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Multimorbidity in older adults is common, heterogeneous, and highly dynamic, and it is strongly associated with disability and increased healthcare utilization. However, existing approaches to studying multimorbidity trajectories are…

We develop and apply an approach for analyzing multi-curve data where each curve is driven by a latent state process. The state at any particular point determines a smooth function, forcing the individual curve to switch from one function…

Methodology · Statistics 2021-12-24 Camila P. E. de Souza , Nancy E. Heckman , Helena Xu

We consider a class of piecewise-deterministic Markov processes where the state evolves according to a linear dynamical system. This continuous time evolution is interspersed by discrete events that occur at random times and change (reset)…

Systems and Control · Computer Science 2017-11-15 Mohammad Soltani , Abhyudai Singh

The distribution of the "mixing time" or the "time to stationarity" in a discrete time irreducible Markov chain, starting in state i, can be defined as the number of trials to reach a state sampled from the stationary distribution of the…

Probability · Mathematics 2014-03-05 Jeffrey J. Hunter

Negative differential mobility is the phenomenon in which the velocity of a particle decreases when the force driving it increases. We study this phenomenon in Markov jump models where a particle moves in the presence of walls that act as…

Statistical Mechanics · Physics 2020-10-07 Gianluca Teza , Stefano Iubini , Marco Baiesi , Attilio L. Stella , Carlo Vanderzande

Muon spin relaxation is a powerful technique for probing static and dynamic local magnetic fields. The strong collision model, based on a Gaussian-Markovian process, is commonly used to account for dynamical effects. Yet, it remains limited…

Strongly Correlated Electrons · Physics 2025-09-01 Ola Kenji Forslund

This paper introduces a new approach of treating platoon systems using mean-variance control formulation. The underlying system is a controlled switching diffusion in which the random switching process is a continuous-time Markov chain.…

Optimization and Control · Mathematics 2014-01-22 Zhixin Yang , G. Yin , Le Yi Wang , Hongwei Zhang

Multistate Markov models are a canonical parametric approach for data modeling of observed or latent stochastic processes supported on a finite state space. Continuous-time Markov processes describe data that are observed irregularly over…

Stochastic Resonance in single voltage-dependent ion channels is investigated within a three state non-Markovian modeling of the ion channel conformational dynamics. In contrast to a two-state description one assumes the presence of an…

Biological Physics · Physics 2007-05-23 I. Goychuk , P. Hanggi , J. L. Vega , S. Miret-Artes

Motivated by a real failure dataset in a two-dimensional context, this paper presents an extension of the Markov modulated Poisson process (MMPP) to two dimensions. The one-dimensional MMPP has been proposed for the modeling of dependent…

Methodology · Statistics 2024-01-30 Yoel G. Yera , Rosa E. Lillo , Bo F. Nielsen , Pepa Ramírez-Cobo , Fabrizio Ruggeri

This paper deals with the analysis of input/output-to-state stability (IOSS) and construction of state-norm estimators for continuous-time switched nonlinear systems under restricted switching. Our contributions are twofold. First, given a…

Optimization and Control · Mathematics 2024-04-25 Atreyee Kundu

We explore a stochastic model that enables capturing external influences in two specific ways. The model allows for the expression of uncertainty in the parametrisation of the stochastic dynamics and incorporates patterns to account for…

Pricing of Securities · Quantitative Finance 2024-04-11 Felix L. Wolf , Griselda Deelstra , Lech A. Grzelak

Direct simulation of biomolecular dynamics in thermal equilibrium is challenging due to the metastable nature of conformation dynamics and the computational cost of molecular dynamics. Biased or enhanced sampling methods may improve the…

Chemical Physics · Physics 2015-06-12 Benjamin Trendelkamp-Schroer , Frank Noe

We present a new method for simulating Markovian jump processes with time-dependent transitions rates, which avoids the transformation of random numbers by inverting time integrals over the rates. It relies on constructing a sequence of…

Statistical Mechanics · Physics 2015-05-20 Viktor Holubec , Petr Chvosta , Mario Einax , Philipp Maass

Suppose X and Y are two independent irreducible Markov chains on n states. We consider the intersection time, which is the first time their trajectories intersect. We show for reversible and lazy chains that the total variation mixing time…

Probability · Mathematics 2014-12-30 Yuval Peres , Thomas Sauerwald , Perla Sousi , Alexandre Stauffer

Continuous-time multistate models are widely used for analyzing interval-censored data on disease progression over time. Sometimes, diseases manifest differently and what appears to be a coherent collection of symptoms is the expression of…

Methodology · Statistics 2024-10-08 Yidan Shi , Leilei Zeng , Mary E. Thompson , Suzanne L. Tyas

Accurately modeling crash severity on rural two-lane roads is essential for effective safety management, yet standard single level approaches often overlook unobserved heterogeneity across road segments. In this study, we analyze 19 956…

We study positive recurrence and transience of a two-station network in which the behavior of the server in each station is governed by a Markov chain with a finite number of server states; this service process can represent various service…

Probability · Mathematics 2013-08-29 Toshihisa Ozawa

Multi-state models are increasingly being used to model complex epidemiological and clinical outcomes over time. It is common to assume that the models are Markov, but the assumption can often be unrealistic. The Markov assumption is…

Methodology · Statistics 2020-08-26 N. Maltzahn , R. Hoff , O. O. Aalen , I. S. Mehlum , H. Putter , J. M. Gran

The present paper proposes a stochastic model of the traffic flow. This model has a discrete set of states and the continuous time. The model is a generalization of the discrete stochastis model that has been considered in a previous paper…

Other Condensed Matter · Physics 2007-05-23 A. P. Buslaev , A. G. Tatashev , M. V. Yashina
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