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Brain rhythms emerge as a result of synchronization among interconnected spiking neurons. Key properties of such rhythms can be gleaned from the phase-resetting curve (PRC). Inferring the macroscopic PRC and developing a systematic phase…

Neurons and Cognition · Quantitative Biology 2022-10-12 Gregory Dumont , Alberto Pérez-Cervera , Boris Gutkin

Despite their significant functional roles, beta-band oscillations are least understood. Synchronization in neuronal networks have attracted much attention in recent years with the main focus on transition type. Whether one obtains…

Adaptation and Self-Organizing Systems · Physics 2018-10-22 Mahsa Khoshkhou , Afshin Montakhab

We have studied neuronal synchronisation in a random network of adaptive exponential integrate-and-fire neurons. We study how spiking or bursting synchronous behaviour appears as a function of the coupling strength and the probability of…

Pulse-coupled threshold units serve as paradigmatic models for a wide range of complex systems. When the state variable of a unit crosses a threshold, the unit sends a pulse that is received by other units, thereby mediating the…

Dynamical Systems · Mathematics 2010-06-04 Christoph Kirst , Marc Timme

Currently we routinely develop a complex neuronal network to explain observed but often paradoxical phenomena based upon biological recordings. Here we present a general approach to demonstrate how to mathematically tackle such a complex…

Quantitative Methods · Quantitative Biology 2015-06-03 Yu Wu , Wenlian Lu , Wei Lin , Gareth Leng , Jianfeng Feng

The background activity of a cortical neural network is modeled by a homogeneous integrate-and-fire network with unreliable inhibitory synapses. Numerical and analytical calculations show that the network relaxes into a stationary state of…

Disordered Systems and Neural Networks · Physics 2007-05-23 Wolfgang Kinzel

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

Neurons and Cognition · Quantitative Biology 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

Neurons and Cognition · Quantitative Biology 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

Understanding complex systems which exhibit desynchronization as an emergent property should have important implications, particularly in treating neurological disorders and designing efficient communication networks. Here were demonstrate…

Mathematical Physics · Physics 2012-11-06 J. Borresen , D. Broomhead

What input signals will lead to synchrony vs. desynchrony in a group of biological oscillators? This question connects with both classical dynamical systems analyses of entrainment and phase locking and with emerging studies of stimulation…

Dynamical Systems · Mathematics 2015-03-17 Guillaume Lajoie , Eric Shea-Brown

Bursting neurons fire rapid sequences of action potential spikes followed by a quiescent period. The basic dynamical mechanism of bursting is the slow currents that modulate a fast spiking activity caused by rapid ionic currents. Minimal…

Chaotic Dynamics · Physics 2015-02-16 Fabiano A. S. Ferrari , Ricardo L. Viana , Sérgio R. Lopes , Ruedi Stoop

Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that…

Neurons and Cognition · Quantitative Biology 2016-10-07 Christian Geier , Alexander Rothkegel , Christian E. Elger , Klaus Lehnertz

Networks of fast-spiking interneurons are crucial for the generation of neural oscillations in the brain. Here we study the synchronous behavior of interneuronal networks that are coupled by delayed inhibitory and fast electrical synapses.…

Neurons and Cognition · Quantitative Biology 2012-06-22 Daqing Guo , Qingyun Wang , Matjaz Perc

We present a formal, mathematical foundation for modeling and reasoning about the behavior of $synchronous$, $stochastic$ $Spiking$ $Neural$ $Networks$ $(SNNs)$, which have been widely used in studies of neural computation. Our approach…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-10-10 Nancy Lynch , Cameron Musco

Biologically inspired spiking neural networks (SNNs) are widely used to realize ultralow-power energy consumption. However, deep SNNs are not easy to train due to the excessive firing of spiking neurons in the hidden layers. To tackle this…

Neural and Evolutionary Computing · Computer Science 2022-03-04 Shin-ichi Ikegawa , Ryuji Saiin , Yoshihide Sawada , Naotake Natori

Neural synchronization is believed to be critical for many brain functions. It frequently exhibits temporal variability, but it is not known if this variability has a specific temporal patterning. This study explores these…

Neurons and Cognition · Quantitative Biology 2013-03-11 Sungwoo Ahn , Leonid L. Rubchinsky

Inhibitory interneurons, ubiquitous in the central nervous system, form networks connected through both chemical synapses and gap junctions. These networks are essential for regulating the activity of principal neurons, especially by…

Neurons and Cognition · Quantitative Biology 2025-05-09 Hélène Todd , Mathieu Desroches , Alex Cayco-Gajic , Boris Gutkin

Dynamics and function of neuronal networks are determined by their synaptic connectivity. Current experimental methods to analyze synaptic network structure on the cellular level, however, cover only small fractions of functional neuronal…

Neurons and Cognition · Quantitative Biology 2015-07-28 Yury V. Zaytsev , Abigail Morrison , Moritz Deger

Rhythmic activities that alternate between coherent and incoherent phases are ubiquitous in chemical, ecological, climate, or neural systems. Despite their importance, general mechanisms for their emergence are little understood. In order…

Adaptation and Self-Organizing Systems · Physics 2022-06-01 Max Thiele , Rico Berner , Peter A. Tass , Eckehard Schöll , Serhiy Yanchuk

Large networks of sparsely coupled, excitatory and inhibitory cells occur throughout the brain. A striking feature of these networks is that they are chaotic. How does this chaos manifest in the neural code? Specifically, how variable are…

Neurons and Cognition · Quantitative Biology 2014-02-25 Guillaume Lajoie , Jean-Philippe Thivierge , Eric Shea-Brown