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Parameter estimation is a major challenge in computational modeling of biological processes. This is especially the case in image-based modeling where the inherently quantitative output of the model is measured against image data, which is…

Quantitative Methods · Quantitative Biology 2018-07-27 Diana Barac , Michael D. Multerer , Dagmar Iber

This work concerns the estimation of multidimensional nonlinear regression models using multilayer perceptrons (MLPs). The main problem with such models is that we need to know the covariance matrix of the noise to get an optimal estimator.…

Statistics Theory · Mathematics 2008-02-22 Joseph Rynkiewicz

This work investigates the task of estimating a real valued parameter vector based on complex valued measurements in a classical set-up. The application of standard estimators in general results in complex valued estimates of the real…

Statistics Theory · Mathematics 2017-05-01 Oliver Lang , Mario Huemer

Nonlinear regression methods, such as local optimization algorithms, are widely used in the extraction of nanostructure profile parameters in optical scatterometry. The success of local optimization algorithms heavily relies on the…

Optimization and Control · Mathematics 2019-05-17 Jinlong Zhu , Hao Jiang , Chuanwei Zhang , Xiuguo Chen , Shiyuan Liu

Dimensionality reduction is a fundamental task in modern data science. Several projection methods specifically tailored to take into account the non-linearity of the data via local embeddings have been proposed. Such methods are often based…

Machine Learning · Statistics 2026-01-28 Antonio Di Noia , Federico Ravenda , Antonietta Mira

We consider in this paper the problem of estimating a parameter matrix from observations which are affected by two types of noise components: (i) a sparse noise sequence which, whenever nonzero can have arbitrarily large amplitude (ii) and…

Systems and Control · Computer Science 2017-11-07 Laurent Bako

Spatial generalized linear mixed models (SGLMMs) are popular and flexible models for non-Gaussian spatial data. They are useful for spatial interpolations as well as for fitting regression models that account for spatial dependence, and are…

Methodology · Statistics 2021-10-26 Yawen Guan , Murali Haran

In recent years, a rich variety of regularization procedures have been proposed for high dimensional regression problems. However, tuning parameter choice and computational efficiency in ultra-high dimensional problems remain vexing issues.…

Computation · Statistics 2012-01-18 Hua Zhou , Artin Armagan , David B. Dunson

This paper evaluates the performance of algorithms suitable to process the measurements from two laser beam metrology systems, in particular with reference to the Gaia Basic Angle Monitoring device. The system and signal characteristics are…

Instrumentation and Methods for Astrophysics · Physics 2014-08-05 Mario Gai , Alberto Riva , Deborah Busonero , Raffaella Buzzi , Federico Russo

We consider approximate maximum likelihood parameter estimation in nonlinear state-space models. We discuss both direct optimization of the likelihood and expectation--maximization (EM). For EM, we also give closed-form expressions for the…

Methodology · Statistics 2015-11-03 Juho Kokkala , Arno Solin , Simo Särkkä

The standard way to estimate the parameters $\Theta_\text{SEIR}$ (e.g., the transmission rate $\beta$) of an SEIR model is to use grid search, where simulations are performed on each set of parameters, and the parameter set leading to the…

Machine Learning · Statistics 2021-06-01 Chun Fan , Yuxian Meng , Xiaofei Sun , Fei Wu , Tianwei Zhang , Jiwei Li

Generalized linear models (GLMs) are fundamental tools for statistical modeling, with maximum likelihood estimation (MLE) serving as the classical approach for parameter inference. While MLE performs well for canonical GLMs, it can become…

Methodology · Statistics 2026-03-03 Linglingzhi Zhu , Jonghyeok Lee , Yao Xie

We present a neural net algorithm for parameter estimation in the context of large cosmological data sets. Cosmological data sets present a particular challenge to pattern-recognition algorithms since the input patterns (galaxy redshift…

Astrophysics · Physics 2007-05-23 Nicholas G. Phillips , A. Kogut

Identification of model parameters in computer simulations is an important topic in computer experiments. We propose a new method, called the projected kernel calibration method, to estimate these model parameters. The proposed method is…

Methodology · Statistics 2017-05-10 Rui Tuo

Highly robust and efficient estimators for the generalized linear model with a dispersion parameter are proposed. The estimators are based on three steps. In the first step the maximum rank correlation estimator is used to consistently…

Methodology · Statistics 2017-03-29 Michael Amiguet , Alfio Marazzi , Marina Valdora , Victor Yohai

Latent variable models have been playing a central role in psychometrics and related fields. In many modern applications, the inference based on latent variable models involves one or several of the following features: (1) the presence of…

Methodology · Statistics 2025-01-08 Siliang Zhang , Yunxiao Chen

When determining the parameters of a parametric planar shape based on a single low-resolution image, common estimation paradigms lead to inaccurate parameter estimates. The reason behind poor estimation results is that standard estimation…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Wojciech Chojnacki , Zygmunt L. Szpak

The linear model uses the space defined by the input to project the target or desired signal and find the optimal set of model parameters. When the problem is nonlinear, the adaption requires nonlinear models for good performance, but it…

Machine Learning · Computer Science 2018-02-05 Zhengda Qin , Badong Chen , Nanning Zheng , Jose C. Principe

Recently, a framework for application-oriented optimal experiment design has been introduced. In this context, the distance of the estimated system from the true one is measured in terms of a particular end-performance metric. This…

Information Theory · Computer Science 2015-07-28 Dimitrios Katselis , Cristian R. Rojas , Carolyn L. Beck

This paper discusses the problem of adaptive estimation of a univariate object like the value of a regression function at a given point or a linear functional in a linear inverse problem. We consider an adaptive procedure originated from…

Statistics Theory · Mathematics 2009-08-26 Vladimir Spokoiny , Céline Vial