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We study the homogenization of a novel microscopic tridomain system, allowing for a more detailed analysis of the properties of cardiac conduction than the classical bidomain and monodomain models. In (Acta Appl.Math. 179 (2022) 1--35), we…

Analysis of PDEs · Mathematics 2022-09-16 Fakhrielddine Bader , Mostafa Bendahmane , Mazen Saad , Raafat Talhouk

Clinical oriented applications of computational electrocardiology require efficient and reliable identification of patient-specific parameters of mathematical models based on available measures. In particular, the estimation of cardiac…

Numerical Analysis · Mathematics 2016-11-01 Huanhuan Yang , Alessandro Veneziani

This letter investigates the uplink of a multi-user millimeter wave (mmWave) system, where the base station (BS) is equipped with a massive multiple-input multiple-output (MIMO) array and resolution-adaptive analog-to-digital converters…

Signal Processing · Electrical Eng. & Systems 2020-05-19 Hualian Sheng , Xihan Chen , Xiongfei Zhai , An Liu , Min-Jian Zhao

We present a new, high-performance coupled electrodynamics-micromagnetics solver for full physical modeling of signals in microelectronic circuitry. The overall strategy couples a finite-difference time-domain (FDTD) approach for Maxwell's…

Computational Physics · Physics 2021-03-25 Zhi Yao , Revathi Jambunathan , Yadong Zeng , Andrew Nonaka

To a large extent, the stiffness of the bidomain and monodomain models depends on the choice of the ionic model, which varies in terms of complexity and realism. In this paper, we compare and analyze a variety of time-stepping methods:…

Numerical Analysis · Mathematics 2020-06-05 Thomas Roy , Yves Bourgault , Charles Pierre

The refractory period of cardiac tissue can be quantitatively described using strength-interval (SI) curves. The information captured in SI curves is pertinent to the design of anti-arrhythmic devices including pacemakers and implantable…

Numerical Analysis · Mathematics 2023-04-11 Joyce Reimer , Sebastián A. Domínguez-Rivera , Joakim Sundnes , Raymond J. Spiteri

We present the meshfree Mixed Collocation Method (MCM) to solve the monodomain model for numerical simulation of cardiac electrophysiology. We apply MCM to simulate cardiac electrical propagation in 2D tissue sheets and 3D tissue slabs as…

Numerical Analysis · Mathematics 2021-10-14 Konstantinos A. Mountris , Esther Pueyo

In this paper we consider the monodomain model of cardiac electrophysiology. After an analysis of the well-posedness of the model, we determine an asymptotic expansion of the perturbed potential due to the presence of small conductivity…

Analysis of PDEs · Mathematics 2020-10-28 Elena Beretta , Cecilia Cavaterra , Luca Ratti

Many physical systems are governed by ordinary or partial differential equations (see, for example, Chapter ''Differential equations'', ''System of Differential Equations''). Typically the solution of such systems are functions of time or…

Numerical Analysis · Mathematics 2023-09-06 Clarissa Astuto , Giovanni Russo

The eikonal equation has become an indispensable tool for modeling cardiac electrical activation accurately and efficiently. In principle, by matching clinically recorded and eikonal-based electrocardiograms (ECGs), it is possible to build…

Optimization and Control · Mathematics 2023-12-06 Thomas Grandits , Jan Verhülsdonk , Gundolf Haase , Alexander Effland , Simone Pezzuto

We present a novel approach aimed at high-performance uncertainty quantification for time-dependent problems governed by partial differential equations. In particular, we consider input uncertainties described by a Karhunen-Loeeve expansion…

Computational Engineering, Finance, and Science · Computer Science 2021-02-05 Seif Ben Bader , Pietro Benedusi , Alessio Quaglino , Patrick Zulian , Rolf Krause

In this paper the Micro-Macro Parareal algorithm was adapted to PDEs. The parallel-in-time approach requires two meshes of different spatial resolution in order to compute approximations in an iterative way to a predefined reference…

Numerical Analysis · Mathematics 2023-09-11 Benedict Philippi , Mahfuz Sarker Miraz , Thomas Slawig

Computing the solution of linear systems of equations is invariably the most time consuming task in the numerical solutions of PDEs in many fields of computational science. In this study, we focus on the numerical simulation of…

Computational Physics · Physics 2019-01-24 Jongmin Seo , Daniele E. Schiavazzi , Alison L. Marsden

The present paper aims at providing a numerical strategy to deal with PDE-constrained optimization problems solved with the adjoint method. It is done through out a unified formulation of the constraint PDE and the adjoint model. The…

Optimization and Control · Mathematics 2017-12-01 Gino I. Montecinos , Juan Lopez-Rios , Jaime H. Ortega , Rodrigo Lecaros

In this study, we demonstrate simplified equivalent circuit models to effectively approximate responses of recently reported waveform-selective metasurfaces that distinguish different electromagnetic waves even at the same frequency…

Applied Physics · Physics 2020-05-05 Kosei Asano , Tomoyuki Nakasha , Hiroki Wakatsuchi

In this paper, we find relations between the ionic parameters and the diffusion parameters which are sufficient to ensure the existence of a periodic solution for a well-known monodomain model in a weak sense. We make use of the method of…

Analysis of PDEs · Mathematics 2021-10-06 Andres Fraguela-Collar , Raul Felipe-Sosa , Jacques Henry , Manlio F. Márquez

A space-time adaptive method is presented for the reactive Euler equations describing chemically reacting gas flow where a two species model is used for the chemistry. The governing equations are discretized with a finite volume method and…

Computational Physics · Physics 2019-12-16 Olivier Roussel , Kai Schneider

Efficient multiphysics models that can adapt to the varying complexity of physical processes in space and time are desirable for modeling fluid migration in the subsurface. Vertical equilibrium (VE) models are simplified mathematical models…

Computational Physics · Physics 2018-08-24 Beatrix Becker , Bo Guo , Karl Bandilla , Michael A. Celia , Bernd Flemisch , Rainer Helmig

We propose a time-adaptive predictor/multi-corrector method to solve hyperbolic partial differential equations, based on the generalized-$\alpha$ scheme that provides user-control on the numerical dissipation and second-order accuracy in…

Numerical Analysis · Mathematics 2022-10-11 Nicolas A. Labanda , Pouria Behnoudfar , Victor M. Calo

The multiscale complexity of modern problems in computational science and engineering can prohibit the use of traditional numerical methods in multi-dimensional simulations. Therefore, novel algorithms are required in these situations to…

Numerical Analysis · Mathematics 2021-06-15 Cale Harnish , Luke Dalessandro , Karel Matous , Daniel Livescu