Related papers: Noise-assisted spike propagation in myelinated neu…
First return maps of interspike intervals for biological neurons that generate repetitive bursts of impulses can display stereotyped structures (neuronal signatures). Such structures have been linked to the possibility of multicoding and…
The activity generated by an ensemble of neurons is affected by various noise sources. It is a well-recognised challenge to understand the effects of noise on the stability of such networks. We demonstrate that the patterns of activity…
The Hodgkin-Huxley model of nerve pulse propagation relies on ion currents through specific resistors called ion channels. We discuss a number of classical thermodynamic findings on nerves that are not contained in this classical theory.…
We study the response of the Hodgkin-Huxley neuron stimulated periodically by biphasic rectangular current pulses. The optimal response for charge-balanced input is obtained for cathodic-first pulses with an inter-phase gap (IPG)…
The binding neuron model is inspired by numerical simulation of Hodgkin-Huxley-type point neuron, as well as by the leaky integrate-and-fire model. In the binding neuron, the trace of an input is remembered for a fixed period of time after…
A spiking neuron ``computes'' by transforming a complex dynamical input into a train of action potentials, or spikes. The computation performed by the neuron can be formulated as dimensional reduction, or feature detection, followed by a…
The first-passage-time distribution of a leaky integrate-and-fire neuron driven by a characteristically coloured noise is approximated by matching a transient and a steady-state solution of the membrane voltage distribution. These…
Noise in spiking neurons is commonly modeled by a noisy input current or by generating output spikes stochastically with a voltage-dependent hazard rate ("escape noise"). While input noise lends itself to modeling biophysical noise…
We report the phenomenon of frequency clustering in a network of Hodgkin-Huxley neurons with spike timing-dependent plasticity. The clustering leads to a splitting of a neural population into a few groups synchronized at different…
Voltage-dependent ion channels determine the electric properties of axonal cell membranes. They not only allow the passage of ions through the cell membrane but also contribute to an additional charging of the cell membrane resulting in the…
We describe general characteristics of the Hodgkin-Huxley neuron's response to a periodic train of short current pulses with Gaussian noise. The deterministic neuron is bistable for antiresonant frequencies. When the stimuli arrive at the…
Realistic networks display heterogeneous transmission delays. We analyze here the limits of large stochastic multi-populations networks with stochastic coupling and random interconnection delays. We show that depending on the nature of the…
The Hodgkin-Huxley model describes the conduction of the nervous impulse through the axon, whose membrane's electric response can be described employing multiple connected electric circuits containing capacitors, voltage sources, and…
This article is devoted to the theoretical and numerical analysis of a network of excitatory and inhibitory neurons of Hodgkin-Huxley (HH) type, for which the topology is inspired by that of a single local layer of visual cortex V1. Our…
We consider the problem of optimizing signal transmission through multi-channel noisy devices. We investigate an array of bithreshold noisy devices which are connected in parallel and convergent on a summing center. Utilizing the concept of…
Single neuron models have a long tradition in computational neuroscience. Detailed biophysical models such as the Hodgkin-Huxley model as well as simplified neuron models such as the class of integrate-and-fire models relate the input…
This article develops a fundamental insight into the behavior of neuronal membranes, focusing on their responses to stimuli measured with power spectra in the frequency domain. It explores the use of linear and nonlinear (quadratic…
A dynamical mean-field approximation (DMA) previously proposed by the present author [H. Hasegawa, Phys. Rev E {\bf 67}, 041903 (2003)] has been extended to ensembles described by a general noisy spiking neuron model. Ensembles of $N$-unit…
In the last fifteen years a debate emerged about the validity of the famous Hodgkin-Huxley model for nerve impulse. Mechanical models have been proposed. This note reviews the experimental properties of the nerve impulse and discusses the…
We show that the action potential signals generated inside axons are reaction-diffusion solitons or reaction-diffusion waves, refuting the Hodgkin and Huxley hypothesis that action potentials propagate along axons with an elastic wave…