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We propose Radiation Exposure Theory (RET), a mathematical framework to estimate biological damage caused by irradiation. This is an extension of LDM model which was proposed in the paper [Y. Manabe et al.: J. Phys. Soc. Jpn. 81,…

Biological Physics · Physics 2014-11-18 Yuichiro Manabe , Masako Bando

Differential expression (DE) plays a fundamental role toward illuminating the molecular mechanisms driving a difference between groups (e.g., due to treatment or disease). While any analysis is run on particular cells/samples, the intent is…

Quantitative Methods · Quantitative Biology 2023-12-12 Miriam Shiffman , Ryan Giordano , Tamara Broderick

We outline a planned experiment to investigate if personal data (e.g., demographics and behavioral patterns) can be used to selectively expose individuals to disinformation such that an adversary can spread disinformation more efficiently…

Cryptography and Security · Computer Science 2023-06-09 Protik Bose Pranto , Waqar Hassan Khan , Sahar Abdelnabi , Rebecca Weil , Mario Fritz , Rakibul Hasan

Radiation chemistry of model systems irradiated with ultra-high dose-rates (UHDR) is key to obtain a mechanistic understanding of the sparing of healthy tissue, which is called the FLASH effect. It is envisioned to be used for efficient…

Medical Physics · Physics 2025-11-03 Marc Benjamin Hahn

False discovery rate (FDR) procedures provide misleading inference when testing multiple null hypotheses with heterogeneous multinomial data. For example, in the motivating study the goal is to identify species of bacteria near the roots of…

Methodology · Statistics 2015-11-05 Joshua Habiger , David Watts , Michael Anderson

Two models are introduced to investigate graph matching in the presence of corrupt nodes. The weak model, inspired by biological networks, allows one or both networks to have a positive fraction of molecular entities interact randomly with…

Statistics Theory · Mathematics 2023-11-02 Taha Ameen , Bruce Hajek

Studies using assays to quantify the expression of thousands of genes on tens to thousands of cell samples have been carried out for over 20 years. Such assays are based on microarrays, DNA sequencing or other molecular technologies. All…

Statistics Theory · Mathematics 2025-06-18 Jiming Jiang , Johann A. Gagnon-Bartsch , Terence P. Speed

During operation, the radio-frequency quadrupole (RFQ) of the LINAC4 at CERN is exposed to high electric fields, which can lead to vacuum breakdown. It is also subject to beam loss, which can cause surface modification, including…

The failure mode of the phone falling has a lot to do with the ground material. At present, the research on ground material and mobile phone damage is generally carried out through experiments, which is extremely costly. This paper presents…

Systems and Control · Electrical Eng. & Systems 2024-06-14 Xuesong Wang

Recent work has shown that cell phone mobility data has the unique potential to create accurate models for human mobility and consequently the spread of infected diseases. While prior studies have exclusively relied on a mobile network…

Cryptography and Security · Computer Science 2022-06-14 Alexandros Bampoulidis , Alessandro Bruni , Lukas Helminger , Daniel Kales , Christian Rechberger , Roman Walch

The cell biology literature is littered with erroneously tiny P values, often the result of evaluating individual cells as independent samples. Because readers use P values and error bars to infer whether a reported difference would likely…

Other Quantitative Biology · Quantitative Biology 2020-04-30 Samuel J. Lord , Katrina B. Velle , R. Dyche Mullins , Lillian K. Fritz-Laylin

As data is a central component of many modern systems, the cause of a system malfunction may reside in the data, and, specifically, particular properties of the data. For example, a health-monitoring system that is designed under the…

Health economic evaluations face the issues of non-compliance and missing data. Here, non-compliance is defined as non-adherence to a specific treatment, and occurs within randomised controlled trials (RCTs) when participants depart from…

Applications · Statistics 2019-02-26 Karla DiazOrdaz , Richard Grieve

Over the last few years, several major scientific fraud cases have shocked the scientific community. The number of retractions each year has also increased tremendously, especially in the biomedical field, and scientific misconduct accounts…

Digital Libraries · Computer Science 2016-02-25 Philippe Mongeon , Vincent Lariviere

Research stands as a pivotal factor in propelling the progress of any nation forward. However, if tainted by misconduct, it poses a significant threat to the nation's development. This study aims to scrutinize various cases of deliberate…

Digital Libraries · Computer Science 2024-04-25 Kiran Sharma

The highly energetic electrons in a transmission electron microscope (TEM) can alter or even completely destroy the structure of samples before sufficient information can be obtained. This is especially problematic in the case of zeolites,…

Materials Science · Physics 2021-05-05 Abner Velazco , Daen Jannis , Armand Béché , Johan Verbeeck

Novel aspects of human dynamics and social interactions are investigated by means of mobile phone data. Using extensive phone records resolved in both time and space, we study the mean collective behavior at large scales and focus on the…

Physics and Society · Physics 2009-11-13 J. Candia , M. C. González , P. Wang , T. Schoenharl , G. Madey , A. -L. Barabási

Extremely low frequency electromagnetic fields aren't considered as a real carcinogenic agent despite the fact that some studies have showed impairment of the DNA integrity in different cells lines. The aim of this study was evaluation of…

Subcellular Processes · Quantitative Biology 2013-01-24 Cosmin Teodor Miha , Gabriela Vochita , Florin Brinza , Pincu Rotinberg

Much evidence in comparative effectiveness research is based on observational studies. Researchers who conduct observational studies typically assume that there are no unobservable differences between the treated and control groups.…

Applications · Statistics 2020-01-23 Luke Keele , Stephen O'Neill , Richard Grieve

As 3GPP systems have strengthened security at the upper layers of the cellular stack, plaintext PHY and MAC layers have remained relatively understudied, though interest in them is growing. In this work, we explore lower-layer exploitation…

Cryptography and Security · Computer Science 2026-02-12 Subangkar Karmaker Shanto , Imtiaz Karim , Elisa Bertino
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