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To survive starvation, Bacillus subtilis forms durable spores. After asymmetric cell division, the septum grows around the forespore in a process called engulfment, but the mechanism of force generation is unknown. Here, we derived a novel…

Subcellular Processes · Quantitative Biology 2017-10-16 Li-Wei Yap , Robert G. Endres

The skin microbiome plays an important role in the maintenance of a healthy skin. It is an ecosystem, composed of several species, competing for resources and interacting with the skin cells. Imbalance in the cutaneous microbiome, also…

Quantitative Methods · Quantitative Biology 2022-06-22 Eléa Thibault Greugny , Georgios N Stamatas , François Fages

Motile eukaryotic cells display distinct modes of migration that often occur within the same cell type. It remains unclear, however, whether transitions between the migratory modes require changes in external conditions, or whether the…

Pattern Formation and Solitons · Physics 2025-05-29 Jack M. Hughes , Cristina Martinez-Torres , Carsten Beta , Leah Edelstein-Keshet , Arik Yochelis

Motivated by various recent experimental findings, we propose a dynamical model of intermittently self-propelled particles: active particles that recurrently switch between two modes of motion, namely an active run-state and a turn state,…

Soft Condensed Matter · Physics 2025-10-30 Agniva Datta , Carsten Beta , Robert Großmann

A spacially extended model of the collective behavior of a large number of locally acting organisms is proposed in which organisms move probabilistically between local cells in space, but with weights dependent on local morphogenetic…

adap-org · Physics 2008-06-25 Mark M. Millonas

Periodic reversals of the direction of motion in systems of self-propelled rod shaped bacteria enable them to effectively resolve traffic jams formed during swarming and maximize their swarming rate. In this paper, a connection is found…

Biological Physics · Physics 2015-03-17 Richard Gejji , Pavel M. Lushnikov , Mark Alber

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

Biological Physics · Physics 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

The possibility of coexistence of two competing populations is a classical question which dates back to the earliest `predator-prey' models. In this paper we study this question in the context of a model for the spread of a virus infection…

Probability · Mathematics 2012-10-30 Jakob E. Björnberg , Erik I. Broman

Bacteria are known to exchange genetic information by horizontal gene transfer. Since the frequency of homologous recombination depends on the similarity of recombining segments, several studies examined whether this could lead to the…

Probability · Mathematics 2015-06-09 Sergey Pirogov , Aleksandre Rybko , Anastasia Kalinina , Mikhail Gelfand

While bacterial swarms can exhibit active turbulence in vacant spaces, they naturally inhabit crowded environments. We numerically show that driving disorderly active fluids through porous media enhances Darcy's law. While purely active…

Soft Condensed Matter · Physics 2024-03-19 Ryan R. Keogh , Timofey Kozhukhov , Kristian Thijssen , Tyler N. Shendruk

Microbial ecosystems are commonly modeled by fixed interactions between species in steady exponential growth states. However, microbes often modify their environments so strongly that they are forced out of the exponential state into…

Populations and Evolution · Quantitative Biology 2024-01-08 Avaneesh V. Narla , Terence Hwa , Arvind Murugan

The adaptation of biological species to their environment depends on their traits. When various biological processes occur (survival, reproduction, migration, etc.), the trait distribution may change with respect to time and space. In the…

Analysis of PDEs · Mathematics 2021-05-07 Léonard Dekens , Florian Lavigne

We study a reaction-diffusion model posed on two distinct spatial scales that accounts for diffusion, aggregation, fragmentation, and deposition of populations of colloidal particles within a porous material. In this model, the macroscopic…

Analysis of PDEs · Mathematics 2026-04-14 Christos Nikolopoulos , Michael Eden , Adrian Muntean

We introduce the liquid bin model as a continuous-time deterministic dynamics, arising as the hydrodynamic limit of a discrete-time stochastic interacting particle system called the infinite bin model. For the liquid bin model, we prove the…

Mathematical Physics · Physics 2025-04-02 Sanjay Ramassamy , Benjamin Terlat

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

Biological Physics · Physics 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

Colloids coupled to a bath of swimming cells generically display enhanced diffusion. This transport dynamics stems from a subtle interplay between the active and passive particles that still resists our understanding despite decades of…

Soft Condensed Matter · Physics 2021-03-25 Antoine Lagarde , Noémie Dagès , Takahiro Nemoto , Vincent Démery , Denis Bartolo , Thomas Gibaud

Natural selection favors the more successful individuals. This is the elementary premise that pervades common models of evolution. Under extreme conditions, however, the process may no longer be probabilistic. Those that meet certain…

Physics and Society · Physics 2014-03-07 Attila Szolnoki , Alberto Antonioni , Marco Tomassini , Matjaz Perc

Conjugation is the primary mechanism of horizontal gene transfer that spreads antibiotic resistance among bacteria. Although conjugation normally occurs in surface-associated growth (e.g., biofilms), it has been traditionally studied in…

Quantitative Methods · Quantitative Biology 2014-02-26 Peter D. Freese , Kirill S. Korolev , Jose I. Jimenez , Irene A. Chen

We consider a partial differential equation model for the growth of heterogeneous cell populations subdivided into multiple distinct discrete phenotypes. In this model, cells preferentially move towards regions where they feel less…

Analysis of PDEs · Mathematics 2025-04-04 José A. Carrillo , Tommaso Lorenzi , Fiona R. Macfarlane

For supercritical multitype branching processes in continuous time, we investigate the evolution of types along those lineages that survive up to some time t. We establish almost-sure convergence theorems for both time and population…

Probability · Mathematics 2007-05-23 Hans-Otto Georgii , Ellen Baake