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This paper analyzes the role of neutral viruses in the phenomenon of local immunodeficiency. We show that, even in the absence of altruistic viruses, neutral viruses can support the existence of persistent viruses, and thus local…

Dynamical Systems · Mathematics 2020-08-18 Leonid Bunimovich , Longmei Shu

We introduce a minimal multiscale framework that links within-host virus dynamics to population-level SIRS epidemiology through explicit, bidirectional coupling. At the microscopic layer, a two variant quasispecies (master and mutant…

Dynamical Systems · Mathematics 2026-01-28 Juan C. Muñoz-Sánchez , J. Tomás Lázaro , Josep Sardanyés , Santiago F. Elena

Viruses can amplify their genomes following different replication modes (RMs) ranging from the stamping machine replication (SMR) model to the geometric replication (GR) model. Different RMs are expected to produce different evolutionary…

Populations and Evolution · Quantitative Biology 2014-11-27 Josep Sardanyés

We investigate mechanisms of the typically observed recoverable prevalence in epidemic spreading. Assuming the time-independent connectivity correlations, we analyze the dynamics of spreading on linearly growing scale-free (SF) networks,…

Statistical Mechanics · Physics 2007-05-23 Yukio Hayashi

We use a multitype continuous time Markov branching process model to describe the dynamics of the spread of parasites of two types that can mutate into each other in a common host population. Instead of using a single virulence…

Probability · Mathematics 2011-09-02 Konstantin Borovkov , Robert Day , Timothy Rice

The paper explores the influence of harvesting (or culling) on the outcome of the competition of two species in a spatially heterogeneous environment. The harvesting effort is assumed to be proportional to the space-dependent intrinsic…

Dynamical Systems · Mathematics 2019-05-01 Elena Braverman , Ilia Ilmer

When three species compete cyclically in a well-mixed, stochastic system of $N$ individuals, extinction is known to typically occur at times scaling as the system size $N$. This happens, for example, in rock-paper-scissors games or…

Physics and Society · Physics 2019-02-20 Kevin E. Bassler , Erwin Frey , R. K. P. Zia

This paper is concerned with a diffusive Lotka-Volterra type competition system with a free boundary in one space dimension. Such a system may be used to describe the invasion of a new species into the habitat of a native competitor. We…

Analysis of PDEs · Mathematics 2017-10-17 Zhiguo Wang , Hua Nie , Yihong Du

In this paper, we extend a model of host-parasite co-evolution to incorporate the semi-conservative nature of DNA replication for both the host and the parasite. We find that the optimal mutation rate for the semi-conservative and…

Populations and Evolution · Quantitative Biology 2009-11-10 Yisroel Brumer , Eugene I. Shakhnovich

Compartmentalization of self-replicating molecules (templates) in protocells is a necessary step towards the evolution of modern cells. However, coexistence between distinct template types inside a protocell can be achieved only if there is…

Biological Physics · Physics 2013-02-19 J. F. Fontanari , M. Serva

We introduce a generalized version of the frog model to describe the invasion of a parasite population in a spatially structured immobile host population with host immunity on the integer line. Parasites move according to simple symmetric…

Probability · Mathematics 2025-02-17 Sascha Franck , Cornelia Pokalyuk

We study the early stages of viral infection, and the distribution of times to obtain a persistent infection. The virus population proliferates by entering and reproducing inside a target cell until a sufficient number of new virus…

Populations and Evolution · Quantitative Biology 2019-07-11 Carmel Sagi , Michael Assaf

This paper investigates the competition of two species in a heterogeneous environment subject to the effect of harvesting. The most realistic harvesting case is connected with the intrinsic growth rate, and the harvesting functions are…

Coexistence of individuals with different species or phenotypes is often found in nature in spite of competition between them. Stable coexistence of multiple types of individuals have implications for maintenance of ecological biodiversity…

Disordered Systems and Neural Networks · Physics 2007-05-23 Naoki Masuda , Norio Konno

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

Populations and Evolution · Quantitative Biology 2026-05-13 Seong Jun Park

We consider the classical two-species Lotka-Volterra competition-diffusion system in the strong-weak competition case. When the corresponding minimal speed of the traveling waves is not linear determined, we establish the precise asymptotic…

Analysis of PDEs · Mathematics 2022-01-13 Chang-Hong Wu , Dongyuan Xiao , Maolin Zhou

The coexistence of different viral strains (quasispecies) within the same host are nowadays observed for a growing number of viruses, most notably HIV, Marburg and Ebola, but the conditions for the formation and survival of new strains have…

Populations and Evolution · Quantitative Biology 2008-01-20 Franco Bagnoli , Pietro Lio' , Luca Sguanci

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

Statistical Mechanics · Physics 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

The current paper is concerned with the existence of spreading speeds and linear determinacy for two species competition systems with nonlocal dispersal in time and space periodic habitats. The notion of spreading speed intervals for such a…

Dynamical Systems · Mathematics 2015-12-01 Liang Kong , Nar Rawal , Wenxian Shen

We introduce and investigate an SIS-type model for the spread of an infectious disease, where the infected population is structured with respect to the different strain of the virus/bacteria they are carrying. Our aim is to capture the…

Analysis of PDEs · Mathematics 2019-03-25 Àngel Calsina , József Z. Farkas
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