent characteristics of bacterial chemotaxis, in response to a diffusing spatial…

Biological Physics · Physics 2018-12-05 Sibendu Samanta , Ritwik Layek , Shantimoy Kar , Sudipta Mukhopadhyay , Suman Chakraborty

Evolution has provided many organisms with sophisticated sensory systems that enable them to respond to signals in their environment. The response frequently involves alteration in the pattern of movement, such as the chemokinesis of the…

Molecular Networks · Quantitative Biology 2009-11-10 Reka Albert , Yu-wen Chiu , Hans G. Othmer

We provide a detailed stochastic description of the swimming motion of an E.coli bacterium in two dimension, where we resolve tumble events in time. For this purpose, we set up two Langevin equations for the orientation angle and speed…

Biological Physics · Physics 2018-11-14 Maximilian Seyrich , Zahra Alirezaeizanjani , Carsten Beta , Holger Stark

Motility is fundamental to the survival and proliferation of microorganisms. The E. coli bacterium propels itself using a bundle of rotating helical flagella. If one flagellum reverses its rotational direction, it leaves the bundle,…

Soft Condensed Matter · Physics 2025-04-30 Pierre Martin , Tapan Chandra Adhyapak , Holger Stark

Chemotaxis of the bacterium Escherichia coli is well understood in shallow chemical gradients, but its swimming behavior remains difficult to interpret in steep gradients. By focusing on single-cell trajectories from simulations, we…

Cell Behavior · Quantitative Biology 2018-02-14 Gabriele Micali , Remy Colin , Victor Sourjik , Robert G. Endres

One striking feature of bacterial motion is their ability to swim upstream along corners and crevices, by leveraging hydrodynamic interactions. This motion through anatomic ducts or medical devices might be at the origin of serious…

Soft Condensed Matter · Physics 2020-04-07 Nuris Figueroa-Morales , Aramis Rivera , Rodrigo Soto , Anke Lindner , Ernesto Altshuler , Eric Clement

Bacteria such as Escherichia coli move about in a series of runs and tumbles: while a run state (straight motion) entails all the flagellar motors spinning in counterclockwise mode, a tumble is caused by a shift in the state of one or more…

Quantitative Methods · Quantitative Biology 2020-01-08 C. S. Renadheer , Ushasi Roy , Manoj Gopalakrishnan

We study single cell E.coli chemotaxis in a spatio-temporally varying attractant environment. Modeling the attractant concentration in the form of a traveling sine wave, we measure in our simulations, the chemotactic drift velocity of the…

Cell Behavior · Quantitative Biology 2025-06-06 Shobhan Dev Mandal , Sakuntala Chatterjee

Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. This process is characterised by a drift velocity that depends non-linearly on the concentration of chemical species and its…

Fluid Dynamics · Physics 2026-05-07 Adam Gargasson , Julien Bouvard , Carine Douarche , Peter Mergaert , Harold Auradou

Near a solid boundary, E. coli swims in clockwise circular motion. We provide a hydrodynamic model for this behavior. We show that circular trajectories are natural consequences of force-free and torque-free swimming, and the hydrodynamic…

Soft Condensed Matter · Physics 2016-08-31 Eric Lauga , Willow R. DiLuzio , George M. Whitesides , Howard A. Stone

One of simplest examples of navigation found in nature is run-and-tumble chemotaxis. Tumbles reorient cells randomly, and cells can drift toward attractants or away from repellents by biasing the frequency of these events. The post-tumble…

Soft Condensed Matter · Physics 2017-09-14 Julius B. Kirkegaard , Raymond E. Goldstein

Motile bacteria are known to accumulate at surfaces, eventually leading to changes in bacterial motility and bio-film formation. We use a novel two-colour, three-dimensional Lagrangian tracking technique, to follow simultaneously the body…

{\it E. coli} bacteria swim in straight runs interrupted by sudden reorientation events called tumbles. The resulting random walks give rise to density fluctuations that can be derived analytically in the limit of non interacting particles…

Statistical Mechanics · Physics 2013-09-05 M. Paoluzzi , R. Di Leonardo , L. Angelani

Mathematical models have been widely used to describe the collective movement of bacteria by chemotaxis. In particular, bacterial concentration waves traveling in a narrow channel have been experimentally observed and can be precisely…

Analysis of PDEs · Mathematics 2016-04-15 Casimir Emako , Charlène Gayrard , Axel Buguin , Luís Neves de Almeida , Nicolas Vauchelet

In many situations bacteria move in complex environments, as for example in soils, oceans or the human gut-track microbiome. In these natural environments, carrier fluids such as mucus or reproductive fluids show complex structure…

Soft Condensed Matter · Physics 2022-06-22 Martyna Goral , Eric Clement , Thierry Darnige , Teresa Lopez-Leon , Anke Lindner
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