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Related papers: Permeation as a Diffusion Process

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A simple theory of ion permeation through a channel is presented, in which diffusion occurs according to Fick's law and drift according to Ohm's law, in the electric field determined by all the charges present. This theory accounts for…

Biomolecules · Quantitative Biology 2016-10-17 Bob Eisenberg

We consider a simple working hypothesis that all permeation properties of open ionic channels can be predicted by understanding electrodiffusion in fixed structures, without invoking conformation changes, or changes in chemical bonds. We…

Biomolecules · Quantitative Biology 2015-03-17 Bob Eisenberg

This is an early but comprehensive review of the PNP Poisson Nernst Planck theory of ion channels. Extensive reference is made to the earlier literature. The starting place for this theory of open channels is a theory of electrodiffusion…

Biomolecules · Quantitative Biology 2010-09-16 Bob Eisenberg

Ions transiting biomembranes might pass readily from water through ion-specific membrane proteins if those protein channels provide environments similar to the aqueous solution hydration environment. Indeed, bulk aqueous solution is an…

Chemical Physics · Physics 2019-12-10 Mangesh I. Chaudhari , Juan M. Vanegas , L. R. Pratt , Ajay Muralidharan , Susan B. Rempe

Motivated by experiments in which a polynucleotide is driven through a proteinaceous pore by an electric field, we study the diffusive motion of a polymer threaded through a narrow channel with which it may have strong interactions. We show…

Biological Physics · Physics 2009-10-31 David K. Lubensky , David R. Nelson

Diffusion of colored dye on water saturated paper substrates has been traditionally exploited with great skill by renowned water color artists. The same physics finds more recent practical applications in paper based diagnostic devices…

Soft Condensed Matter · Physics 2020-02-27 Sankha Shuvra Das , Sumeet Kumar , Sambuddha Ghosal , Sandip Ghosal , Suman Chakraborty

The interpretation electrical phenomena in biomembranes is usually based on the assumption that the experimentally found discrete ion conduction events are due to a particular class of proteins called ion channels while the lipid membrane…

Biological Physics · Physics 2010-06-17 Thomas Heimburg

Past work has shown that ions can pass through a membrane more readily in one direction than the other. We demonstrate here in a model and an experiment that for a mixture of small and large particles such asymmetric diffusion can arise…

Soft Condensed Matter · Physics 2009-11-13 Robert S. Shaw , Norman Packard , Matthias Schröter , Harry L. Swinney

The consistent description of kinetic and hydrodynamic processes is applied to the study of ion transport processes in the ionic solution-porous medium system. A system of equations is obtained for the nonequilibrium single-ion distribution…

Statistical Mechanics · Physics 2025-06-26 P. P. Kostrobij , B. M. Markovych , O. V. Viznovych , M. V. Tokarchuk

We propose an analytical model based on diffusion-reaction equation approach for electrochemical electron transfer reaction, where the rate is limited by the electron transfer process. The electron transfer from an ion in solution to the…

Other Condensed Matter · Physics 2015-05-29 Aniruddha Chakraborty

Diffusion rates through a membrane can be asymmetric, if the diffusing particles are spatially extended and the pores in the membrane have asymmetric structure. This phenomenon is demonstrated here via a deterministic simulation of a…

Statistical Mechanics · Physics 2007-05-23 Norman Packard , Rob Shaw

We examine the dependence of the physical quantities of the rotatory molecular motor, such as the rotation velocity and the proton translocation rate, on the chemical reaction rate using the model based only on diffusion process. A peculiar…

Biological Physics · Physics 2009-11-10 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

We discuss various models of ion transport through cell membrane channels. Recent experimental data shows that sizes of ion channels are compared to those of ions and that only few ions may be simultaneously in any single channel.…

Subcellular Processes · Quantitative Biology 2007-06-06 Jan Gomulkiewicz , Jacek Miekisz , Stanislaw Miekisz

Diffusion is the result of repeated random scattering. It governs a wide range of phenomena from Brownian motion, to heat flow through window panes, neutron flux in fuel rods, dispersion of light in human tissue, and electronic conduction.…

Mesoscale and Nanoscale Physics · Physics 2018-07-04 Zhou Shi , Azriel Z. Genack

We consider processes that coincide with a given diffusion process except on the boundaries of a finite collection of domains. The behavior on each of the boundaries is asymmetric: the process is much more likely to enter the interior of…

Probability · Mathematics 2020-03-18 Mark Freidlin , Leonid Koralov

The problem of the diffusion evolution of a pore filled with molecular hydrogen in a spherical granule in a hydrogen medium is solved. The initial position of the pore is displaced relative to the center of the granule. A nonlinear system…

Mesoscale and Nanoscale Physics · Physics 2022-03-31 M. I. Kopp , P. N. Ostapchuk , V. V. Yanovsky

Diffusion of transported particles in the intracellular medium is described by means of a generalized diffusion equation containing forces due to the cytoskeleton network and to the protein motors. We find that the enhanced diffusion…

Soft Condensed Matter · Physics 2009-02-05 I. Santamaria-Holek , M. H. Vainstein , J. M. Rubi , F. A. Oliveira

We use coarse grained molecular dynamics simulations to investigate diffusion properties of sheared lipid membranes with embedded transmembrane proteins. In membranes without proteins, we find normal in-plane diffusion of lipids in all flow…

Biological Physics · Physics 2013-09-10 Atefeh Khoshnood , Mir Abbas Jalali

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

We give a probabilistic representation of a one-dimensional diffusion equation where the solution is discontinuous at $0$ with a jump proportional to its flux. This kind of interface condition is usually seen as a semi-permeable barrier.…

Probability · Mathematics 2016-06-28 Antoine Lejay
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