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Acknowledging the ever-increasing demand for composites in the engineering industry, this paper focuses on the failure of composites at the microscale and augmenting the use of multiscale modelling techniques to make them better for various…

Computational Engineering, Finance, and Science · Computer Science 2025-08-14 Hari Sankar R , Harpreet Singh

With potential relevance to biomechanics, an interesting problem in statistical mechanics not previously solved is a binary mechanical model system. Discrete chemical states of proteins are often associated with discrete metastable…

Statistical Mechanics · Physics 2025-01-22 Josh E. Baker

Characterizing the connection between material design decisions/parameters and their effective properties allows for accelerated materials development and optimization. We present a global sensitivity analysis of woven composite…

Computational Engineering, Finance, and Science · Computer Science 2021-04-29 Lincoln N. Collins , Scott A. Roberts

The MechElastic Python package evaluates the mechanical and elastic properties of bulk and 2D materials using the elastic coefficient matrix ($C_{ij}$) obtained from any ab-initio density-functional theory (DFT) code. The current version of…

This paper presents a comprehensive approach to the evaluation of macroscopic material parameters for natural stone and quarry masonry. To that end, a reliable non-linear material model on a meso-scale is developed to cover the random…

Materials Science · Physics 2008-09-16 J. Sejnoha , M. Sejnoha , J. Zeman , J. Sykora , J. Vorel

Knowledge of the mechanical properties of materials is required for the design and analysis of engineering products, however, the characterisation of heterogeneous properties using traditional techniques is limited by spatial resolution or…

Computational Engineering, Finance, and Science · Computer Science 2026-03-16 Robert Hamill , Allan Harte , Aleksander Marek , Fabrice Pierron

The molecular arrangement of lipids and proteins within biomembranes and monolayers gives rise to complex film morphologies as well as regions of distinct electrical surface potential, topographical and electrostatic nanoscale domains. To…

Soft Condensed Matter · Physics 2016-11-28 Elizabeth Drolle , W. F. D. Bennett , K. Hammond , Edward Lyman , Mikko Karttunen , Zoya Leonenko

Phase-segregated polyureas (PU) have received considerable interest due to their use as tough, impact-resistant coatings. Polyureas are favored for these applications due to their mechanical strain rate sensitivity and energy dissipation.…

Materials Science · Physics 2023-10-03 Steven J. Yang , Stephanie I. Rosenbloom , Brett P. Fors , Meredith N. Silberstein

We discuss Bayesian inference (BI) for the probabilistic identification of material parameters. This contribution aims to shed light on the use of BI for the identification of elastoplastic material parameters. For this purpose a single…

Computational Engineering, Finance, and Science · Computer Science 2017-01-17 Hussein Rappel , Lars A. A. Beex , Jack S. Hale , Stephane P. A. Bordas

The local structure of a protein strongly impacts its function and interactions with other molecules. Therefore, a concise, informative representation of a local protein environment is essential for modeling and designing proteins and…

Protein function prediction is dominated by representations grounded in sequence and static structure, neither of which captures the collective vibrational dynamics through which proteins act. Here we introduce frequency-space mechanics, a…

Biomolecules · Quantitative Biology 2026-05-15 Charles B Reilly

Advanced modern technology and industrial sustainability theme have contributed implementing composite materials for various industrial applications. Green composites are among the desired alternatives for the green products. However, to…

Neural and Evolutionary Computing · Computer Science 2024-04-12 Faris M. AL-Oqla , Hossam Faris , Maria Habib , Pedro A. Castillo-Valdivieso

Proteins are fundamental biological entities mediating key roles in cellular function and disease. This paper introduces a multi-scale graph construction of a protein -- HoloProt -- connecting surface to structure and sequence. The surface…

Machine Learning · Computer Science 2022-04-06 Vignesh Ram Somnath , Charlotte Bunne , Andreas Krause

Continuum models of active nematic gels have proved successful to describe a number of biological systems consisting of a population of rodlike motile subunits in a fluid environment. However, in order to get a thorough understanding of the…

Soft Condensed Matter · Physics 2023-05-03 Stefano Turzi

Allosteric regulation in proteins is often accompanied by conformational changes that facilitate transmission of mechanical signals between distant ligand binding sites. Typically, these deformations are classified in terms of specific…

Soft Condensed Matter · Physics 2024-01-26 Jason W. Rocks , Eleni Katifori , Andrea J. Liu

Synthesis of protein molecules in a cell are carried out by ribosomes. A ribosome can be regarded as a molecular motor which utilizes the input chemical energy to move on a messenger RNA (mRNA) track that also serves as a template for the…

Biological Physics · Physics 2009-07-12 Ashok Garai , Debanjan Chowdhury , Debashish Chowdhury , T. V. Ramakrishnan

Mechanochemical models of pattern formation in biological tissues have been used to study a variety of biomedical systems and describe the physical interactions between cells and their local surroundings. These models generally consist of a…

Tissues and Organs · Quantitative Biology 2021-05-12 Chiara Villa , Mark A. J. Chaplain , Alf Gerisch , Tommaso Lorenzi

Metamaterials exhibit materials response deviation from conventional elasticity. This phenomenon is captured by the generalized elasticity as a result of extending the theory at the expense of introducing additional parameters. These…

Computational Engineering, Finance, and Science · Computer Science 2021-06-10 Bilen Emek Abali , Emilio Barchiesi

Despite the significant increase in computational power, molecular modeling of protein structure using classical all-atom approaches remains inefficient, at least for most of the protein targets in the focus of biomedical research. Perhaps…

Biomolecules · Quantitative Biology 2016-11-01 Sebastian Kmiecik , Andrzej Kolinski

Nanoporous materials are characterized by their complex porous morphology illustrated by the presence of a solid network and voids. The fraction of these voids is characterized by the porosity of the structure, which influences the bulk…

Materials Science · Physics 2024-10-08 Rajesh Chandrasekaran , Mikhail Itskov , Ameya Rege