Related papers: Ion irradiation induced direct damage to proteins …
According to the experimental evidence damage induced by densely ionizing radiation in mammalian cells is distributed along the DNA molecule in the form of clusters. The most critical constituent of DNA damage are double-strand breaks…
The mechanical properties of DNA play a critical role in many biological functions. For example, DNA packing in viruses involves confining the viral genome in a volume (the viral capsid) with dimensions that are comparable to the DNA…
Photoactive proteins absorb light and undergo structural changes that enable them to perform essential biological functions. These proteins are critical for understanding light-induced biological processes, making them important in…
In this chapter, we present an overview of sources of biologically relevant astrophysical radiation and effects of that radiation on organisms and their habitats. We consider both electromagnetic and particle radiation, with an emphasis on…
We study the acceleration of heavy nuclei at SNR shocks when the process of ionization is taken into account. Heavy atoms ($Z_N >$ few) in the interstellar medium which start the diffusive shock acceleration (DSA) are never fully ionized at…
The various aspects of antiproton physics are shortly reviewed, and its relevance for the possible discovery of new particles and effects is pointed out. Then a survey of the nucleon-antinucleon interactions is given. In the…
Two different zinc oxide nanoparticles, as well as zinc ions, are used to study the cellular responses of the RAW 264 macrophage cell line. A proteomic screen is used to provide a wide view of the molecular effects of zinc, and the most…
Ab-initio numerical study of collisionless shocks in electron-ion unmagnetized plasmas is performed with fully relativistic particle in cell simulations. The main properties of the shock are shown, focusing on the implications for particle…
In order to study the molecular damage induced in the form of single-strand and double-strand breaks by the ionizing radiation at the DNA level, Geant4-DNA Monte Carlo simulation code for complete transportation of primary protons and other…
Changes in the medium of biological cell nucleus under ion beam action is considered as a possible cause of cell functioning disruption in the living body. As the most long-lived molecular product appeared in the cell after the passage of…
The pattern of radiation energy deposition in substances at the microscopic level of lattice, molecule size, or the cell's nucleus is not uniform. The energy of radiation is transferred to the substance medium in the form of discrete,…
Electron-impact ionization of an atom or ion in the presence of a neighboring atom is studied. The latter is first collisionally excited by the incident electron, whose energy is assumed to be high but nonrelativistic. Afterwards, the…
Purpose: To present a closed formalism calculating charged particle radiation damage induced in DNA. The formalism is valid for all types of charged particles and due to its closed nature is suited to provide fast conversion of dose to…
It is a fascinating subject to explore how well we can understand the processes of life on the basis of fundamental laws of physics. It is emphasised that viewing biological processes as manipulation of information extracts their essential…
Astrophysical ionizing radiation events have been recognized as a potential threat to life on Earth, primarily through depletion of stratospheric ozone and subsequent increase in surface-level solar ultraviolet radiation. Simulations of the…
We show that the secondary electrons ejected from the ionization of heavy ions can be injected into the acceleration process that occurs at supernova remnant shocks. This electron injection mechanism works since ions are ionized during the…
Proteins are a matter of dual nature. As a physical object, a protein molecule is a folded chain of amino acids with multifarious biochemistry. But it is also an instantiation along an evolutionary trajectory determined by the function…
Astrophysical ionizing radiation events such as supernovae, gamma-ray bursts, and solar proton events have been recognized as a potential threat to life on Earth, primarily through depletion of stratospheric ozone and subsequent increase in…
Photoionization and its inverse, electron-ion recombination, are key processes that influence many astrophysical plasmas (and gasses), and the diagnostics that we use to analyse the plasmas. In this review we provide a brief overview of the…
The production of peroxide and superoxide is an inevitable consequence of aerobic metabolism, and while these particular "reactive oxygen species" (ROSs) can exhibit a number of biological effects, they are not of themselves excessively…