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The purpose of this work is to propose a non-Markovian and nonlinear model of subdiffusive transport that involves adhesion affects the cells escape rates form position x, with chemotaxis. This leads the escape rates to be dependent on the…

Cell Behavior · Quantitative Biology 2016-03-02 Akram Al-Sabbagh

Cell migration often exhibits long-range temporal correlations and anomalous diffusion, even in the absence of external guidance cues such as chemical gradients or topographical constraints. These observations raise a fundamental question:…

Quantitative Methods · Quantitative Biology 2025-11-25 Gustavo Cornejo-Olea , Lucas Buvinic , Jerome Darbon , Radek Erban , Andrea Ravasio , Anastasios Matzavinos

Many diffusion processes in nature and society were found to be anomalous, in the sense of being fundamentally different from conventional Brownian motion. An important example is the migration of biological cells, which exhibits…

Statistical Mechanics · Physics 2018-02-13 J. M. Nava-Sedeno , H. Hatzikirou , R. Klages , A. Deutsch

The motion of an artificial micro-scale swimmer that uses a chemical reaction catalyzed on its own surface to achieve autonomous propulsion is fully characterized experimentally. It is shown that at short times, it has a substantial…

We propose a continuum model for pattern formation, based on the multiphase model framework, to explore in vitro cell patterning within an extracellular matrix. We demonstrate that, within this framework, chemotaxis-driven cell migration…

Cell Behavior · Quantitative Biology 2022-11-21 Georgina Al-Badri , James B. Phillips , Rebecca J. Shipley , Nicholas C. Ovenden

We consider an evolutionary PDE system coupling the Cahn-Hilliard equation with singular potential, mass source and transport effects, to a Brinkman-type relation for the macroscopic velocity field and to a further equation describing the…

Analysis of PDEs · Mathematics 2024-11-20 Giulio Schimperna

Chemotaxis is the physical phenomenon that bacteria adjust their motions according to chemical stimulus. A classical model for this phenomenon is a kinetic equation that describes the velocity jump process whose tumbling/transition kernel…

Analysis of PDEs · Mathematics 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

Chemotaxis is a fundamental guidance mechanism of cells and organisms, responsible for attracting microbes to food, embryonic cells into developing tissues, immune cells to infection sites, animals towards potential mates, and…

Quantitative Methods · Quantitative Biology 2018-06-26 K. J. Painter

Active fluids made of powered suspended particles have unique abilities to self-generate flow and density structures. How such dynamics can be triggered and leveraged by external cues is a key question of both biological and applied…

Soft Condensed Matter · Physics 2025-07-21 Malo Marmol , Cécile Cottin-Bizonne , Andrejs Cebers , Damien Faivre , Christophe Ybert

Collectives of actively-moving particles can spontaneously separate into dilute and dense phases -- a fascinating phenomenon known as motility-induced phase separation (MIPS). MIPS is well-studied for randomly-moving particles with no…

Biological Physics · Physics 2023-01-31 Hongbo Zhao , Andrej Košmrlj , Sujit S. Datta

Enzymes have been recently proposed to have mechanical activity associated with their chemical activity. In a number of recent studies, it has been reported that enzymes undergo enhanced diffusion in the presence of their corresponding…

Biological Physics · Physics 2021-04-07 Jaime Agudo-Canalejo , Tunrayo Adeleke-Larodo , Pierre Illien , Ramin Golestanian

Self-chemophoresis is an appealing and quite successful interpretation of the motility exhibited by certain chemically active colloidal particles suspended in a solution of their "fuel": the particle has a phoretic response to…

Soft Condensed Matter · Physics 2026-01-06 Alvaro Domínguez , Mihail N. Popescu

We enter the details of two recent articles concerning as many chemotaxis models, one nonlinear and the other linear, and both with produced chemoattractant and saturated chemorepellent. These works, when properly analyzed, leave open room…

Analysis of PDEs · Mathematics 2022-11-23 Silvia Frassu , Tongxing Li , Giuseppe Viglialoro

Experiments show that the movement of eukaryotic cells is regulated by a process of phase separation of two competing enzymes on the cell membrane, that effectively amplifies shallow external gradients of chemical attractant. Notably, the…

Statistical Mechanics · Physics 2008-12-19 Teresa Ferraro , Antonio de Candia , Andrea Gamba , Antonio Coniglio

We consider a phenotype-switching chemotaxis model for aggregation, in which a chemotactic population is capable of switching back and forth between a chemotaxing state (performing chemotactic movement) and a secreting state (producing the…

Analysis of PDEs · Mathematics 2022-10-11 Kevin J Painter , Michael Winkler

Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. This process is characterised by a drift velocity that depends non-linearly on the concentration of chemical species and its…

Fluid Dynamics · Physics 2026-05-07 Adam Gargasson , Julien Bouvard , Carine Douarche , Peter Mergaert , Harold Auradou

A novel trait-structured Keller-Segel model that explores the dynamics of a migrating cell population guided by chemotaxis in response to an external ligand concentration is derived and analysed. Unlike traditional Keller-Segel models, this…

Cell Behavior · Quantitative Biology 2025-02-27 Viktoria Freingruber , Tommaso Lorenzi , Kevin J. Painter , Mariya Ptashnyk

This paper deals with the micro-macro derivation of virus models coupled with a reaction diffusion models that generates the dynamics in space of the virus particles. The first part of the presentation focuses, starting from [5, 6] on a…

Dynamical Systems · Mathematics 2021-12-15 Diletta Burini , Nadia Chouhad

Cells are constantly exposed to diverse stimuli-chemical, mechanical, or electrical-that guide their movement. In physiological conditions, these signals often overlap, as seen during infections, where neutrophils and dendritic cells…

Biological Physics · Physics 2026-03-25 Emiliano Perez Ipiña , Brian A. Camley

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

Biological Physics · Physics 2022-11-22 Tiankai Zhao , Hongyan Yuan