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The slime mould Physarum polycephalum displays adaptive transport dynamics and network formation that have inspired its use as a model of biological computation. We develop a Lagrangian formulation of Physarum's adaptive dynamics on…

Neurons and Cognition · Quantitative Biology 2025-11-12 Ricard Solé , Jordi Pla-Mauri

Swimmers and self-propelled particles are physical models for the collective behaviour and motility of a wide variety of living systems, such as bacteria colonies, bird flocks and fish schools. Such artificial active materials are amenable…

Learning in living organisms is typically associated with networks of neurons. The use of large numbers of adjustable units has also been a crucial factor in the continued success of artificial neural networks. In light of the complexity of…

Neurons and Cognition · Quantitative Biology 2024-05-10 Matthew Smart , Stanislav Y. Shvartsman , Martin Mönnigmann

Grid cells in the medial entorhinal cortex (MEC) of the mammalian brain exhibit a strikingly regular hexagonal firing field over space. These cells are learned after birth and are thought to support spatial navigation but also more abstract…

Neurons and Cognition · Quantitative Biology 2024-10-07 Mufeng Tang , Helen Barron , Rafal Bogacz

Bacteria live in environments that are continuously fluctuating and changing. Exploiting any predictability of such fluctuations can lead to an increased fitness. On longer timescales bacteria can "learn" the structure of these fluctuations…

Cell Behavior · Quantitative Biology 2021-01-05 Stefan Landmann , Caroline M. Holmes , Mikhail Tikhonov

The neural implementation of operant conditioning with few trials is unclear. We propose a Hippocampus-Inspired Cognitive Architecture (HICA) as a neural mechanism for operant conditioning. HICA explains a learning mechanism in which agents…

Artificial Intelligence · Computer Science 2022-12-19 Deokgun Park , Md Ashaduzzaman Rubel Mondol , SM Mazharul Islam , Aishwarya Pothula

Spike-based learning with memristive devices in neuromorphic computing architectures typically uses learning circuits that require overlapping pulses from pre- and post-synaptic nodes. This imposes severe constraints on the length of the…

Emerging Technologies · Computer Science 2017-11-07 Manu V Nair , Lorenz K. Muller , Giacomo Indiveri

Based on the oligomer-world hypothesis we propose an abstract model where the molecular recognition among oligomers is described in the shape space. The origin of life in the oligomer world is regarded as the establishment of a metabolic…

Subcellular Processes · Quantitative Biology 2012-09-21 Tomoaki Nishio , Osamu Narikiyo

The behavior of living systems is based on the experience they gained through their interactions with the environment [1]. This experience is stored in the complex biochemical networks of cells and organisms to provide a relationship…

Soft Condensed Matter · Physics 2022-02-14 Santiago Muiños-Landin , Keyan Ghazi-Zahedi , Frank Cichos

This paper is a completion of an earlier model proposed by us. In the model different memories are attached at cell surface determinants which are the result of DNA recombination. Our earlier experiments strongly suggest that DNA…

Neurons and Cognition · Quantitative Biology 2014-01-21 Axel Dietrich , Willem Been

Memristors are promising next-generation memory candidates that are nonvolatile, possess low power requirements and are capable of nanoscale fabrication. In this article we physically realise and describe the use of organic memristors in…

Emerging Technologies · Computer Science 2012-12-17 Victor Erokhin , Gerard David Howard , Andrew Adamatzky

Eukaryotic adaptation pathways operate within wide-ranging environmental conditions without stimulus saturation. Despite numerous differences in the adaptation mechanisms employed by bacteria and eukaryotes, all require energy consumption.…

Cell Behavior · Quantitative Biology 2014-03-05 Giovanna De Palo , Robert G. Endres

Adaptive reasoning enables humans to flexibly adjust inference strategies when environmental rules or contexts change, yet its underlying neural dynamics remain unclear. This study investigated the neurophysiological mechanisms of adaptive…

Artificial Intelligence · Computer Science 2025-11-12 Jun-Young Kim , Young-Seok Kweon , Gi-Hwan Shin , Seong-Whan Lee

We introduce and study a learning theory which is roughly automatic, that is, it does not require but a minimum of initial programming, and is based on the potential computational phenomenon of self-reference, (i.e. the potential ability of…

Logic in Computer Science · Computer Science 2023-04-25 A. D. Arvanitakis

We present a simple model that describes the motion of a single chemotactic cell exposed to a traveling wave of the chemoattractant. The model incorporates two types of responses to stimulation by the chemoattractant, i.e., change in…

Biological Physics · Physics 2011-10-26 Masatomo Iwasa , Ryosuke Ishiwata

Little is known theoretically about the associative memory capabilities of neural networks in which information is encoded not only in the mean firing rate but also in the timing of firings. Particularly, in the case that the fraction of…

Disordered Systems and Neural Networks · Physics 2009-10-31 Toshio Aoyagi , Masaki Nomura

It is noticed that the inductive and capacitive features of the memristor reflect (and are a quintessence of) such features of any resistor. The very presence in the resistive characteristic v = f(i) of the voltage and current state…

Emerging Technologies · Computer Science 2015-01-13 Emanuel Gluskin

Adaptation to environmental change is a common property of biological systems. Cells initially respond to external changes in the environment, but after some time, they regain their original state. By considering an element consisting of…

Biological Physics · Physics 2015-05-13 Masayo Inoue , Kunihiko Kaneko

Comprehensive understanding of the world's most energy efficient powerful computer, the human brain, is an elusive scientific issue. Still, already gained knowledge indicates memristors can be used as a building block to model the brain. At…

Applied Physics · Physics 2017-06-20 Mohamed T. Ghoneim , Muhammad M. Hussain

Highly accurate and predictive models of resistive switching devices are needed to enable future memory and logic design. Widely used is the memristive modeling approach considering resistive switches as dynamical systems. Here we introduce…

Emerging Technologies · Computer Science 2015-03-02 E. Linn , A. Siemon , R. Waser , S. Menzel
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