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In vision-language pre-training (VLP), masked image modeling (MIM) has recently been introduced for fine-grained cross-modal alignment. However, in most existing methods, the reconstruction targets for MIM lack high-level semantics, and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-04 Haowei Liu , Yaya Shi , Haiyang Xu , Chunfeng Yuan , Qinghao Ye , Chenliang Li , Ming Yan , Ji Zhang , Fei Huang , Bing Li , Weiming Hu

Biological multimodal large language models (MLLMs) have emerged as powerful foundation models for scientific discovery. However, existing models are specialized to a single modality, limiting their ability to solve inherently cross-modal…

Machine Learning · Computer Science 2026-03-17 Wonbin Lee , Dongki Kim , Sung Ju Hwang

Medical vision-language pretraining models (VLPM) have achieved remarkable progress in fusing chest X-rays (CXR) with clinical texts, introducing image-text data binding approaches that enable zero-shot learning and downstream clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yuan Gao , Sangwook Kim , David E Austin , Chris McIntosh

Composed image retrieval (CIR) requires multi-modal models to jointly reason over visual content and semantic modifications presented in text-image input pairs. While current CIR models achieve strong performance on common benchmark cases,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Chenchen Zhao , Jianhuan Zhuo , Muxi Chen , Zhaohua Zhang , Wenyu Jiang , Tianwen Jiang , Qiuyong Xiao , Jihong Zhang , Qiang Xu

Motivation: Biomedical knowledge graphs (KGs) are crucial for drug discovery and disease understanding, yet their completion and reasoning are challenging. Knowledge Embedding (KE) methods capture global semantics but struggle with dynamic…

Artificial Intelligence · Computer Science 2025-07-23 Yitong Lin , Jiaying He , Jiahe Chen , Xinnan Zhu , Jianwei Zheng , Tao Bo

Deep learning has revolutionized biomedical research by providing sophisticated methods to handle complex, high-dimensional data. Multimodal deep learning (MDL) further enhances this capability by integrating diverse data types such as…

Machine Learning · Computer Science 2026-03-13 Valerio Guarrasi , Fatih Aksu , Camillo Maria Caruso , Francesco Di Feola , Aurora Rofena , Filippo Ruffini , Paolo Soda

The increasing use of medical imaging in healthcare settings presents a significant challenge due to the increasing workload for radiologists, yet it also offers opportunity for enhancing healthcare outcomes if effectively leveraged. 3D…

Current Computer-Aided Diagnosis (CAD) methods mainly depend on medical images. The clinical information, which usually needs to be considered in practical clinical diagnosis, has not been fully employed in CAD. In this paper, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Songxiao Yang , Xiabi Liu , Zhongshu Zheng , Wei Wang , Xiaohong Ma

Real world multimedia data is often composed of multiple modalities such as an image or a video with associated text (e.g. captions, user comments, etc.) and metadata. Such multimodal data packages are prone to manipulations, where a subset…

Multimedia · Computer Science 2018-07-02 Ayush Jaiswal , Ekraam Sabir , Wael AbdAlmageed , Premkumar Natarajan

The explosive increase and ubiquitous accessibility of visual data on the Web have led to the prosperity of research activity in image search or retrieval. With the ignorance of visual content as a ranking clue, methods with text search…

Multimedia · Computer Science 2017-09-05 Wengang Zhou , Houqiang Li , Qi Tian

In medical imaging, the characteristics purely derived from a disease should reflect the extent to which abnormal findings deviate from the normal features. Indeed, physicians often need corresponding images without abnormal findings of…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Kazuma Kobayashi , Ryuichiro Hataya , Yusuke Kurose , Mototaka Miyake , Masamichi Takahashi , Akiko Nakagawa , Tatsuya Harada , Ryuji Hamamoto

Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified…

Computation and Language · Computer Science 2024-07-16 Kriti Bhattarai , Inez Y. Oh , Zachary B. Abrams , Albert M. Lai

Text-to-image retrieval aims to find the relevant images based on a text query, which is important in various use-cases, such as digital libraries, e-commerce, and multimedia databases. Although Multimodal Large Language Models (MLLMs)…

Information Retrieval · Computer Science 2024-04-04 Zijun Long , Xuri Ge , Richard Mccreadie , Joemon Jose

Despite the success of conventional collaborative filtering (CF) approaches for recommendation systems, they exhibit limitations in leveraging semantic knowledge within the textual attributes of users and items. Recent focus on the…

Information Retrieval · Computer Science 2024-08-19 Zhongzhou Liu , Hao Zhang , Kuicai Dong , Yuan Fang

Sequential Recommender Systems (SRS) aim to predict users' next interaction based on their historical behaviors, while still facing the challenge of data sparsity. With the rapid advancement of Multimodal Large Language Models (MLLMs),…

Information Retrieval · Computer Science 2026-02-17 Mingyao Huang , Qidong Liu , Wenxuan Yang , Moranxin Wang , Yuqi Sun , Haiping Zhu , Feng Tian , Yan Chen

One of the challenges in Content-Based Image Retrieval (CBIR) is to reduce the semantic gaps between low-level features and high-level semantic concepts. In CBIR, the images are represented in the feature space and the performance of CBIR…

Computer Vision and Pattern Recognition · Computer Science 2017-03-27 Nouman Ali , Danish Ali Mazhar , Zeshan Iqbal , Rehan Ashraf , Jawad Ahmed , Farrukh Zeeshan Khan

Multi-modal data abounds in biomedicine, such as radiology images and reports. Interpreting this data at scale is essential for improving clinical care and accelerating clinical research. Biomedical text with its complex semantics poses…

The image-text retrieval task aims to retrieve relevant information from a given image or text. The main challenge is to unify multimodal representation and distinguish fine-grained differences across modalities, thereby finding similar…

Multimedia · Computer Science 2024-05-20 Ziyu Gong , Chengcheng Mai , Yihua Huang

This survey provides a comprehensive overview of recent advances in multimodal alignment and fusion within the field of machine learning, driven by the increasing availability and diversity of data modalities such as text, images, audio,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Songtao Li , Hao Tang

Omics fusion has emerged as a crucial preprocessing approach in the field of medical image processing, providing significant assistance to several studies. One of the challenges encountered in the integration of omics data is the presence…

Quantitative Methods · Quantitative Biology 2025-02-17 Jiabao Sheng , SaiKit Lam , Jiang Zhang , Yuanpeng Zhang , Jing Cai
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