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Bacterial cells exhibit a diverse array of shapes and sizes, largely governed by their cell walls in conjunction with cytoskeletal proteins and internal turgor pressure. The present study develops a theoretical framework for modeling the…

Biological Physics · Physics 2024-09-25 Joydip Chaudhuri

Biomolecular condensates are small droplets forming spontaneously in biological cells via phase separation. They play a role in many cellular processes, but it is unclear how cells control them. Cellular regulation often relies on…

Soft Condensed Matter · Physics 2024-03-15 Jan Kirschbaum , David Zwicker

We introduce a theoretical approach to study the quantum-dissipative dynamics of electronic excitations in macromolecules, which enables to perform calculations in large systems and cover long time intervals. All the parameters of the…

Mesoscale and Nanoscale Physics · Physics 2016-07-20 S. A Beccara , F. Mascherpa , E. Schneider , P. Faccioli

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

Cell Behavior · Quantitative Biology 2015-12-09 Gabriele Micali , Robert G. Endres

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

Probability · Mathematics 2022-04-27 Nam H Nguyen , Marek Kimmel

A macroscopic theory for describing cellular states during steady-growth is presented, which is based on the consistency between cellular growth and molecular replication, as well as the robustness of phenotypes against perturbations.…

Populations and Evolution · Quantitative Biology 2021-02-08 Kunihiko Kaneko , Chikara Furusawa

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

Cell Behavior · Quantitative Biology 2018-08-16 Enrico Gavagnin , Christian A. Yates

Droplets are essential for spatially controlling biomolecules in cells. To work properly, cells need to control the emergence and morphology of droplets. On the one hand, driven chemical reactions can affect droplets profoundly. For…

Soft Condensed Matter · Physics 2024-03-14 Noah Ziethen , David Zwicker

Activity-mediated unjamming of a confluent glassy system is crucial for several biological processes, such as embryogenesis and cancer metastasis. During these processes, the cells progressively change their junction properties,…

Soft Condensed Matter · Physics 2025-05-13 Souvik Sadhukhan , Chandan Dasgupta , Saroj Kumar Nandi

Large-scale molecular dynamics simulations are used to simulate a layer of nanoparticles diffusing on the surface of a liquid. Both a low viscosity liquid, represented by Lennard-Jones monomers, and a high viscosity liquid, represented by…

Soft Condensed Matter · Physics 2013-01-10 Shengfeng Cheng , Gary S. Grest

Stochastic dynamical systems arise naturally across nearly all areas of science and engineering. Typically, a dynamical system model is based on some prior knowledge about the underlying dynamics of interest in which probabilistic features…

Computational Engineering, Finance, and Science · Computer Science 2021-09-03 Chao Yin , Xihaier Luo , Ahsan Kareem

In this paper, we propose a numerical investigation of topological interactions in flocking dynamics. Starting from a microscopic description of the phenomena, mesoscopic and macroscopic models have been previously derived under specific…

Analysis of PDEs · Mathematics 2025-12-30 Marta Menci , Thierry Paul , Stefano Rossi , Tommaso Tenna

Traditional chemical kinetics may be inappropriate to describe chemical reactions in micro-domains involving only a small number of substrate and reactant molecules. Starting with the stochastic dynamics of the molecules, we derive a…

Mathematical Physics · Physics 2009-11-10 D. Holcman , Z. Schuss

We report Monte Carlo simulations of the dynamics of a "chucker": a colloidal particle which emits smaller solute particles from its surface, isotropically and at a constant rate k_c. We find that the diffusion constant of the chucker…

Soft Condensed Matter · Physics 2015-05-14 C. Valeriani , R. J. Allen , D. Marenduzzo

In this paper, we study the stationary states of diffusive dynamics driven out of equilibrium by reservoirs. For a small forcing, the system remains close to equilibrium and the large deviation functional of the density can be computed…

Statistical Mechanics · Physics 2024-12-19 Thierry Bodineau , Bernard Derrida

In this work, we study a model of the chemostat where the species are present in two forms, isolated bacteria and under an aggregated form like attached bacteria or bacteria in flocks. We show that our general model contains a lot of models…

Dynamical Systems · Mathematics 2012-03-13 Radhoaune Fekih-Salem , Jérôme Harmand , Claude Lobry , Alain Rapaport , Tewfik Sari

Understanding the physics of non-equilibrium systems remains as one of the major open questions in statistical physics. This problem can be partially handled by investigating macroscopic fluctuations of key magnitudes that characterise the…

Soft Condensed Matter · Physics 2016-11-17 A. Lasanta , Pablo I. Hurtado , A. Prados

Mathematical models have been widely used to describe the collective movement of bacteria by chemotaxis. In particular, bacterial concentration waves traveling in a narrow channel have been experimentally observed and can be precisely…

Analysis of PDEs · Mathematics 2016-04-15 Casimir Emako , Charlène Gayrard , Axel Buguin , Luís Neves de Almeida , Nicolas Vauchelet

We propose a mathematical kinetic framework to investigate interactions between tumor cells and the immune system, focusing on the spatial dynamics of tumor progression and immune responses. We develop two kinetic models: one describes a…

Cell Behavior · Quantitative Biology 2026-02-24 Martina Conte , Romina Travaglini

The effective, fast transport of matter through porous media is often characterized by complex dispersion effects. To describe in mathematical terms such situations, instead of a simple macroscopic equation (as in the classical Darcy's…

Numerical Analysis · Mathematics 2025-05-06 Surendra Nepal , Vishnu Raveendran , Michael Eden , Rainey Lyons , Adrian Muntean
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