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Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

We formulate a general, high-dimensional kinetic theory describing the internal state (such as gene expression or protein levels) of cells in a stochastically evolving population. The resolution of our kinetic theory also allows one to…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Tom Chou

The recent interest in human dynamics has led researchers to investigate the stochastic processes that explain human behaviour in different contexts. Here we propose a generative model to capture the essential dynamics of survival analysis,…

Physics and Society · Physics 2015-06-18 Trevor Fenner , Mark Levene , George Loizou

In this paper, we consider a stochastic ratio-dependent predator-prey model. We firstly prove the existence, uniqueness and positivity of the solutions. Then, the boundedness of moments of population are studied. Finally, we show the…

Probability · Mathematics 2015-09-01 Nguyen Thi Hoai Linh , Ta Viet Ton

We investigate the evolutionary dynamics of a population structured in phenotype, subjected to trait dependent selection with a linearly moving optimum and an asexual mode of reproduction. Our model consists of a non-local and non-linear…

Analysis of PDEs · Mathematics 2021-12-09 Raphaël Forien , Jimmy Garnier , Florian Patout

We study the evolutionary dynamics of a phenotypically structured population in a changing environment , where the environmental conditions vary with a linear trend but in an oscillatory manner. Such phenomena can be described by parabolic…

Analysis of PDEs · Mathematics 2021-05-04 Susely Figueroa Iglesias , Sepideh Mirrahimi

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

Recently, a first step was made by the authors towards a systematic investigation of the effect of reaction-step-size noise - uncertainty in the step size of the reaction - on the dynamics of stochastic populations. This was done by…

Statistical Mechanics · Physics 2016-12-21 Shay Be'er , Michael Assaf

We develop a stochastic two-patch epidemic model with nonlinear recidivism to investigate infectious disease dynamics in heterogeneous populations. Extending a deterministic framework, we introduce stochasticity to account for random…

Populations and Evolution · Quantitative Biology 2024-05-21 Juan G. Calvo , Mario I. Simoy , Juan P. Aparicio , José E. Chacón , Fabio Sanchez

We exhibit a stochastic discrete time model that has exactly the Eigen model as its deterministic continuous limit. Such model can be divided into two phases: reproduction followed by neutral selection. This result suggests that Eigen model…

Populations and Evolution · Quantitative Biology 2011-02-03 Fabio Musso

An individual-based model of stochastic branching is proposed and studied, in which point particles drift in $\bar{\mathds{R}}_{+}:=[0,+\infty)$ towards the origin (edge) with unit speed, where each of them splits into two particles that…

Dynamical Systems · Mathematics 2019-10-30 Yuri Kozitsky

Identifying the critical domain size necessary for a population to persist is an important question in ecology. Both demographic and environmental stochasticity impact a population's ability to persist. Here we explore ways of including…

Populations and Evolution · Quantitative Biology 2016-01-22 Jody R. Reimer , Michael B. Bonsall , Philip K. Maini

There have been many studies to examine whether one trait is correlated with another trait across a group of present-day species (for example, do species with larger brains tend to have longer gestation times. Since the introduction of the…

Populations and Evolution · Quantitative Biology 2023-09-07 Albert Ch. Soewongsono , Barbara R. Holland , Malgorzata M. O'Reilly

Spatially extended population dynamics models that incorporate intrinsic noise serve as case studies for the role of fluctuations and correlations in biological systems. Including spatial structure and stochastic noise in predator-prey…

Statistical Mechanics · Physics 2018-01-09 Ulrich Dobramysl , Mauro Mobilia , Michel Pleimling , Uwe C. Täuber

We study the population profile in a simple discrete time model of population dynamics. Our model, which is closely related to certain ``bit-string'' models of evolution, incorporates competition for resources via a population dependent…

Statistical Mechanics · Physics 2009-10-31 Martin Howard , R. K. P. Zia

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

Tissues and Organs · Quantitative Biology 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

Discrete time, spatially extended models play an important role in ecology, modelling population dynamics of species ranging from micro-organisms to birds. An important question is how 'bottom up', individual-based models can be…

Populations and Evolution · Quantitative Biology 2023-01-20 Linnéa Gyllingberg , David J. T. Sumpter , Åke Brännström

Spatial metapopulation models are fundamental to theoretical ecology, enabling to study how landscape structure influences global species dynamics. Traditional models, including recent generalizations, often rely on the deterministic limit…

Populations and Evolution · Quantitative Biology 2025-06-24 Alice Doimo , Giorgio Nicoletti , Davide Bernardi , Prajwal Padmanabha

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

Molecular Networks · Quantitative Biology 2015-04-28 Thierry Mora , Aleksandra M. Walczak

Community assembly is studied using individual-based multispecies models. The models have stochastic population dynamics with mutation, migration, and extinction of species. Mutants appear as a result of mutation of the resident species,…

Populations and Evolution · Quantitative Biology 2010-05-18 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold