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Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

Machine Learning · Statistics 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

We calculate a measure of statistical complexity from the global dynamics of electroencephalographic (EEG) signals from healthy subjects and epileptic patients, and are able to stablish a criterion to characterize the collective behavior in…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 M. Escalona-Moran , M. G. Cosenza , R. Lopez-Ruiz , P. Garcia

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that…

Neurons and Cognition · Quantitative Biology 2016-10-07 Christian Geier , Alexander Rothkegel , Christian E. Elger , Klaus Lehnertz

The human brain is liable to undergo substantial alterations, anatomically and functionally with aging. Cognitive brain aging can either be healthy or degenerative in nature. Such degeneration of cognitive ability can lead to disorders such…

Signal Processing · Electrical Eng. & Systems 2022-06-17 Prerna Singh , Tapan Kumar Gandhi , Lalan Kumar

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

Optimization and Control · Mathematics 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

We investigate states of enhanced activity in a biological neuronal network composed of pulse-coupled oscillators. The synaptic couplings between the neurons are dynamic, modeling spike time dependent plasticity. The network exhibits…

Disordered Systems and Neural Networks · Physics 2012-08-17 Daniel Ritterskamp , Rudolf Friedrich

The study's objective is to explore the distinctions in the functional brain network connectivity between Alzheimer's Disease (AD) patients and normal controls using Functional Magnetic Resonance Imaging (fMRI). The study included 590…

Neurons and Cognition · Quantitative Biology 2023-05-17 Yongcheng Yao

Over one third of the estimated 3 million people with epilepsy in the US are medication resistant. Responsive neurostimulation from chronically implanted electrodes provides a promising treatment option and alternative to resective surgery.…

Neural systems can be modeled as networks of functionally connected neural elements. The resulting network can be analyzed using mathematical tools from network science and graph theory to quantify the system's topological organization and…

Neurons and Cognition · Quantitative Biology 2020-07-01 Richard F. Betzel , Katherine C. Wood , Christopher Angeloni , Maria Neimark Geffen , Danielle S. Bassett

The human brain is organized into large-scale functional modules that have been shown to evolve in childhood and adolescence. However, it remains unknown whether structural brain networks are similarly refined during development,…

The brain is a paradigmatic example of a complex system as its functionality emerges as a global property of local mesoscopic and microscopic interactions. Complex network theory allows to elicit the functional architecture of the brain in…

Neurons and Cognition · Quantitative Biology 2017-01-18 Rossana Mastrandrea , Andrea Gabrielli , Fabrizio Piras , Gianfranco Spalletta , Guido Caldarelli , Tommaso Gili

While differences in patterns of functional connectivity and neural synchronization have been reported between individuals on the autism spectrum and neurotypical peers at various age stages, these differences appear to be subtle and may…

Neurons and Cognition · Quantitative Biology 2025-07-15 Sungwoo Ahn , Leonid L Rubchinsky , Evie A Malaia

Graph-theoretical analyses of complex brain networks is a rapidly evolving field with a strong impact for neuroscientific and related clinical research. Due to a number of confounding variables, however, a reliable and meaningful…

Neurons and Cognition · Quantitative Biology 2014-08-27 Gerrit Ansmann , Klaus Lehnertz

The functional network of the brain continually adapts to changing environmental demands. The environmental changes closely connect with changes of active cognitive processes. In recent years, the network approach has emerged as a promising…

Neurons and Cognition · Quantitative Biology 2024-03-13 Ilya Ernston , Arsenii Onuchin , Timofey Adamovich

Purpose: The understanding of brain activity, and in particular events such as epileptic seizures, lies on the characterisation of the dynamics of the neural networks. The theory of non-linear dynamics provides signal analysis techniques…

Medical Physics · Physics 2007-05-23 C. Silva , I. R. Pimentel , A. Andrade , J. P. Foreid , E. Ducla-Soares

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

Experimental fMRI studies have shown that spontaneous brain activity i.e. in the absence of any external input, exhibit complex spatial and temporal patterns of co-activity between segregated brain regions. These so-called large-scale…

Adaptation and Self-Organizing Systems · Physics 2015-06-23 Vesna Vuksanović , Philipp Hövel

In a recent paper, Bassett et al. (2011) have analyzed the static and dynamic organization of functional brain networks in humans. We here focus on the first claim made in this paper, which states that the static modular structure of such…

Quantitative Methods · Quantitative Biology 2011-06-30 Cedric E. Ginestet , Jonny O'Muircheartaigh , Owen G. O'Daly , Andrew Simmons
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