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A univariate Hawkes process is a simple point process that is self-exciting and has clustering effect. The intensity of this point process is given by the sum of a baseline intensity and another term that depends on the entire past history…

Probability · Mathematics 2018-10-04 Xuefeng Gao , Lingjiong Zhu

Analysis of the cell population generally provides average information about viral infection in a host whereas the intracellular model captures the individual cellular responses. The primary goal of this study is to comprehensively analyze…

Dynamical Systems · Mathematics 2025-05-20 Rupchand Sutradhar , D C Dalal

We review some recent results of quantitative long-time convergence for the law of a killed Markov process conditioned to survival toward a quasi-stationary distribution, and on the analogous question for the particle systems used in…

Probability · Mathematics 2023-05-26 Bertrand Cloez , Lucas Journel , Pierre Monmarché , Boris Nectoux , Mouad Ramil

Existing methods to estimate the prevalence of chronic hepatitis C (HCV) in New York City (NYC) are limited in scope and fail to assess hard-to-reach subpopulations with highest risk such as injecting drug users (IDUs). To address these…

Applications · Statistics 2018-01-16 Sarah Tan , Susanna Makela , Daliah Heller , Kevin Konty , Sharon Balter , Tian Zheng , James H. Stark

Many countries have experienced at least two waves of the COVID-19 pandemic. The second wave is far more dangerous as distinct strains appear more harmful to human health, but it stems from the complacency about the first wave. This paper…

Populations and Evolution · Quantitative Biology 2022-06-29 Edilson F. Arruda , Tarun Sharma , Rodrigo e A. Alexandre , Sinnu Susan Thomas

We consider a nonequilibrium reaction-diffusion model on a finite one dimensional lattice with bulk and boundary dynamics inspired by Glauber dynamics of the Ising model. We show that the model has a rich algebraic structure that we use to…

Statistical Mechanics · Physics 2011-04-20 Arvind Ayyer , Kirone Mallick

In this paper we consider large state space continuous time Markov chains (MCs) arising in the field of systems biology. For density dependent families of MCs that represent the interaction of large groups of identical objects, Kurtz has…

Performance · Computer Science 2015-03-04 Alessio Angius , Gianfranco Balbo , Marco Beccuti , Enrico Bibbona , Andras Horvath , Roberta Sirovich

Competing risks model time to first event and type of first event. An example from hospital epidemiology is the incidence of hospital-acquired infection, which has to account for hospital discharge of non-infected patients as a competing…

Methodology · Statistics 2013-04-09 Arthur Allignol , Jan Beyersmann , Thomas Gerds , Aurélien Latouche

Extending deterministic compartments pharmacokinetic models as diffusions seems not realistic on biological side because paths of these stochastic processes are not smooth enough. In order to extend one compartment intra-veinous bolus…

Probability · Mathematics 2019-01-16 Nicolas Marie

The impact of spatial structure on the spread of an epidemic is an important issue in the propagation of infectious diseases. Recent studies, both deterministic and stochastic, have made it possible to understand the importance of the…

Probability · Mathematics 2023-01-09 Alphonse Emakoua

In this survey paper, we review the recent advances in individual based non--Markovian epidemic models. They include epidemic models with a constant infectivity rate, varying infectivity rate or infection-age dependent infectivity,…

Probability · Mathematics 2022-09-26 Raphael Forien , Guodong Pang , Etienne Pardoux

Two simple agent based models are often employed in epidemic studies: the susceptible-infected (SI) and the susceptible-infected-susceptible (SIS). Both models describe the time evolution of infectious diseases in networks in which vertices…

In this paper, a mathematical analysis of the global dynamics of a viral infection model in vivo is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both extracellular and intracellular…

Populations and Evolution · Quantitative Biology 2020-11-13 Alexis Nangue , Alan D. Rendall , Brice Kammegne Tcheugam , Patrick Steve Kamdem Simo

The main aim to build models capable of simulating the spreading of infectious diseases is to control them. And along this way, the key to find the optimal strategy for disease control is to obtain a large number of simulations of disease…

Social and Information Networks · Computer Science 2022-04-22 Ting Wang , Gui-Yun Li , Xin-Hui Li , Chi-Chun Zhou , Yuan-Yuan Wang , Li-Juan Li , Yan-Ting Yang

We propose a novel, tractable latent state inference scheme for Markov jump processes, for which exact inference is often intractable. Our approach is based on an entropic matching framework that can be embedded into the well-known…

Machine Learning · Computer Science 2026-02-27 Yannick Eich , Bastian Alt , Heinz Koeppl

Infection spread among individuals is modelled with a continuous time Markov chain, in which subject interactions depend on their distance in space. The well known SIR model and non local variants of the latter are then obtained as large…

Probability · Mathematics 2023-09-27 Franco Flandoli , Francesco Grotto , Andrea Papini , Cristiano Ricci

Pathology tests are central to modern healthcare in terms of diagnosis and patient management. Aggregated pathology results provide opportunities for research into fundamental and applied questions in health and medicine, but data analytic…

Applications · Statistics 2022-05-05 N. Menon , B. A. Lidbury , A. M. Richardson

We propose to use quantum computers to simulate infection spreading in networks. We first show the analogy between the infection distribution and spin-lattice configurations with Ising-type interactions. Then, since the spreading process…

Quantum Physics · Physics 2023-06-16 Xiaoyang Wang , Yinchenguang Lyu , Changyu Yao , Xiao Yuan

This paper demonstrates a lower and upper solution method to investigate the asymptotic behaviour of the conservative reaction-diffusion systems associated with Markovian process algebra models. In particular, we have proved the uniform…

Performance · Computer Science 2022-11-18 Jie Ding , Ruiming Ma , Zhigui Lin , Zhi Ling

We establish central limit theorems for a large class of supercritical branching Markov processes in infinite dimension with spatially dependent and non-necessarily local branching mechanisms. This result relies on a fourth moment…

Probability · Mathematics 2025-01-31 Bertrand Cloez , Nicolás Zalduendo