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A detailed stochastic model of single-gene auto-regulation is established and its solutions are explored when mRNA dynamics is fast compared with protein dynamics and in the opposite regime. The model includes all the sources of randomness…

Biological Physics · Physics 2015-06-03 Tomás Aquino , Elsa Abranches , Ana Nunes

Monitoring small groups of sheep in spontaneous evolution in the field, we decipher behavioural rules that sheep follow at the individual scale in order to sustain collective motion. Individuals alternate grazing mode at null speed and…

Pattern Formation and Solitons · Physics 2018-12-27 Manon Azaïs , Stéphane Blanco , Richard Bon , Richard Fournier , Marie-Hélène Pillot , Jacques Gautrais

We consider diffusion-controlled release of particles from $d$-dimensional radially-symmetric geometries. A quantity commonly used to characterise such diffusive processes is the proportion of particles remaining within the geometry over…

Biological Physics · Physics 2023-09-20 Luke P. Filippini , Matthew J. Simpson , Elliot J. Carr

The global existence of bounded weak solutions to a diffusion system modeling biofilm growth is proven. The equations consist of a reaction-diffusion equation for the substrate concentration and a fourth-order Cahn-Hilliard-type equation…

Analysis of PDEs · Mathematics 2023-07-20 Christoph Helmer , Ansgar Jüngel

In this article we introduce an original model in order to study the emergence of chaos in a reaction diffusion system in the presence of self- and cross-diffusion terms. A Fourier Spectral Method is derived to approximate equilibria and…

Dynamical Systems · Mathematics 2024-12-24 Benjamin Aymard

With the advantages of high modeling accuracy and large bandwidth, recurrent neural network (RNN) based inversion model control has been proposed for output tracking. However, some issues still need to be addressed when using the RNN-based…

Systems and Control · Electrical Eng. & Systems 2020-01-03 Shengwen Xie , Juan Ren

In this work we consider a general non-autonomous hybrid system based on the integrate-and-fire model, widely used as simplified version of neuronal models and other types of excitable systems. Our unique assumption is that the system is…

Dynamical Systems · Mathematics 2013-11-25 Albert Granados , Martin Krupa , Frédérique Clément

We study the collective behavior of binary mixture of self-propelled particles. Particles moves along their heading direction with {\it variable speed} and interact through short range alignment interaction. A variable speed parameter…

Soft Condensed Matter · Physics 2020-04-22 Jay Prakash Singh , Shradha Mishra

The estimation of static parameters in dynamical systems and control theory has been extensively studied, with significant progress made in estimating varying parameters in specific system types. Suppose, in the general case, we have data…

Optimization and Control · Mathematics 2025-07-10 Jamiree Harrison , Enoch Yeung

Molecular noise in gene regulatory networks has two intrinsic components, one part being due to fluctuations caused by the birth and death of protein or mRNA molecules which are often present in small numbers and the other part arising from…

Molecular Networks · Quantitative Biology 2015-11-17 Davit A. Potoyan , Peter G. Wolynes

Here we present a study of stochastic resonance in an extended FitzHugh-Nagumo system with a field dependent activator diffusion. We show that the system response (here measured through the output signal-to-noise ratio) is enhanced due to…

Soft Condensed Matter · Physics 2009-11-11 C. J. Tessone , H. S. Wio

The Gradient Vector Flow (GVF) is a vector diffusion approach based on Partial Differential Equations (PDEs). This method has been applied together with snake models for boundary extraction medical images segmentation. The key idea is to…

Computer Vision and Pattern Recognition · Computer Science 2007-05-23 Gilson A. Giraldi , Leandro S. Marturelli , Paulo S. Rodrigues

We study computational aspects of repulsive Gibbs point processes, which are probabilistic models of interacting particles in a finite-volume region of space. We introduce an approach for reducing a Gibbs point process to the hard-core…

Data Structures and Algorithms · Computer Science 2023-12-15 Tobias Friedrich , Andreas Göbel , Maximilian Katzmann , Martin Krejca , Marcus Pappik

We study the patterns generated in finite-time sweeps across symmetry-breaking bifurcations in individual-based models. Similar to the well-known Kibble-Zurek scenario of defect formation, large-scale patterns are generated when model…

Statistical Mechanics · Physics 2013-12-04 Peter Ashcroft , Tobias Galla

We present the results of a detailed set of one-zone models that account for the coupling between pulsation and convection following the original prescriptions of Stellingwerf (1986). Motivated by the arbitrary nature of the input…

Astrophysics · Physics 2009-11-10 A. Munteanu , G. Bono , J. Jose , E. Garcia-Berro , R. F. Stellingwerf

We study diffusion properties of an inertial Brownian motor moving on a ratchet substrate, i.e. a periodic structure with broken reflection symmetry. The motor is driven by an unbiased time-periodic symmetric force which takes the system…

Statistical Mechanics · Physics 2021-03-25 Jakub Spiechowicz , Marcin Kostur , Jerzy Łuczka

This work presents RNAdiffusion, a latent diffusion model for generating and optimizing discrete RNA sequences of variable lengths. RNA is a key intermediary between DNA and protein, exhibiting high sequence diversity and complex…

Machine Learning · Computer Science 2024-10-03 Kaixuan Huang , Yukang Yang , Kaidi Fu , Yanyi Chu , Le Cong , Mengdi Wang

A common model of stochastic auto-regulatory gene expression describes promoter switching via cooperative protein binding, effective protein production in the active state and dilution of proteins. Here we consider an extension of this…

Subcellular Processes · Quantitative Biology 2020-04-07 James Holehouse , Abhishek Gupta , Ramon Grima

The aim of this paper is to investigate the use of Pyragas control on the stability of stationary, localised coherent structures in a general class of two-component, singularly perturbed, reaction-diffusion systems. We use noninvasive…

Dynamical Systems · Mathematics 2023-08-07 Frits Veerman , Isabelle Schneider

Gaussian process regression (GPR) is a powerful machine learning method which has recently enjoyed wider use, in particular in physical sciences. In its original formulation, GPR uses a square matrix of covariances among training data and…

Numerical Analysis · Mathematics 2023-09-08 Sergei Manzhos , Manabu Ihara