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We study a novel phase of active polar fluids, which is characterized by the continuous creation and destruction of dense clusters due to self-sustained turbulence. This state arises due to the interplay of the self-advection of the aligned…

Soft Condensed Matter · Physics 2022-07-12 Vasco M. Worlitzer , Gil Ariel , Avraham Be'er , Holger Stark , Markus Bär , Sebastian Heidenreich

A common type of cytoskeletal morphology involves multiple converging microbutubules with their minus ends collected and stabilized by a microtubule organizing center (MTOC) in the interior of the cell. This arrangement enables the…

Cell Behavior · Quantitative Biology 2023-01-04 Niranjan Sarpangala , Brooke Randell , Ajay Gopinathan , Oleg Kogan

Molecular simulations provide a powerful means to unravel the complex relationships between network architecture and the mechanical response of polymer networks, with a particular emphasis on rupture and fracture phenomena. Although…

Soft Condensed Matter · Physics 2026-02-02 Yuichi Masubuchi , Takato Ishida , Yusuke Koide , Takashi Uneyama

Cluster media are dynamical, not static; observational evidence suggests they are turbulent. High-resolution simulations of the intracluster media (ICMs) and of idealized, similar media help us understand the complex physics and…

Cosmology and Nongalactic Astrophysics · Physics 2011-01-24 T. W. Jones , David H. Porter , Dongsu Ryu , Jungyeon Cho

Multiphase systems are ubiquitous in engineering, biology, and materials science, where understanding their complex interactions and rheological behavior is crucial for advancing applications ranging from emulsion stability to cellular…

Fluid Dynamics · Physics 2025-10-27 Andres Santiago Espinosa-Moreno , Nicolas Moreno , Marco Ellero

Nucleation is a key step in the synthesis of new material from solution. Well-established lattice-gas models can be used to gain insight into the basic physics of nucleation pathways involving a single nucleus type. In many situations a…

Statistical Mechanics · Physics 2023-01-04 Dipanjan Mandal , David Quigley

We here present a model of nonlinear dynamics of microtubules (MT) in the context of modified extended tanh-function (METHF) method. We rely on the ferroelectric model of MTs published earlier by Satari\'c et al [1] where the motion of MT…

Diffusion is a fundamental phenomenon that occurs ubiquitously in nature and remains the subject of continuous research interest. Understanding diffusion is a key to understanding leaving systems. In this Chapter, I discuss diffusion of…

Soft Condensed Matter · Physics 2018-10-15 Svyatoslav Kondrat

When very small particles are suspended in a fluid in motion, they tend to follow the flow. How such tracer particles are mixed, transported, and dispersed by turbulent flow has been successfully described by statistical models. Heavy…

Fluid Dynamics · Physics 2023-12-21 J. Bec , K. Gustavsson , B. Mehlig

We use optical trapping to continuously bend an isolated microtubule while simultaneously measuring the applied force and the resulting filament strain, thus allowing us to determine its elastic properties over a wide range of applied…

Biological Physics · Physics 2018-07-24 Edvin Memet , Feodor Hilitski , Margaret A Morris , Walter J Schwenger , Zvonimir Dogic , L Mahadevan

Cytoskeletons are self-organized networks based on polymerized proteins: actin, tubulin, and driven by motor proteins, such as myosin, kinesin and dynein. Their positive Darwinian evolution enables them to approach optimized functionality…

Other Quantitative Biology · Quantitative Biology 2020-08-21 J. C. Phillips

The transport of macromolecules, such as DNA, through the cytoskeleton is critical to wide-ranging cellular processes from cytoplasmic streaming to transcription. The rigidity and steric hindrances imparted by the network of filaments…

The internal dynamics of active gels, both in artificial (in-vitro) model systems and inside the cytoskeleton of living cells, has been extensively studied by experiments of recent years. These dynamics are probed using tracer particles…

Soft Condensed Matter · Physics 2015-07-28 E. Ben Isaac , É. Fodor , P. Visco , F. van Wijland , N. S. Gov

Meso-scale turbulence was originally observed experimentally in various suspensions of swimming bacteria, as well as in the collective motion of active colloids. The corresponding large-scale dynamical patterns were reproduced in a simple…

Soft Condensed Matter · Physics 2021-03-30 Vasco M. Worlitzer , Gil Ariel , Avraham Be'er , Holger Stark , Markus Bär , Sebastian Heidenreich

Proteins from the kinesin-8 family promote microtubule (MT) depolymerization, a process thought to be important for the control of microtubule length in living cells. In addition to this MT shortening activity, kinesin 8s are motors that…

Biological Physics · Physics 2015-05-13 L. E. Hough , Anne Schwabe , Matthew A. Glaser , J. Richard McIntosh , M. D. Betterton

An important aspect of astrophysical MHD turbulence research is developing diagnostics to connect simulations with the observable universe. Turbulent systems are by definition structurally complex in all fluid variables (density, velocity,…

Astrophysics · Physics 2007-05-23 Eve C. Ostriker

Microtubules (MTs) are important cytoskeletal structures, engaged in a number of specific cellular activities, including vesicular traffic, cell cyto-architecture and motility, cell division, and information processing within neuronal…

Subcellular Processes · Quantitative Biology 2007-05-23 Avner Priel , Arnolt J. Ramos , Jack A. Tuszynski , Horacio F. Cantiello

Particle-laden turbulence involves complex interactions between the dispersed and continuous phases. Given that particles can exhibit a wide range of properties, such as varying density, size, and shape, their interplay with the flow can…

Thermal shape fluctuations of grafted microtubules were studied using high resolution particle tracking of attached fluorescent beads. First mode relaxation times were extracted from the mean square displacement in the transverse…

Biomolecules · Quantitative Biology 2008-09-09 Katja M. Taute , Francesco Pampaloni , Erwin Frey , Ernst-Ludwig Florin

This paper exposes a novel exploratory formalism, which end goal is the numerical simulation of the dynamics of a cloud of particles weakly or strongly coupled with a turbulent fluid. Giventhe large panel of expertise of the list of…

Analysis of PDEs · Mathematics 2019-10-21 Ludovic Goudenège , Adam Larat , Julie Llobell , Marc Massot , David Mercier , Olivier Thomine , Aymeric Vié