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We study the 2D motion of colloidal dimers by single-particle tracking and compare the experimental observations obtained by bright-field microscopy to theoretical predictions for anisotropic diffusion. The comparison is based on the…

Lipid monolayers with phase coexistence are a frequently used model for lipid membranes. In these systems, domains of the liquid-condensed phase always present size polydispersity. However, very few theoretical works consider size…

Biological Physics · Physics 2023-05-18 Elena Rufeil Fiori , Adolfo J. Banchio

Most classical work on the hydrodynamics of low-Reynolds-number swimming addresses deterministic locomotion in quiescent environments. Thermal fluctuations in fluids are known to lead to a Brownian loss of the swimming direction. As most…

Fluid Dynamics · Physics 2014-06-18 Mario Sandoval , Navaneeth K. M. , Ganesh Subramanian , Eric Lauga

We calculate the diffusion coefficients of persistent random walks on cubic and hypercubic lattices, where the direction of a walker at a given step depends on the memory of one or two previous steps. These results are then applied to study…

Statistical Mechanics · Physics 2013-02-07 Thomas Gilbert , Huu Chuong Nguyen , David P Sanders

We consider a drift-diffusion model, with an unknown function depending on the spatial variable and an additional structural variable, the amount of ingested lipid. The diffusion coefficient depends on this additional variable. The drift…

Analysis of PDEs · Mathematics 2023-05-10 Cosmin Burtea , Nicolas Meunier , Clément Mouhot

Field-theoretical method is proposed, that yields analytical expression for lateral pressure distribution across hydrophobic core of a bilayer lipid membrane. Lipid molecule, repelling entropicaly surrounding neighbors, is modeled as a…

Soft Condensed Matter · Physics 2007-05-23 Sergei I. Mukhin , Svetlana V. Baoukina

Cholesterol (CHOL) is one of the most important components of plasma membranes of higher cells and one of the main factors for the formation of (nano)domains. In this work, molecular dynamics simulations of mixtures of CHOL with DPPC…

Biological Physics · Physics 2022-08-11 Fabian Keller , Andreas Heuer

Doxorubicin (DOX) is one of the most efficient antitumor drugs employed in numerous cancer therapies. Its incorporation into lipid-based nanocarriers, such as liposomes, improves the drug targeting into tumor cells and reduces drug side…

Soft Condensed Matter · Physics 2021-09-07 Paulo Siani , Edoardo Donadoni , Lorenzo Ferraro , Francesca Re , Cristiana Di Valentin

We consider the diffusion of markers in a layered medium, with the lateral diffusion coefficient being the function of hight. We show that the probability density of the lateral displacements follows one-dimensional Batchelor's equation…

Mesoscale and Nanoscale Physics · Physics 2014-04-28 Eugene B. Postnikov , Igor M. Sokolov

The assembly of proteins in membranes plays a key role in many crucial cellular pathways. Despite their importance, characterizing transmembrane assembly remains challenging for experiments and simulations. Equilibrium molecular dynamics…

Soft Condensed Matter · Physics 2024-08-05 Emil Jackel , Gianmarco Lazzeri , Roberto Covino

We study the stress distribution profiles and the height and thickness fluctuations of lipid membranes in the tilted gel state by Monte Carlo simulations of a generic coarse-grained model for lipid membranes, which reproduces many known…

Soft Condensed Matter · Physics 2010-02-24 Beate West , Friederike Schmid

We have studied the collective short wavelength dynamics in deuterated DMPC bilayers by inelastic neutron scattering. The corresponding dispersion relation $\hbar\omega$(Q) is presented for the gel and fluid phase of this model system. The…

Soft Condensed Matter · Physics 2007-05-23 M. C. Rheinstädter , C. Ollinger , F. Demmel , G. Fragneto , T. Salditt

We study agitated frictional disks in two dimensions with the aim of developing a scaling theory for their diffusion over time. As a function of the area fraction $\phi$ and mean-square velocity fluctuations $\langle v^2\rangle$ the…

Soft Condensed Matter · Physics 2019-10-09 H. G. E. Hentschel , Itamar Procaccia , Saikat Roy

A minimalist simulation model for lipid bilayers is presented. Each lipid is represented by a flexible chain of beads in implicit solvent. The hydrophobic effect is mimicked through an intermolecular pair potential localized at the…

Statistical Mechanics · Physics 2009-11-11 Grace Brannigan , Peter F. Philips , Frank L. H. Brown

We extend the phase field crystal model to accommodate exact atomic configurations and vacancies by requiring the order parameter to be non-negative. The resulting theory dictates the number of atoms and describes the motion of each of…

Computational Physics · Physics 2009-02-10 Pak Yuen Chan , Nigel Goldenfeld , Jon Dantzig

We report on the short-time dynamics in colloidal mixtures made up of monomers and dimers highly confined between two glass-plates. At low concentrations, the experimental measurements of colloidal motion agree well with the solution of the…

We study the dynamic structure of lipid domain inclusions embedded within a phase-separated reconstituted lipid bilayer in contact with a swarming flow of gliding filamentous actin. Passive circular domains transition into highly-deformed…

Soft Condensed Matter · Physics 2024-06-12 Aakanksha Gubbala , Daniel P. Arnold , Anika Jena , Stephanie Anujarerat , Sho C. Takatori

We investigate pores in fluid membranes by molecular dynamics simulations of an amphiphile-solvent mixture, using a molecular coarse-grained model. The amphiphilic membranes self-assemble into a lamellar stack of amphiphilic bilayers…

Soft Condensed Matter · Physics 2009-11-11 Claire Loison , Michel Mareschal , Friederike Schmid

We present a minimal model for simulating dynamics of assorted lipid assemblies in a computationally efficient manner. Our model is particle-based and consists of coarse-grained beads put together on a modular platform to give generic…

Chemical Physics · Physics 2019-10-15 John M. A. Grime , Jesper J. Madsen

We present a simple, and physically motivated, coarse-grained model of a lipid bilayer, suited for micron scale computer simulations. Each ~25 nm^2 patch of bilayer is represented by a spherical particle. Mimicking forces of hydrophobic…

Soft Condensed Matter · Physics 2015-05-13 Andrea Pasqua , Lutz Maibaum , George Oster , Daniel A. Fletcher , Phillip L. Geissler
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