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Hypoelliptic diffusion processes can be used to model a variety of phenomena in applications ranging from molecular dynamics to audio signal analysis. We study parameter estimation for such processes in situations where we observe some…

Methodology · Statistics 2007-10-30 Y. Pokern , A. M. Stuart , P. Wiberg

Local drug delivery has received much recognition in recent years, yet it is still unpredictable how drug efficacy depends on physicochemical properties and delivery kinetics. The purpose of the current study is to provide a useful…

Dynamical Systems · Mathematics 2016-01-26 Koyel Chakravarty , D C Dalal

Using a continuum bead-spring Monte Carlo model, we study the anomalous diffusion dynamics of a self-avoiding tethered membrane by means of extensive computer simulations. We focus on the subdiffusive stochastic motion of the membrane's…

Soft Condensed Matter · Physics 2008-05-14 Hristina Popova , Andrey Milchev

The physical approach of a small particle (virus, medical drug) to the cell membrane represents the crucial first step before active internalization and is governed by thermal diffusion. Using a fully analytical theory we show that the…

Fluid Dynamics · Physics 2016-02-17 Abdallah Daddi-Moussa-Ider , Achim Guckenberger , Stephan Gekle

We use the hyperbolic subdiffusion equation with fractional time derivatives (the generalized Cattaneo equation) to study the transport process of electrolytes in media where subdiffusion occurs. In this model the flux is delayed in a…

Statistical Mechanics · Physics 2009-11-13 Tadeusz Kosztolowicz , Katarzyna D. Lewandowska

We construct a nearest-neighbour interacting particle system of exclusion type, which illustrates a transition from slow to fast diffusion. More precisely, the hydrodynamic limit of this microscopic system in the diffusive space-time…

Probability · Mathematics 2023-01-18 Patricia Gonçalves , Gabriel Nahum , Marielle Simon

This paper considers membranes of globular structure in the framework of the cell model technique. Coupled micropolar and Brinkman-type equations are used to model the flow of micropolar fluid through a spherical cell, consisting of solid…

Fluid Dynamics · Physics 2020-05-05 D. Yu. Khanukaeva

We investigate experimentally the diffusion properties of a bidimensional bidisperse dry granular material under quasistatic cyclic shear.The comparison of these properties with results obtained both in computer simulations of hard spheres…

Disordered Systems and Neural Networks · Physics 2009-11-10 G. Marty , O. Dauchot

We study the transport properties of a system of active particles moving at constant speed in an heterogeneous two-dimensional space. The spatial heterogeneity is modeled by a random distribution of obstacles, which the active particles…

Biological Physics · Physics 2013-10-23 Oleksandr Chepizhko , Fernando Peruani

One of the promising frontiers of bioengineering is the controlled release of a therapeuticdrug from a vehicle across the skin (transdermal drug delivery). In order to study the complete process, a two-phase mathematical model describing…

Quantitative Methods · Quantitative Biology 2016-01-15 Giuseppe Pontrelli , Filippo de Monte

We consider the diffusion of markers in a layered medium, with the lateral diffusion coefficient being the function of hight. We show that the probability density of the lateral displacements follows one-dimensional Batchelor's equation…

Mesoscale and Nanoscale Physics · Physics 2014-04-28 Eugene B. Postnikov , Igor M. Sokolov

Using molecular dynamics simulations, we study the slow dynamics of supercooled liquids confined in a random matrix of immobile obstacles. We study the dynamical crossover from glass-like to Lorentz-gas-like behavior in terms of the density…

Soft Condensed Matter · Physics 2011-05-30 Kang Kim , Kunimasa Miyazaki , Shinji Saito

We investigate the influence of a self-propelling, out-of-equilibrium active particle on generalized elastic systems, including flexible and semiflexible polymers, fluid membranes, and fluctuating interfaces, while accounting for…

Soft Condensed Matter · Physics 2024-01-25 Alessandro Taloni

We consider subdiffusion in a system which consists of two media separated by a thin membrane. The subdiffusion parameters may be different in each of the medium. Using the new method presented in this paper we derive the probabilities (the…

Statistical Mechanics · Physics 2016-11-30 Tadeusz Kosztołowicz

We investigate diffusion of a peptide drug through Graphene Oxide (GO) membranes that are modeled as a porous layered laminate constructed from aligned flakes of GO. Our experiments using a peptide drug show a tunable non-linear dependence…

Materials Science · Physics 2015-12-29 T. M. Puvirajesinghe , Z. L. Zhi , R. V. Craster , S. Guenneau

This paper investigates a diffusion process in a narrow tubular domain with reflecting boundary conditions, where the geometry serves as a singular perturbation of an underlying graph in $\mathbb{R}^2$ or $\mathbb{R}^3$. The construction…

Probability · Mathematics 2025-09-04 Wen-Tai Hsu

We show that the concentration profiles in the subdiffusive system with a membrane, which separates a homogeneous solution from a pure solvent at an initial moment, has a general scaling form in the long time limit $C\sim t^\lambda…

Other Condensed Matter · Physics 2007-05-23 Tadeusz Kosztołowicz

We study parametric inference for ergodic diffusion processes with a degenerate diffusion matrix. Existing research focuses on a particular class of hypo-elliptic SDEs, with components split into `rough'/`smooth' and noise from rough…

Statistics Theory · Mathematics 2024-05-29 Yuga Iguchi , Alexandros Beskos , Matthew Graham

Diffusion of a tagged particle near a constraining biological surface is examined numerically by modeling the surface-water interaction by an effective potential. The effective potential is assumed to be given by an asymmetric double well…

Soft Condensed Matter · Physics 2007-05-23 Arnab Mukherjee , Biman Bagchi

We estimate the distribution of random parameters in a distributed parameter model with unbounded input and output for the transdermal transport of ethanol in humans. The model takes the form of a diffusion equation with the input being the…

Optimization and Control · Mathematics 2018-08-14 Melike Sirlanci , Susan E. Luczak , Catharine E. Fairbairn , Dahyeon Kang , Ruoxi Pan , Xin Yu , I. G. Rosen