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The Fluid Mosaic Model by Singer & Nicolson proposes that biological membranes consist of a fluid lipid layer into which integral proteins are embedded. The lipid membrane acts as a two-dimensional liquid in which the proteins can diffuse…

Biological Physics · Physics 2025-09-29 Thomas Heimburg

A two-component model is developed that consists of a discrete loop of cardiac cells that circulates action potentials together with a cardiac pacing mechanism. Physiological properties of cells such as restitutions of refractoriness and of…

Adaptation and Self-Organizing Systems · Physics 2014-01-16 H. Sedaghat , M. A. Wood , J. W. Cain , C-K. Cheng , C. M. Baumgarten , D. M. Chan

This paper proposes a new design for realizing grounded and floating meminductor emulators built with two operational transconductance amplifiers (OTAs) and two second-generation current conveyors. The proposed grounded and floating…

Signal Processing · Electrical Eng. & Systems 2024-01-15 Garima Shukla , Pratik Kumar , Sajal K. Paul

We suggest electronic circuits with memristors (resistors with memory) that operate as memcapacitors (capacitors with memory) and meminductors (inductors with memory). Using a memristor emulator, the suggested circuits have been built and…

Instrumentation and Detectors · Physics 2014-11-20 Yuriy V. Pershin , Massimiliano Di Ventra

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

Medical Physics · Physics 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

According to the conventional approach to model neural ensembles the extracellular environment has fixed ionic concentrations. However, in many cases the extracellular concentration of potassium ions can not be regarded as constant. That…

Disordered Systems and Neural Networks · Physics 2015-05-13 D. E. Postnov , F. Müller , R. B. Schuppner , L. Schimansky-Geier

In this work, we present a computational formulation based on continuum mechanics to study the interaction of fluid membranes embedded with semiflexible filaments. This is motivated by systems in membrane biology, such as cytoskeletal…

Numerical Analysis · Mathematics 2023-12-21 Basant Lal Sharma , Luigi E. Perotti , Sanjay Dharmavaram

We study patterns of partial synchronization in a network of FitzHugh-Nagumo oscillators with empirical structural connectivity measured in human subjects. We report the spontaneous occurrence of synchronization phenomena that closely…

Adaptation and Self-Organizing Systems · Physics 2021-02-03 M. Gerster , R. Berner , J. Sawicki , A. Zakharova , A. Škoch , J. Hlinka , K. Lehnertz , E. Schöll

Objective: Traumatic brain injuries and damage are major causes of death and disability. We propose a 3D fully coupled electro-mechanical model of a nerve bundle to investigate the electrophysiological impairments due to trauma at the…

Biological Physics · Physics 2020-09-02 Ilaria Cinelli , Michel Destrade , Maeve Duffy , Peter McHugh

Electrocardiogram (ECG)-based models have achieved strong performance in diagnostic tasks, yet they remain limited in modeling how cardiac dynamics evolve under external interventions. In particular, existing approaches focus primarily on…

Artificial Intelligence · Computer Science 2026-05-19 Zhikang Chen , Yue Wang , Sen Cui , Yu Zhang , Changshui Zhang , Tianling Ren , Tingting Zhu

Extreme events occur in many spatially extended dynamical systems, often devastatingly affecting human life which makes their reliable prediction and efficient prevention highly desirable. We study the prediction and prevention of extreme…

Data Analysis, Statistics and Probability · Physics 2015-10-09 Stephan Bialonski , Gerrit Ansmann , Holger Kantz

In the following, we discuss nonlinear simulations of nonlinear dynamical systems, which are applied in technical and biological models. We deal with different ideas to overcome the treatment of the nonlinearities and discuss a novel…

Numerical Analysis · Mathematics 2014-12-01 Juergen Geiser , Vahid Yaghoubi

A theoretical model of a two-component fluid membrane containing lipids and two-state active inclusions is presented. Under strong inclusion activities the membrane can be unstable due to pump-driven undulation or aggregation of high…

Soft Condensed Matter · Physics 2009-11-10 Hsuan-Yi Chen

Multiphase systems are ubiquitous in engineering, biology, and materials science, where understanding their complex interactions and rheological behavior is crucial for advancing applications ranging from emulsion stability to cellular…

Fluid Dynamics · Physics 2025-10-27 Andres Santiago Espinosa-Moreno , Nicolas Moreno , Marco Ellero

In exploring the simulation of human rhythmic perception and synchronization capabilities, this study introduces a computational model inspired by the physical and biological processes underlying rhythm processing. Utilizing a reservoir…

Neurons and Cognition · Quantitative Biology 2025-03-28 Zhongju Yuan , Wannes Van Ransbeeck , Geraint Wiggins , Dick Botteldooren

In this paper, we show that the dynamics of a wide variety of nonlinear systems such as engineering, physical, chemical, biological, and ecological systems, can be simulated or modeled by the dynamics of memristor circuits. It has the…

Chaotic Dynamics · Physics 2019-02-22 Makoto Itoh

In this paper, we derive an effective model for transport processes in periodically perforated elastic media, taking into account, e.g., cyclic elastic deformations as they occur in lung tissue due to respiratory movement. The underlying…

Analysis of PDEs · Mathematics 2022-06-15 Jonas Knoch , Markus Gahn , Maria Neuss-Radu , Nicolas Neuß

The construction of biologically plausible models of neural circuits is crucial for understanding the computational properties of the nervous system. Constructing functional networks composed of separate excitatory and inhibitory neurons…

Disordered Systems and Neural Networks · Physics 2020-07-01 Alessandro Ingrosso , L. F. Abbott

Local periodic perturbations induce frequency-dependent propagation waves in an excitable spatio-temporally chaotic system. We show how segments of noise-contaminated and chaotic perturbations induce characteristic sequences of excitations…

Chaotic Dynamics · Physics 2009-11-10 Gerold Baier , Markus Muller

In this, the third paper in our series describing the excitations of the higher lattice gauge theory model for topological phases, we will examine the 3+1d case in detail. We will explicitly construct the ribbon and membrane operators which…

Strongly Correlated Electrons · Physics 2024-02-20 Joe Huxford , Steven H. Simon