English
Related papers

Related papers: Ion irradiation induced direct damage to DNA

200 papers

The highly energetic electrons in a transmission electron microscope (TEM) can alter or even completely destroy the structure of samples before sufficient information can be obtained. This is especially problematic in the case of zeolites,…

Materials Science · Physics 2021-05-05 Abner Velazco , Daen Jannis , Armand Béché , Johan Verbeeck

We study the effects of the shear force on the rupture mechanism on a double stranded DNA. Motivated by recent experiments, we perform the atomistic simulations with explicit solvent to obtain the distributions of extension in hydrogen and…

Soft Condensed Matter · Physics 2015-06-17 S. Nath , T. Modi , R. K. Mishra , D. Giri , B. P. Mandal , S. Kumar

By representing damage induction by ionizing particles and its repair by the cell, the probabilistic two-stage model provides a detailed description of the main processes involved in cell killing by radiation. To link this model with issues…

Biological Physics · Physics 2016-08-16 Pavel Kundrát

$TiO_{2}$ nanoparticles (NPs) are widely used in the environmental engineering, medicine, chemical and food industries due to their unique photocatalytic and biocidal properties. NPs may generate reactive oxygen species and, hence, have the…

Biological Physics · Physics 2022-09-28 Evgeniya Usenko , Alexander Glamazda , Vladimir Valeev , Victor Karachevtsev

Radiation damage in biological systems by ionizing radiation is predominantly caused by secondary processes such as charge and energy transfer leading to the breaking of bonds in DNA. Here, we study the fragmentation of cytosine (Cyt) and…

By means of layer resolved ion irradiation the mechanisms involved in the irradiation driven modifications of the exchange bias effect in NiFe/FeMn bilayers have been investigated. It is shown that not only the locations of the defects but…

Materials Science · Physics 2009-11-10 S. Poppe , J. Fassbender , B. Hillebrands

Focused ion beam irradiation of metastable Fe$_{78}$Ni$_{22}$ thin films grown on Cu(100) substrates is used to create ferromagnetic, body-centered-cubic patterns embedded into paramagnetic, face-centered-cubic surrounding. The structural…

Massive stars in their final stages of collapse radiate most of their binding energy in the form of MeV neutrinos. The recoil atoms that they produce in elastic scattering off nuclei in organic tissue create radiation damage which is highly…

Astrophysics · Physics 2009-10-28 J. I. Collar

DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function. To fully understand this molecular heterogeneity, DNA and…

Biomolecules · Quantitative Biology 2015-04-15 Adam J. M. Wollman , Helen Miller , Zhaokun Zhou , Mark C. Leake

The stability and dynamics of a double-stranded DNA (dsDNA) is affected by the preferential occupancy of small monovalent molecular ions. Small metal and molecular ions such as sodium and alkyl ammonium have crucial biological functions in…

Soft Condensed Matter · Physics 2015-08-25 Soumadwip Ghosh , Mayank Kumar Dixit , Rajarshi Chakrabarti

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

Materials Science · Physics 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

(abridged) We analyse the evolution of the fractional ionisation in a steady-state protoplanetary disc with a vertical temperature gradient and with gas-grain chemistry including surface reactions. The ionisation due to stellar X-rays,…

Astrophysics · Physics 2009-11-10 D. Semenov , D. Wiebe , Th. Henning

Purpose: To present a closed formalism calculating charged particle radiation damage induced in DNA. The formalism is valid for all types of charged particles and due to its closed nature is suited to provide fast conversion of dose to…

Medical Physics · Physics 2016-04-13 Frank Van den Heuvel

Irradiation-driven fragmentation and chemical transformations of molecular systems play a key role in nanofabrication processes where organometallic compounds break up due to the irradiation with focused particle beams. In this study,…

Chemical Physics · Physics 2023-09-06 Benjamin Andreides , Alexey V. Verkhovtsev , Juraj Fedor , Andrey V. Solov'yov

Astrophysical ionizing radiation events such as supernovae, gamma-ray bursts, and solar proton events have been recognized as a potential threat to life on Earth, primarily through depletion of stratospheric ozone and subsequent increase in…

Earth and Planetary Astrophysics · Physics 2016-01-15 Brian C. Thomas , Byron D. Goracke

Motivated by the wide ranging experimental results on the conductivity of DNA, we have investigated extraordinary configurations and chemical environments in which DNA might become a true molecular wire, perticularly from enhanced…

Soft Condensed Matter · Physics 2009-09-29 R. G. Endres , D. L. Cox , R. R. P. Singh

Monte Carlo simulations of Galactic Supernovae are carried out to study the rate of nearby events, which may have a direct effect on Earth's ecology though ionizing radiation and cosmic ray bombardment. A nearby supernova may have left a…

Astrophysics · Physics 2007-05-23 D. H. Hartmann , K. Kretschmer , R. Diehl

The transport of reactive species brought about by ions traversing tissue-like medium is analysed analytically. Secondary electrons ejected by ions are capable of ionizing other molecules; the transport of these generations of electrons is…

Biological Physics · Physics 2015-09-02 Eugene Surdutovich , Andrey V. Solov'yov

Molecular dynamics simulations have been used to study the driving force of ion irradiation induced interfacial mixing in metal bilayers in which the relative mass of the constituents is considerable. We find no apparent effect of chemical…

Materials Science · Physics 2015-06-24 P. Süle , M. Menyhárd , K. Nordlund

The theory of resonant Auger decay of atoms in a high intensity coherent X-ray pulse is presented. The theory includes the coupling between the ground state and the resonance due to an intense X-ray pulse, taking into account the decay of…

Atomic Physics · Physics 2011-05-27 Philipp V Demekhin , Lorenz S. Cederbaum