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We consider the homogenisation of a coupled Stokes flow and advection-reaction-diffusion problem in a perforated domain with an evolving microstructure of size $\varepsilon$. Reactions at the boundaries of the microscopic interfaces lead to…

Analysis of PDEs · Mathematics 2024-04-05 Markus Gahn , Malte A. Peter , Iuliu Sorin Pop , David Wiedemann

We consider a free boundary model of epithelial cell migration with logistic growth and nonlinear diffusion induced by mechanical interactions. Using numerical simulations, phase plane and perturbation analysis, we find and analyse…

Pattern Formation and Solitons · Physics 2020-10-05 Ryan J Murphy , Pascal R Buenzli , Ruth E Baker , Matthew J Simpson

Free boundaries of biofilms advancing on surfaces evolve according to conservation laws coupled with systems of partial differential equations for velocities, pressures and chemicals affecting cell behavior. Thin film approximations lead to…

Analysis of PDEs · Mathematics 2024-03-18 Ana Carpio , Gema Duro

We study flow-induced enhancement of the speed of pulsating traveling fronts for reaction-diffusion equations, and quenching of reaction by fluid flows. We prove, for periodic flows in two dimensions and any combustion-type reaction, that…

Analysis of PDEs · Mathematics 2009-05-27 Andrej Zlatos

Active motions of a biological membrane can be induced by non-thermal fluctuations that occur in the outer environment of the membrane. We discuss the dynamics of a membrane interacting hydrodynamically with an active wall that exerts…

Soft Condensed Matter · Physics 2016-05-18 Kento Yasuda , Shigeyuki Komura , Ryuichi Okamoto

Hydrodynamic interactions in a suspension of spherical particles confined between two parallel planar walls are studied under creeping-flow conditions. The many-particle friction matrix in this system is evaluated using our novel numerical…

Fluid Dynamics · Physics 2009-11-11 S. Bhattacharya , J. Blawzdziewicz , E. Wajnryb

The conventional no-slip boundary condition leads to a non-integrable stress singularity at a contact line. This is a main challenge in numerical simulations of two-phase flows with moving contact lines. We derive a two-dimensional…

Fluid Dynamics · Physics 2019-05-23 Hanna Holmgren , Gunilla Kreiss

This paper studies the intermediate time behaviour of a small random perturbation of a periodic cellular flow. Our main result shows that on time scales shorter than the diffusive time scale, the limiting behaviour of trajectories that…

Probability · Mathematics 2016-09-09 Martin Hairer , Gautam Iyer , Leonid Koralov , Alexei Novikov , Zsolt Pajor-Gyulai

A finite element approach to the elastic flow of a curve coupled with a diffusion equation on the curve is analysed. Considering the graph case, the problem is weakly formulated and approximated with continuous linear finite elements, which…

Numerical Analysis · Mathematics 2017-07-28 Paola Pozzi , Björn Stinner

We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models…

Cellular Automata and Lattice Gases · Physics 2025-01-09 Pascal R. Buenzli , Shahak Kuba , Ryan J. Murphy , Matthew J. Simpson

Near-field hydrodynamic interactions between bacteria and no-slip solid surfaces are the main mechanism underlying surface entrapment of bacteria. In this study, we employ a chiral two-body model to simulate bacterial dynamics near the…

Soft Condensed Matter · Physics 2026-02-25 Baopi Liu , Lu Chen , Haiqin Wang

Active transport such as fluid flow is sought in molecular communication to extend coverage, improve reliability, and mitigate interference. Flow models are often over-simplified, assuming one-dimensional diffusion with constant drift.…

Emerging Technologies · Computer Science 2024-10-30 Wayan Wicke , Tobias Schwering , Arman Ahmadzadeh , Vahid Jamali , Adam Noel , Robert Schober

We propose a one-way coupled model that tracks individual primary particles in a conceptually simple cellular flow setup to predict flocculation in turbulence. This computationally efficient model accounts for Stokes drag, lubrication,…

Fluid Dynamics · Physics 2020-04-22 K. Zhao , B. Vowinckel , T. -J. Hsu , T. Köllner , B. Bai , E. Meiburg

We study the kinetics of assembly of two plates of varying hydrophobicity, including cases where drying occurs and water strongly solvates the plate surfaces. The potential of mean force and molecular-scale hydrodynamics are computed from…

Soft Condensed Matter · Physics 2012-08-31 Jingyuan Li , Joseph A. Morrone , B. J. Berne

We obtain analytic expressions for the time correlation functions of a liquid of spherical particles, exact in the limit of high dimensions $d$. The derivation is long but straightforward: a dynamic virial expansion for which only the first…

Statistical Mechanics · Physics 2016-01-08 Thibaud Maimbourg , Jorge Kurchan , Francesco Zamponi

Adhesive cell-substrate interactions are crucial for cell motility and are responsible for the necessary traction that propels cells. These interactions can also change the shape of the cell, analogous to liquid droplet wetting on adhesive…

We consider numerical algorithms for the simulation of the rheology of two-dimensional vesicles suspended in a viscous Stokesian fluid. The vesicle evolution dynamics is governed by hydrodynamic and elastic forces. The elastic forces are…

Numerical Analysis · Mathematics 2015-06-17 Bryan Quaife , George Biros

We present an exact calculation of the mean first-passage time to a target on the surface of a 2D or 3D spherical domain, for a molecule alternating phases of surface diffusion on the domain boundary and phases of bulk diffusion. We…

Statistical Mechanics · Physics 2012-06-14 J. -F. Rupprecht , O. Bénichou , D. S. Grebenkov , R. Voituriez

Performing molecular dynamics simulations, we investigate the enormous slowdowns of water dynamics when approaching a glass transition or a solid interface. We show that both effects can be described on common grounds within a theoretical…

Soft Condensed Matter · Physics 2015-06-19 Felix Klameth , Michael Vogel

Eukaryotic cell motility is crucial during development, wound healing, the immune response, and cancer metastasis. Some eukaryotic cells can swim, but cells more commonly adhere to and crawl along the extracellular matrix. We study the…

Cell Behavior · Quantitative Biology 2019-09-02 Melissa H. Mai , Brian A. Camley