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Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

Cell Behavior · Quantitative Biology 2015-12-09 Gabriele Micali , Robert G. Endres

Growing anthropogenic pressures have increased the need for robust predictive models. Meeting this demand requires approaches that can handle bigger data to yield forecasts that capture the variability and underlying uncertainty of…

Quantitative Methods · Quantitative Biology 2024-08-06 EM Wolkovich , T Jonathan Davies , William D Pearse , Michael Betancourt

The interaction mechanisms of water with nanoscale geometries remain poorly understood. This study focuses on behaviour of water clusters under varying external electric fields with a particular focus on molecular ferroelectric devices. We…

In this world of terrorism, it is very important to know the network of individual suspects. It is also important to analyze the attributes of members of a network and the relationships that exist between them either directly or indirectly.…

Computers and Society · Computer Science 2013-07-31 Quist-Aphetsi Kester

A Bayesian approach is developed to analyze change points in multivariate time series and space-time data. The methodology is used to assess the impact of extended inundation on the ecosystem of the Gulf Plains bioregion in northern…

Methodology · Statistics 2013-06-21 Chris Strickland , Robert Burdett , Robert Denham , Robert Kohn , Kerrie Mengersen

This is the first paper presenting our long-term project aimed at studying the nature of bulges through the analysis of their stellar population gradients. We present deep spectroscopic observations along the minor axis and the data…

Astrophysics · Physics 2009-11-13 J. Gorgas , P. Jablonka , P. Goudfrooij

Multifields datasets are common in a large number of research and engineering applications of computational science. The effective visualization of the corresponding datasets can facilitate their analysis by elucidating the complex and…

Graphics · Computer Science 2022-03-23 Zi'ang Ding , Xavier Tricoche

Our interest is in multiplex network data with multiple network samples observed across the same set of nodes. Examples originate from a variety of fields, including brain connectivity, international trade networks, and social networks,…

Methodology · Statistics 2026-04-21 Yuren Zhou , Yuqi Gu , David B. Dunson

While "complexity science" has achieved significant successes in several interdisciplinary fields such as economics and biology, it is only a very recent observation that legal systems -- from the way legal texts are drafted and connected…

Physics and Society · Physics 2025-01-08 Pierpaolo Vivo , Daniel M. Katz , J. B. Ruhl

In today's data-driven digital era, the amount as well as complexity, such as multi-view, non-Euclidean, and multi-relational, of the collected data are growing exponentially or even faster. Clustering, which unsupervisely extracts valid…

Machine Learning · Computer Science 2025-01-10 Zhao Kang , Xuanting Xie , Bingheng Li , Erlin Pan

By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

Applications · Statistics 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

Microbiome compositional data are often high-dimensional, sparse, and exhibit pervasive cross-sample heterogeneity. Generative modeling is a popular approach to analyze such data, and effective generative models must accurately characterize…

Methodology · Statistics 2025-01-03 Zhuoqun Wang , Jialiang Mao , Li Ma

Network theory has proven to be a powerful tool in describing and analyzing systems by modelling the relations between their constituent objects. In recent years great progress has been made by augmenting `traditional' network theory.…

Data Analysis, Statistics and Probability · Physics 2016-06-03 Dominik Traxl , Niklas Boers , Jürgen Kurths

Clays control carbon, water and nutrient transport in the lithosphere, promote cloud formation5 and lubricate fault slip through interactions among hydrated mineral interfaces. Clay mineral properties are difficult to model because their…

Anthropogenic pollution of hydrological systems affects diverse communities and ecosystems around the world. Data analytics and modeling tools play a key role in fighting this challenge, as they can help identify key sources as well as…

Machine Learning · Computer Science 2023-09-26 David L. Cole , Gerardo J. Ruiz-Mercado , Victor M. Zavala

We introduce Forman-Ricci curvature and its corresponding flow as characteristics for complex networks attempting to extend the common approach of node-based network analysis by edge-based characteristics. Following a theoretical…

Discrete Mathematics · Computer Science 2016-10-19 Melanie Weber , Emil Saucan , Jürgen Jost

Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

An understanding of the hydrophobicity of complex heterogeneous molecular assemblies is crucial to characterize and predict interactions between biomolecules. As such, uncovering the subtleties of assembly processes hinges on an accurate…

Soft Condensed Matter · Physics 2015-02-20 Richard C. Remsing , John D. Weeks

Understanding how microbes interact with each other is key to revealing the underlying role that microorganisms play in the host or environment and to identifying microorganisms as an agent that can potentially alter the host or…

Applications · Statistics 2022-07-05 Chuan Tian , Duo Jiang , Austin Hammer , Thomas Sharpton , Yuan Jiang

We consider the challenges that arise when fitting complex ecological models to 'large' data sets. In particular, we focus on random effect models which are commonly used to describe individual heterogeneity, often present in ecological…

Methodology · Statistics 2022-05-17 Ruth King , Blanca Sarzo , Víctor Elvira
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