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Persistent homology has emerged as a popular technique for the topological simplification of big data, including biomolecular data. Multidimensional persistence bears considerable promise to bridge the gap between geometry and topology.…

Biomolecules · Quantitative Biology 2014-12-25 Kelin Xia , Guo-Wei Wei

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

The notion of data depth has long been in use to obtain robust location and scale estimates in a multivariate setting. The depth of an observation is a measure of its centrality, with respect to a data set or a distribution. The data depths…

Methodology · Statistics 2009-09-29 Sara López-Pintado , Rebecka Jornsten

This paper considers metric spaces where distances between a pair of nodes are represented by distance intervals. The goal is to study methods for the determination of hierarchical clusters, i.e., a family of nested partitions indexed by a…

Social and Information Networks · Computer Science 2016-10-17 Weiyu Huang , Alejandro Ribeiro

We develop a method for constructing tolerance bounds for functional data with random warping variability. In particular, we define a generative, probabilistic model for the amplitude and phase components of such observations, which…

Computation · Statistics 2019-07-24 J. Derek Tucker , John R. Lewis , Caleb King , Sebastian Kurtek

Manifold-learning techniques are routinely used in mining complex spatiotemporal data to extract useful, parsimonious data representations/parametrizations; these are, in turn, useful in nonlinear model identification tasks. We focus here…

Topological Data Analysis (TDA) provides a toolkit for the study of the shape of high dimensional and complex data. While operating on a space of persistence diagrams is cumbersome, persistence norms provide a simple real value measure of…

Methodology · Statistics 2023-09-26 Pawel Dlotko , Simon Rudkin

Merging the two cultures of deep and statistical learning provides insights into structured high-dimensional data. Traditional statistical modeling is still a dominant strategy for structured tabular data. Deep learning can be viewed…

Methodology · Statistics 2021-10-25 Anindya Bhadra , Jyotishka Datta , Nick Polson , Vadim Sokolov , Jianeng Xu

In the framework of model-based clustering, a model, called multi-partitions clustering, allowing several latent class variables has been proposed. This model assumes that the distribution of the observed data can be factorized into several…

Methodology · Statistics 2023-01-09 Marie du Roy de Chaumaray , Vincent Vandewalle

Multidimensional scaling (MDS) is the act of embedding proximity information about a set of $n$ objects in $d$-dimensional Euclidean space. As originally conceived by the psychometric community, MDS was concerned with embedding a fixed set…

Machine Learning · Statistics 2024-12-12 Michael W. Trosset , Carey E. Priebe

We introduce a multiscale test statistic based on local order statistics and spacings that provides simultaneous confidence statements for the existence and location of local increases and decreases of a density or a failure rate. The…

Statistics Theory · Mathematics 2008-08-07 Lutz Duembgen , Günther Walther

In cluster analysis, a common first step is to scale the data aiming to better partition them into clusters. Even though many different techniques have throughout many years been introduced to this end, it is probably fair to say that the…

Machine Learning · Computer Science 2023-05-30 Eduardo J. Aguilar , Valmir C. Barbosa

The spectra of empirical correlation matrices, constructed from multivariate data, are widely used in many areas of sciences, engineering and social sciences as a tool to understand the information contained in typically large datasets. In…

Data Analysis, Statistics and Probability · Physics 2021-08-12 Udaysinh T. Bhosale , S. Harshini Tekur , M. S. Santhanam

High-dimensional multivariate time series are challenging due to the dependent and high-dimensional nature of the data, but in many applications there is additional structure that can be exploited to reduce computing time along with…

Methodology · Statistics 2020-03-13 Michael Schweinberger , Sergii Babkin , Katherine Ensor

Multivariate geostatistics is based on modelling all covariances between all possible combinations of two or more variables at any sets of locations in a continuously indexed domain. Multivariate spatial covariance models need to be built…

Methodology · Statistics 2016-10-10 Noel Cressie , Andrew Zammit-Mangion

A well-defined distance on the parameter space is key to evaluating estimators, ensuring consistency, and building confidence sets. While there are typically standard distances to adopt in a continuous space, this is not the case for…

Statistics Theory · Mathematics 2026-02-02 Armeen Taeb , F. Richard Guo , Leonard Henckel

We consider hypothesis testing for the null hypothesis being represented as an arbitrary-shaped region in the parameter space. We compute an approximate p-value by counting how many times the null hypothesis holds in bootstrap replicates.…

Statistics Theory · Mathematics 2014-05-21 Hidetoshi Shimodaira

Block maxima methods constitute a fundamental part of the statistical toolbox in extreme value analysis. However, most of the corresponding theory is derived under the simplifying assumption that block maxima are independent observations…

Statistics Theory · Mathematics 2019-07-24 Nan Zou , Stanislav Volgushev , Axel Bücher

During the past two decades there has been a lot of interest in developing statistical depth notions that generalize the univariate concept of ranking to multivariate data. The notion of depth has also been extended to regression models and…

Methodology · Statistics 2015-08-18 Peter J. Rousseeuw , Mia Hubert

In this paper, we present a novel tolerance allocation algorithm for the assessment and control of geometric variation on system performance that is applicable to any system of partial differential equations. In particular, we parameterize…

Numerical Analysis · Mathematics 2019-04-16 Joseph Benzaken , Alireza Doostan , John A. Evans