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Chemical reactions can be understood as transformations of multigraphs (molecules) that preserve vertex labels (atoms) and degrees (sums of bonding and non-bonding electrons), thereby implying the atom-atom map of a reaction. The…

Combinatorics · Mathematics 2023-11-23 Christoph Flamm , Stefan Müller , Peter F. Stadler

This paper is concerned with the analysis of polyatomic gases within the framework of kinetic theory. Internal degrees of freedom are modeled using a single continuous variable corresponding to the molecular internal energy. Non-equilibrium…

Mathematical Physics · Physics 2016-11-15 Milana Pavić-Čolić , Damir Madjarević , Srboljub Simić

In a decision problem, observations are said to be material if they must be taken into account to perform optimally. Decision problems have an underlying (graphical) causal structure, which may sometimes be used to evaluate certain…

Other Statistics · Statistics 2024-07-16 Ryan Carey , Sanghack Lee , Robin J. Evans

Computational techniques are required for narrowing down the vast space of possibilities to plausible prebiotic scenarios, since precise information on the molecular composition, the dominant reaction chemistry, and the conditions for that…

Molecular Networks · Quantitative Biology 2018-02-07 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

We consider a system of reaction-diffusion equations including chemotaxis terms and coming out of the modeling of multiple sclerosis. The global existence of strong solutions to this system in any dimension is proved, and it is also shown…

Analysis of PDEs · Mathematics 2020-09-29 Laurent Desvillettes , Valeria Giunta , Jeff Morgan , Bao Quoc Tang

This paper studies the relations among system parameters, uniqueness, and stability of equilibria, for kinetic systems given in the form of polynomial ODEs. Such models are commonly used to describe the dynamics of nonnegative systems, with…

Molecular Networks · Quantitative Biology 2016-11-14 Antonio A. Alonso , Gabor Szederkenyi

We study the related questions: (i) when Feynman amplitudes in massless $\phi^4$ theory evaluate to multiple zeta values, and (ii) when their underlying motives are mixed Tate. More generally, by considering configurations of singular…

Algebraic Geometry · Mathematics 2010-07-21 Francis C. S. Brown

This work addresses whether a reaction network, taken with mass-action kinetics, is multistationary, that is, admits more than one positive steady state in some stoichiometric compatibility class. We build on previous work on the effect…

Molecular Networks · Quantitative Biology 2019-08-27 AmirHosein Sadeghimanesh , Elisenda Feliu

Robustness of biochemical systems has become one of the central questions in systems biology although it is notoriously difficult to formally capture its multifaceted nature. Maintenance of normal system function depends not only on the…

Molecular Networks · Quantitative Biology 2012-03-28 Jost Neigenfind , Sergio Grimbs , Zoran Nikoloski

The calculation of optimal structures in reaction-diffusion models is of great importance in many physicochemical systems. We propose here a simple method to monitor the number of interphases for long times by using a boundary flux…

Chemical Physics · Physics 2014-03-06 Jean-Paul Chehab , Alejandro A. Franco , Youcef Mammeri

Network models are widely used as structural summaries of biochemical systems. Statistical estimation of networks is usually based on linear or discrete models. However, the dynamics of these systems are generally nonlinear, suggesting that…

Applications · Statistics 2014-06-03 C. J. Oates , F. Dondelinger , N. Bayani , J. Korola , J. W. Gray , S. Mukherjee

A recent article by Weidner et al. [2021] presents a method to extract graph properties that are predictive of the dynamical behavior of multivariate, discrete models of biochemical regulation. In other words, a method that uses only…

Quantitative Methods · Quantitative Biology 2021-10-22 Luis M. Rocha

In this work, we propose a global model selection criterion to estimate the graph of conditional dependencies of a random vector based on a finite sample. By global criterion, we mean optimizing a function over the entire set of possible…

Statistics Theory · Mathematics 2023-11-06 Florencia Leonardi , Magno T. F Severino

Chemical reaction networks are often used to model and understand biological processes such as cell signaling. Under the framework of chemical reaction network theory, a process is modeled with a directed graph and a choice of kinetics,…

Combinatorics · Mathematics 2020-12-07 Mark Curiel , Elizabeth Gross , Carlos Munoz

We further clarify the relation between detailed-balanced and complex-balanced equilibria of reversible chemical reaction networks. Our results hold for arbitrary kinetics and also for boundary equilibria. Detailed balance, complex balance,…

Dynamical Systems · Mathematics 2020-09-29 Stefan Müller , Badal Joshi

We consider quantum search on graphs. Recently, it has been shown that the graph properties like connectivity, global symmetry, or regularity cannot serve as a reliable criteria that must be satisfied by a graph to allow a successful…

Quantum Physics · Physics 2016-05-18 Avatar Tulsi

A class of chemical reaction networks is described with the property that each positive equilibrium is locally asymptotically stable relative to its stoichiometry class, an invariant subspace on which it lies. The reaction systems treated…

Dynamical Systems · Mathematics 2013-04-11 Pete Donnell , Murad Banaji

Risk classification plays an important role in many regulations and standards. However, a general method that provides an optimal classification has not been proposed yet. Also, the criteria of optimality are not defined in these…

Discrete Mathematics · Computer Science 2020-12-29 Daniel Zentai

Chemical equilibrium is fully characterized by thermodynamics, while the rates of chemical reactions can be calculated for ideal solutions by using mass-action equations. The evaluation of the rates of reactions in a non-ideal system is…

Chemical Physics · Physics 2025-01-20 Doriano Brogioli , Fabio La Mantia

Chemical reaction networks with generalized mass-action kinetics lead to power-law dynamical systems. As a simple example, we consider the Lotka reactions with two chemical species and arbitrary power-law kinetics. We study existence,…

Dynamical Systems · Mathematics 2022-09-14 Balázs Boros , Josef Hofbauer , Stefan Müller
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