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Neural architecture search (NAS) is gaining more and more attention in recent years due to its flexibility and remarkable capability to reduce the burden of neural network design. To achieve better performance, however, the searching…

Machine Learning · Computer Science 2022-05-23 Yijun Bian , Qingquan Song , Mengnan Du , Jun Yao , Huanhuan Chen , Xia Hu

Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of protein sequences, but structure is critical for…

Machine Learning · Computer Science 2019-10-17 Tristan Bepler , Bonnie Berger

Cross-lingual embeddings aim to represent words in multiple languages in a shared vector space by capturing semantic similarities across languages. They are a crucial component for scaling tasks to multiple languages by transferring…

Computation and Language · Computer Science 2019-07-10 Lena Shakurova , Beata Nyari , Chao Li , Mihai Rotaru

Purpose: This study aimed to enhance protein sequence classification using natural language processing (NLP) techniques while addressing the impact of sequence similarity on model performance. We compared various machine learning and deep…

Quantitative Methods · Quantitative Biology 2025-05-26 Huma Perveen , Julie Weeds

A seed in a word is a relaxed version of a period in which the occurrences of the repeating subword may overlap. We show a linear-time algorithm computing a linear-size representation of all the seeds of a word (the number of seeds might be…

Data Structures and Algorithms · Computer Science 2019-03-15 Tomasz Kociumaka , Marcin Kubica , Jakub Radoszewski , Wojciech Rytter , Tomasz Walen

Medical systematic review query formulation is a highly complex task done by trained information specialists. Complexity comes from the reliance on lengthy Boolean queries, which express a detailed research question. To aid query…

Information Retrieval · Computer Science 2022-04-26 Shuai Wang , Harrisen Scells , Justin Clark , Bevan Koopman , Guido Zuccon

The study of biological processes can greatly benefit from tools that automatically predict gene functions or directly cluster genes based on shared functionality. Existing data mining methods predict protein functionality by exploiting…

Machine Learning · Computer Science 2020-11-20 Kaiyu Shen , Razvan Bunescu , Sarah E. Wyatt

Generative models emerge as promising candidates for novel sequence-data driven approaches to protein design, and for the extraction of structural and functional information about proteins deeply hidden in rapidly growing sequence…

Biomolecules · Quantitative Biology 2021-11-10 Jeanne Trinquier , Guido Uguzzoni , Andrea Pagnani , Francesco Zamponi , Martin Weigt

A new Chase-type soft-decision decoding algorithm for Reed-Solomon codes is proposed, referred to as tree-based Chase-type algorithm}. The proposed tree-based Chase-type algorithm takes the set of all vectors as the set of testing patterns,…

Information Theory · Computer Science 2022-05-27 Siyun Tang , Suihua Cai , Xiao Ma Member

GNAS (Graph Neural Architecture Search) has demonstrated great effectiveness in automatically designing the optimal graph neural architectures for multiple downstream tasks, such as node classification and link prediction. However, most…

Machine Learning · Computer Science 2024-12-04 Guanghui Zhu , Zipeng Ji , Jingyan Chen , Limin Wang , Chunfeng Yuan , Yihua Huang

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

Clustering genotypes based upon their phenotypic characteristics is used to obtain diverse sets of parents that are useful in their breeding programs. The Hierarchical Clustering (HC) algorithm is the current standard in clustering of…

Machine Learning · Computer Science 2020-09-22 Aditya A. Shastri , Kapil Ahuja , Milind B. Ratnaparkhe , Yann Busnel

Multiple kernel learning algorithms are proposed to combine kernels in order to obtain a better similarity measure or to integrate feature representations coming from different data sources. Most of the previous research on such methods is…

Machine Learning · Computer Science 2012-07-03 Mehmet Gonen

Seed phenotyping is the idea of analyzing the morphometric characteristics of a seed to predict the behavior of the seed in terms of development, tolerance and yield in various environmental conditions. The focus of the work is the…

Computer Vision and Pattern Recognition · Computer Science 2020-12-25 Venkat Margapuri , Mitchell Neilsen

Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…

Machine Learning · Computer Science 2019-09-17 James K. Senter , Taylor M. Royalty , Andrew D. Steen , Amir Sadovnik

We propose Hercules, a parallel tree-based technique for exact similarity search on massive disk-based data series collections. We present novel index construction and query answering algorithms that leverage different summarization…

Databases · Computer Science 2022-12-29 Karima Echihabi , Panagiota Fatourou , Kostas Zoumpatianos , Themis Palpanas , Houda Benbrahim

We are concerned with the problem of designing large families of subsets over a common labeled ground set that have small pairwise intersections and the property that the maximum discrepancy of the label values within each of the sets is…

Information Theory · Computer Science 2019-01-18 R. Gabrys , H. S. Dau , C. J. Colbourn , O. Milenkovic

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Graph matching aims to find the latent vertex correspondence between two edge-correlated graphs and has found numerous applications across different fields. In this paper, we study a seeded graph matching problem, which assumes that a set…

Data Structures and Algorithms · Computer Science 2021-01-06 Liren Yu , Jiaming Xu , Xiaojun Lin

Highly accurate biomolecular structure prediction is a key component of developing biomolecular foundation models, and one of the most critical aspects of building foundation models is identifying the recipes for scaling the model. In this…

Biomolecules · Quantitative Biology 2026-01-02 Yi Zhou , Chan Lu , Yiming Ma , Wei Qu , Fei Ye , Kexin Zhang , Lan Wang , Minrui Gui , Quanquan Gu
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