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Most biomolecules occur in mirror, or chiral, images of each other. However, life is homochiral: proteins contain almost exclusively levorotatory (L) amino acids, while only dextrorotatory (R) sugars appear in RNA and DNA. The mechanism…

Astrophysics · Physics 2009-06-23 Marcelo Gleiser , Joel Thorarinson , Sara Imari Walker

Understanding the origin and long-term evolution of the Solar System is a fundamental goal of planetary science and astrophysics. This chapter describes our current understanding of the key processes that shaped our planetary system,…

Earth and Planetary Astrophysics · Physics 2024-04-24 Sean N. Raymond

Reaction-diffusion equations based on a polymerization model are solved to simulate the spreading of hypothetic left and right handed life forms on the Earth's surface. The equations exhibit front-like behavior as is familiar from the…

Biomolecules · Quantitative Biology 2007-05-23 Axel Brandenburg , Tuomas Multamäki

The topology of the universe is discussed in relation to the singularity problem. We explore the possibility that the initial state of the universe might have had a structure with 3-Klein bottle topology, which would lead to a model of a…

General Physics · Physics 2009-01-23 V. N. Yershov

The relevance of chaos to evolution is discussed in the context of the origin and maintenance of diversity and complexity. Evolution to the edge of chaos is demonstrated in an imitation game. As an origin of diversity, dynamic clustering of…

adap-org · Physics 2008-02-03 Kunihiko Kaneko

The problem of the rate and mechanisms of biological evolution was considered. It was shown that species could not be formed due to undirected mutations in characteristic times of about one million years. A mechanism of deterministic…

Populations and Evolution · Quantitative Biology 2007-05-23 Alexey V. Melkikh

Why are life trajectories difficult to predict? We investigated this question through in-depth qualitative interviews with 40 families sampled from a multi-decade longitudinal study. Our sampling and interviewing process were informed by…

A theoretical study of cell evolution is presented here. By using a toolbox containing an intracellular catalytic reaction network model and a mutation-selection process, four distinct phases of self-organization were unveiled. First, the…

Biological Physics · Physics 2022-01-26 V. Ibarra-Junquera , D. Radillo-Ochoa , C. A. Terrero-Escalante

Statistical and mathematical modeling are crucial to describe, interpret, compare and predict the behavior of complex biological systems including the organization of hematopoietic stem and progenitor cells in the bone marrow environment.…

Quantitative Methods · Quantitative Biology 2018-09-07 Walter de Back , Thomas Zerjatke , Ingo Roeder

The oft-repeated claim that life is written into the laws of nature are examined and criticized. Arguments are given in favour of life spreading between near-neighbour planets in rocky impact ejecta (transpermia), but against panspermia,…

Astrophysics · Physics 2007-05-23 P. C. W. Davies

The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our…

Populations and Evolution · Quantitative Biology 2022-07-18 Ivan Ivanov , Stoyan K. Smoukov , Ehsan Nourafkan , Katharina Landfester , Petra Schwille

Eukaryotic cells and intracellular pathogens such as bacteria or viruses utilize the actin polymerization machinery to propel themselves forward. Thereby, the onset of motion and choice of direction may be the result of a spontaneous…

Soft Condensed Matter · Physics 2009-09-04 Karin John , Denis Caillerie , Philippe Peyla , Mourad Ismail , Annie Raoult , Jacques Prost

The evolutionary biology of aging is fundamental to understanding the mechanisms of aging and how to develop anti-aging treatments. Thus far most evolutionary theory concerns the genetics of aging with limited physiological integration.…

Populations and Evolution · Quantitative Biology 2025-09-22 Mirre J P Simons , Marc Tatar

In the past century many fundamental results on unpredictability, undecidability and uncertainty have compelled scientists to grapple with the idea that some questions may never be resolved within our current theories. While this…

History and Philosophy of Physics · Physics 2020-05-19 Fabien Paillusson , Matthew Booth

Over the billions of years since the Big Bang, the lives, deaths and afterlives of stars have enriched the Universe in the heavy elements that make up so much of ourselves and our world. This review summarizes the methods used to evolve…

Astrophysics · Physics 2016-08-30 W. R. Hix , B. S. Meyer

Over the past two decades, the rapid surge in data-intensive computational techniques for statistical modeling may have had the effect of diminishing the use of applied mathematics in causal scientific inquiry. In this paper, co-authored by…

History and Philosophy of Physics · Physics 2026-05-13 Marzieh Asgari-Targhi , Amene Asgari-Targhi , Mahboubeh Asgari-Targhi , Edward J. , Hall

A reliable understanding of the Earth system is essential for the life quality of modern society. Natural hazards are the cause of most life and resource losses. The ability to define the conditions for a sustainable development of…

Chaotic Dynamics · Physics 2025-04-08 Jürgen Kurths , Ankit Agarwal , Ugur Öztürk , Shubham Sharma , Norbert Marwan , Deniz Eroglu

In view of ever-changing conditions both in the external world and in intrinsic brain states, maintaining the robustness of computations poses a challenge, adequate solutions to which we are only beginning to understand. At the level of…

Neurons and Cognition · Quantitative Biology 2022-03-29 Nelson Niemeyer , Jan-Hendrik Schleimer , Susanne Schreiber

The well-defined but intricate course of time evolution exhibited by many naturally occurring phenomena suggests some source of dynamic order sustaining it. In spite of its obviousness as a problem, it has remained absent from the…

Adaptation and Self-Organizing Systems · Physics 2021-03-02 R. Herrero , J. Farjas , F. Pi , G. Orriols