Related papers: Contagious obesity: from adenovirus 36 to RB dysfu…
Prediabetes is a common health condition that often goes undetected until it progresses to type 2 diabetes. Early identification of prediabetes is essential for timely intervention and prevention of complications. This research explores the…
Diabetes is considered as an critical comorbidity linked with the latest coronavirus disease 2019 (COVID-19) which spreads through Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2). The diabetic patients have higher threat of…
Survival of living tumor cells underlies many influences such as nutrient saturation, oxygen level, drug concentrations or mechanical forces. Data-supported mathematical modeling can be a powerful tool to get a better understanding of cell…
The ribosome is responsible for protein synthesis in all cells, and is the largest energy consumer in the cell. We propose that the ribosome originated as a mutualistic symbiont of an RNA-dependent RNA polymerase ribozyme, supplying…
Massive stars exhibit a variety of instabilities, many of which are poorly understood. We explore instabilities induced by centrifugal forces and angular momentum transport in massive rotating stars. First, we derive and numerically solve…
SARS-CoV-2 coronavirus infection is mediated by the binding of its spike protein to the angiotensin-converting enzyme 2 (ACE2), which plays a pivotal role in the renin-angiotensin system (RAS). The study of RAS dysregulation due to…
Resection of primary tumors is often followed by accelerated growth of metastases. Here we propose that this effect may be due to the fact that resection of primary tumor results in a decrease in the total systemic amount of angiogenesis…
Aging is a multifactorial process and a key factor of morbidity and mortality. Alzheimer's disease (AD) is an age-related disorder and a main cause of worldwide disability. Both aging and AD can be characterized by metabolic dysfunction.…
Obstructive sleep apnea (OSA) is a sleep respiratory disease characterized by sleep snoring accompanied by apnea and daytime sleeplessness. It is a complex disease, with the multifactorial etiology, and the pathology is incompletely…
We describe the general setting for the optical Aharonov-Bohm effect based on the inverse problem of the identification of the coefficients of the governing hyperbolic equation by the boundary measurements. We interpret the inverse problem…
Translation of proteins is a fundamental part of gene expression that is mediated by ribosomes. As ribosomes significantly contribute to both cellular mass and energy consumption, achieving efficient management of the ribosome population is…
Polycystic Ovary Syndrome (PCOS) is an endrocrinological dysfunction prevalent among women of reproductive age. PCOS is a combination of syndromes caused by an excess of androgens - a group of sex hormones - in women. Syndromes including…
An optimal control problem for a model of tumor growth is studied. In a given subdomain, it is required to minimize the density of tumor cells, while the drug concentration in tissue is limited by given minimal and maximal values. Based on…
The possibility of targeting the causal genes along with the mechanisms of pathogenically complex diseases has led to numerous studies on the genetic etiology of some diseases. In particular, studies have added more genes to the list of…
Diabetic Retinopathy (DR) has emerged as a major cause of preventable blindness in recent times. With timely screening and intervention, the condition can be prevented from causing irreversible damage. The work introduces a state-of-the-art…
Obesity is one of the major health risk factors be- hind the rise of non-communicable conditions. Understanding the factors influencing obesity is very complex since there are many variables that can affect the health behaviors leading to…
Although previous observational studies have shown associations between serum 25-hydroxyvitamin D (25(OH)D) concentration and metabolic syndrome, this association has not yet been investigated among Aboriginal and Torres Strait Islander…
Age dependent performance disparities in medical image classification often arise because age acts as a confounder, linking imaging morphology with disease prevalence. In practice, disparities can manifest as overdiagnosis at ages where…
The planetary restricted three-body problem (RTBP) is considered. The primary mass M is much more than another masses mj, i=1..N, which revolve around M. The massless probe particle m moves on elliptic orbit, is perturbed by mj. It is well…
To use social media for health-related analysis, one key step is the detection of health-related labels for users. But unlike transient conditions like flu, social media users are less vocal about chronic conditions such as obesity, as…