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Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…

Quantitative Methods · Quantitative Biology 2020-03-03 Yan Ge , Philipp Rosendahl , Claudio Durán , Nicole Töpfner , Sara Ciucci , Jochen Guck , Carlo Vittorio Cannistraci

Melanoma is the most dangerous form of skin cancer, which is responsible for the majority of skin cancer-related deaths. Early diagnosis of melanoma can significantly reduce mortality rates and treatment costs. Therefore, skin cancer…

Hardware Architecture · Computer Science 2021-12-13 Shereen Afifi , Hamid GholamHosseini , Roopak Sinha

Cell image classification methods are currently being used in numerous applications in cell biology and medicine. Applications include understanding the effects of genes and drugs in screening experiments, understanding the role and…

Quantitative Methods · Quantitative Biology 2022-03-04 Mohammad Shifat-E-Rabbi , Xuwang Yin , Cailey Elizabeth Fitzgerald , Gustavo K. Rohde

Digital copiers and printers are widely used nowadays. One of the most important things people care about is copying or printing quality. In order to improve it, we previously came up with an SVM-based classification method to classify…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Shaoyuan Xu , Cheng Lu , Mark Shaw , Peter Bauer , Jan P. Allebach

The detection and segmentation of white blood cells in blood smear images is a key step in medical diagnostics, supporting various downstream tasks such as automated blood cell counting, morphological analysis, cell classification, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Michael Deutges , Chen Yang , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

We introduce a machine learning-based method for fully automated diagnosis of sickle cell disease of poor-quality unstained images of a mobile microscope. Our method is capable of distinguishing between diseased, trait (carrier), and normal…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Sahar A. Nasser , Debjani Paul , Suyash P. Awate

Previous works on segmentation of SEM (scanning electron microscope) blood cell image ignore the semantic segmentation approach of whole-slide blood cell segmentation. In the proposed work, we address the problem of whole-slide blood cell…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Muhammad Shahzad , Arif Iqbal Umar , Muazzam A. Khan , Syed Hamad Shirazi , Zakir Khan , Waqas Yousaf

Wireless Capsule Endoscopy (WCE) is relatively a new technology to examine the entire GI trace. During an examination, it captures more than 55,000 frames. Reviewing all these images is time-consuming and prone to human error. It has been a…

Computer Vision and Pattern Recognition · Computer Science 2017-11-20 Omid Haji Maghsoudi

Support vector machine (SVM) is one of the most popular classification algorithms in the machine learning literature. We demonstrate that SVM can be used to balance covariates and estimate average causal effects under the unconfoundedness…

Methodology · Statistics 2021-07-02 Alexander Tarr , Kosuke Imai

The pixel's classification of images obtained from random heterogeneous materials is a relevant step to compute their physical properties, like Effective Transport Coefficients (ETC), during a characterization process as stochastic…

Support vector machines represent a promising development in machine learning research that is not widely used within the remote sensing community. This paper reports the results of Multispectral(Landsat-7 ETM+) and Hyperspectral DAIS)data…

Neural and Evolutionary Computing · Computer Science 2009-11-13 Mahesh Pal , Paul M. Mather

Computational microscopy, in which hardware and algorithms of an imaging system are jointly designed, shows promise for making imaging systems that cost less, perform more robustly, and collect new types of information. Often, the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Henry Pinkard , Cherry Liu , Fanice Nyatigo , Daniel A. Fletcher , Laura Waller

Support vector machines (SVMs) appeared in the early nineties as optimal margin classifiers in the context of Vapnik's statistical learning theory. Since then SVMs have been successfully applied to real-world data analysis problems, often…

Statistics Theory · Mathematics 2016-08-16 Javier M. Moguerza , Alberto Muñoz

Melanoma classification is a serious stage to identify the skin disease. It is considered a challenging process due to the intra-class discrepancy of melanomas, skin lesions low contrast, and the artifacts in the dermoscopy images,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Yanhui Guo , Amira S. Ashour

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Cell instance segmentation is a fundamental task in digital pathology with broad clinical applications. Recently, vision foundation models, which are predominantly based on Vision Transformers (ViTs), have achieved remarkable success in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yang Yang , Xijie Xu , Yixun Zhou , Jie Zheng

Cellular and molecular imaging techniques and models have been developed to characterize single stages of viral proliferation after focal infection of cells in vitro. The fast and automatic classification of cell imaging data may prove…

Computer Vision and Pattern Recognition · Computer Science 2020-11-11 Birgitta Dresp-Langley , John M. Wandeto

Recent advances in healthcare technologies have led to the availability of large amounts of biological samples across several techniques and applications. In particular, in the last few years, Raman spectroscopy analysis of biological…

Quantitative Methods · Quantitative Biology 2025-06-24 Marco Piazza , Andrea Spinelli , Francesca Maggioni , Marzia Bedoni , Enza Messina

The aim of this work is to propose an ensemble of descriptors for Melanoma Classification, whose performance has been evaluated on validation and test datasets of the melanoma challenge 2018. The system proposed here achieves a strong…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Loris Nanni , Alessandra Lumini , Stefano Ghidoni