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The robustness of an ecological network quantifies the resilience of the ecosystem it represents to species loss. It corresponds to the proportion of species that are disconnected from the rest of the network when extinctions occur…

Populations and Evolution · Quantitative Biology 2021-11-25 Saint-Clair Chabert-Liddell , Pierre Barbillon , Sophie Donnet

Residual networks (ResNets) have displayed impressive results in pattern recognition and, recently, have garnered considerable theoretical interest due to a perceived link with neural ordinary differential equations (neural ODEs). This link…

Machine Learning · Computer Science 2021-06-11 Alain-Sam Cohen , Rama Cont , Alain Rossier , Renyuan Xu

Random fiber networks form the structural foundation of numerous biological tissues and engineered materials. From a mechanics perspective, understanding the structure-function relationships of random fiber networks is particularly…

Soft Condensed Matter · Physics 2025-06-24 Peerasait Prachaseree , Emma Lejeune

We review the recent fast progress in statistical physics of evolving networks. Interest has focused mainly on the structural properties of random complex networks in communications, biology, social sciences and economics. A number of giant…

Statistical Mechanics · Physics 2015-06-24 S. N. Dorogovtsev , J. F. F. Mendes

Reaction networks are systems in which the populations of a finite number of species evolve through predefined interactions. Such networks are found as modeling tools in many biological disciplines such as biochemistry, ecology,…

Molecular Networks · Quantitative Biology 2015-06-15 Ankit Gupta , Corentin Briat , Mustafa Khammash

Random networks are increasingly used to analyse complex transportation networks, such as airline routes, roads and rail networks. So far, this research has been focused on describing the properties of the networks with the help of random…

Physics and Society · Physics 2017-09-19 Jürgen Hackl , Bryan T. Adey

How do networks of relationships evolve over time? We analyse a dataset tracking the social interactions of 900 individuals over four years. Despite continuous shifts in individual relationships, the macroscopic structural properties of the…

Physics and Society · Physics 2025-06-04 Miguel A. González-Casado , Andreia Sofia Teixeira , Angel Sánchez

We present a sequence-based probabilistic formalism that directly addresses co-operative effects in networks of interacting positions in proteins, providing significantly improved contact prediction, as well as accurate quantitative…

Quantitative Methods · Quantitative Biology 2012-07-12 Alan Lapedes , Bertrand Giraud , Christopher Jarzynski

Analyzing nonlinear conformational relaxation dynamics in elastic networks corresponding to two classical motor proteins, we find that they respond by well-defined internal mechanical motions to various initial deformations and that these…

Biomolecules · Quantitative Biology 2007-06-13 Yuichi Togashi , Alexander S. Mikhailov

The relationship between network topology and system dynamics has significant implications for unifying our understanding of the interplay among metabolic, gene-regulatory, and ecosystem network architecures. Here we analyze the stability…

Populations and Evolution · Quantitative Biology 2015-06-17 Cameron Smith , Raymond S. Puzio , Aviv Bergman

Residual networks (Resnets) have become a prominent architecture in deep learning. However, a comprehensive understanding of Resnets is still a topic of ongoing research. A recent view argues that Resnets perform iterative refinement of…

Computer Vision and Pattern Recognition · Computer Science 2018-03-09 Stanisław Jastrzębski , Devansh Arpit , Nicolas Ballas , Vikas Verma , Tong Che , Yoshua Bengio

Allosteric effects are often underlying the activity of proteins and elucidating generic design aspects and functional principles which are unique to allosteric phenomena represents a major challenge. Here an approach which consists in the…

Biological Physics · Physics 2017-02-28 Holger Flechsig

We investigate the topics of sensitivity and robustness in feedforward and convolutional neural networks. Combining energy landscape techniques developed in computational chemistry with tools drawn from formal methods, we produce empirical…

Machine Learning · Statistics 2018-12-06 Timothy E. Wang , Yiming Gu , Dhagash Mehta , Xiaojun Zhao , Edgar A. Bernal

A protein structure is represented as a network of residues whereby edges are determined by intra-molecular contacts. We introduce inhomogeneity into these networks by assigning each edge a weight that is determined by amino-acid pair…

Soft Condensed Matter · Physics 2007-06-13 Ali Rana Atilgan , Deniz Turgut , Canan Atilgan

Self-avoiding random walks were performed on protein residue networks. Compared with protein residue networks with randomized links, the probability of a walk being successful is lower and the length of successful walks shorter in…

Molecular Networks · Quantitative Biology 2013-06-11 Susan Khor

All types of networks arise as intricate combinations of dyadic building blocks formed by pairs of vertices. In directed networks, the dyadic patterns are entirely determined by reciprocity, i.e. the tendency to form, or to avoid, mutual…

Data Analysis, Statistics and Probability · Physics 2014-01-14 Tiziano Squartini , Francesco Picciolo , Franco Ruzzenenti , Diego Garlaschelli

Networks of elastic beams can deform either by stretching or bending of their members. The primary mode of deformation (bending or stretching) crucially depends on the specific details of the network architecture. In order to shed light on…

Soft Condensed Matter · Physics 2016-09-23 Gérald Gurtner , Marc Durand

Empirical data on real complex systems are becoming increasingly available. Parallel to this is the need for new methods of reconstructing (inferring) the topology of networks from time-resolved observations of their node-dynamics. The…

Dynamical Systems · Mathematics 2019-09-16 Marc G. Leguia , Zoran Levnajic , Ljupco Todorovski , Bernard Zenko

Adaptive transport networks in biological and physical systems exhibit hierarchical organization, characteristic channel spacing, and robust scaling relations. Existing adaptive network models, formulated on a lattice, successfully…

Adaptation and Self-Organizing Systems · Physics 2026-05-18 Sidney Holden , Mia C. Morrell , Geoffrey Vasil , Eleni Katifori

Deep neural networks such as AlphaFold and RoseTTAFold predict remarkably accurate structures of proteins compared to other algorithmic approaches. It is known that biologically small perturbations in the protein sequence do not lead to…

Biomolecules · Quantitative Biology 2021-09-21 Sumit Kumar Jha , Arvind Ramanathan , Rickard Ewetz , Alvaro Velasquez , Susmit Jha