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Mathematical modeling and analysis can provide insight on the dynamics of ecosystems which maintain biodiversity in the face of competitive and prey-predator interactions. Of primary interests are the underlying structure and features which…

Populations and Evolution · Quantitative Biology 2017-01-03 Cameron J. Browne

In [Math. Comput. Sci. 12 (2018), no. 2, 111--127], a delayed model describing the dynamics of the Human Immunodeficiency Virus (HIV) with Cytotoxic T Lymphocytes (CTL) immune response is investigated by Allali, Harroudi and Torres. Here,…

Dynamical Systems · Mathematics 2022-10-03 Sandra Vaz , Delfim F. M. Torres

In this paper, we investigate global dynamics for a system of delay differential equations which describes a virus-immune interaction in \textit{vivo}. The model has two distributed time delays describing time needed for infection of cell…

Dynamical Systems · Mathematics 2010-08-17 Yukihiko Nakata

In this paper, we present the global analysis of a HCV model under therapy. We prove that the solutions with positive initial values are global, positive, bounded and not display periodic orbits. In addition, we show that the model is…

Populations and Evolution · Quantitative Biology 2019-05-09 Alexis Nangue

In this paper, a mathematical analysis of the global dynamics of a partial differential equation viral infection cellular model is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both…

Analysis of PDEs · Mathematics 2021-11-08 Alexis Nangue , Bruno Nde Tchiffo

The host immune response can often efficiently suppress a virus infection, which may lead to selection for immune-resistant viral variants within the host. For example, during HIV infection, an array of CTL immune response populations…

Populations and Evolution · Quantitative Biology 2018-02-23 Cameron J. Browne , Hal L. Smith

A virus dynamics model with intracellular state-dependent delay and nonlinear infection rate of Beddington-DeAngelis functional response is studied. The technique of Lyapunov functionals is used to analyze stability of an interior infection…

Dynamical Systems · Mathematics 2017-06-29 Alexander Rezounenko

The aims of this work is to analyse of the global stability of the extended model of hepatitis C virus(HCV) infection with cellular proliferation, spontaneous cure and hepatocyte homeostasis. We first give general information about…

Dynamical Systems · Mathematics 2019-05-08 Alexis Nangue , Cyprien Fokoue , Raoue Poumeni

We investigate global stability properties of a HIV/AIDS population model with constant recruitment rate, mass action incidence, and variable population size. Existence and uniqueness results for disease-free and endemic equilibrium points…

Populations and Evolution · Quantitative Biology 2017-07-05 Cristiana J. Silva , Delfim F. M. Torres

We consider within-host virus models with more than one strain and allow mutation between the strains. If there is no mutation, a Lyapunov function establishes global stability of the steady state corresponding to the fittest strain. For…

Cell Behavior · Quantitative Biology 2007-08-01 Patrick De Leenheer , Sergei S. Pilyugin

A retrovirus dynamic model is proposed. We pay attention to the case when viral pathogenicity is low and the infected cells are able to reproduce. Using Lyapunov function method we study stability properties of an inner equilibrium of the…

Dynamical Systems · Mathematics 2019-01-01 Andrei Korobeinikov , Alexander Rezounenko

This research gives a thorough examination of an HIV infection model that includes quiescent cells and immune response dynamics in the host. The model, represented by a system of ordinary differential equations, captures the complex…

Populations and Evolution · Quantitative Biology 2025-03-04 Ibrahim Nali , Attila Dénes , Abdessamad Tridane , Xueyong Zhou

We investigate the global dynamics of a renewal-type epidemic model with variable susceptibility. We show that in this extended model there exists a unique endemic equilibrium and prove that it is globally asymptotically stable when $R_0 >…

Dynamical Systems · Mathematics 2020-07-24 Michael T. Meehan , Daniel G. Cocks , Emma S. McBryde

In this paper, we develop a dynamic model of HIV infection that incorporates latent hosts, cytotoxic T lymphocyte (CTL) immunity, saturated incidence rates, and two transmission mechanisms: virus-to-cell and cell-to-cell transmission. The…

Dynamical Systems · Mathematics 2025-11-25 Songbo Hou , Xinxin Tian

Considering the propagation characteristics of COVID-19 in different regions, the dynamics analysis and numerical demonstration of long-term and short-term models of COVID-19 are carried out, respectively. The long-term model is devoted to…

Dynamical Systems · Mathematics 2022-11-08 Songbai Guo , Yuling Xue , Xiliang Li , Zuohuan Zheng

We will study a mathematical model of the human immunodeficiency virus (HIV) infection in the presence of combination therapy that includes within-host infectious dynamics. The deterministic model requires us to analyze asymptotic stability…

Populations and Evolution · Quantitative Biology 2017-09-04 Majid Jaberi Douraki

Transmission dynamics of infectious diseases are often studied using compartmental mathematical models, which are commonly represented as systems of autonomous ordinary differential equations. A key step in the analysis of such models is to…

Populations and Evolution · Quantitative Biology 2025-12-15 David J. D. Earn , C. Connell McCluskey

The global stability of the nonhomogeneous positive steady state solution to a diffusive Holling-Tanner predator-prey model in a heterogeneous environment is proved by using a newly constructed Lyapunov function and estimates of nonconstant…

Analysis of PDEs · Mathematics 2020-07-31 Wenjie Ni , Junping Shi , Mingxin Wang

A class of chemical reaction networks is described with the property that each positive equilibrium is locally asymptotically stable relative to its stoichiometry class, an invariant subspace on which it lies. The reaction systems treated…

Dynamical Systems · Mathematics 2013-04-11 Pete Donnell , Murad Banaji

A class of reaction-diffusion virus dynamics models with intracellular state-dependent delay and a general non-linear infection rate functional response is investigated. We are interested in classical solutions with Lipschitz in-time…

Dynamical Systems · Mathematics 2019-01-01 Alexander Rezounenko
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