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In this paper we enumerate $k$-noncrossing tangled-diagrams. A tangled-diagram is a labeled graph whose vertices are $1,...,n$ have degree $\le 2$, and are arranged in increasing order in a horizontal line. Its arcs are drawn in the upper…

Combinatorics · Mathematics 2008-02-26 William Y. C. Chen , Jing Qin , Christian M. Reidys , Doron Zeilberger

We introduce a novel fully convolutional neural network (FCN) architecture for predicting the secondary structure of ribonucleic acid (RNA) molecules. Interpreting RNA structures as weighted graphs, we employ deep learning to estimate the…

Biomolecules · Quantitative Biology 2024-06-07 Marc Harary , Chengxin Zhang

A topological RNA structure is derived from a diagram and its shape is obtained by collapsing the stacks of the structure into single arcs and by removing any arcs of length one. Shapes contain key topological, information and for fixed…

Combinatorics · Mathematics 2014-03-13 Fenix W. D. Huang , Christian M. Reidys

A covering array $\mathsf{CA}(N;t,k,v)$ is an $N\times k$ array with entries in $\{1, 2, \ldots , v\}$, for which every $N\times t$ subarray contains each $t$-tuple of $\{1, 2, \ldots , v\}^t$ among its rows. Covering arrays find…

Combinatorics · Mathematics 2016-05-10 Kaushik Sarkar , Charles J. Colbourn , Annalisa De Bonis , Ugo Vaccaro

Five supersymmetric scalar deformations of the AdS_5xS^5 geometry are investigated. By switching on condensates for the scalars in the N=4 multiplet with a form which preserves a subgroup of the original R-symmetry, disk and sphere…

High Energy Physics - Theory · Physics 2008-11-26 Jonathan P. Shock

In this paper we present a sampling framework for RNA structures of fixed topological genus. We introduce a novel, linear time, uniform sampling algorithm for RNA structures of fixed topological genus $g$, for arbitrary $g>0$. Furthermore…

Computational Engineering, Finance, and Science · Computer Science 2013-04-30 Fenix W. D. Huang , Markus E. Nebel , Christian M. Reidys

The contact map of a protein fold is a graph that represents the patterns of contacts in the fold. It is known that the contact map can be decomposed into stacks and queues. RNA secondary structures are special stacks in which the degree of…

Combinatorics · Mathematics 2014-06-05 William Y. C. Chen , Qiang-Hui Guo , Lisa H. Sun , Jian Wang

In this work, we consider the Combinatorial RNA Design problem, a minimal instance of the RNA design problem which aims at finding a sequence that admits a given target as its unique base pair maximizing structure. We provide complete…

Quantitative Methods · Quantitative Biology 2015-06-22 Jozef Haleš , Ján Maňuch , Yann Ponty , Ladislav Stacho

In this paper we study irreducibility in RNA structures. By RNA structure we mean RNA secondary as well as RNA pseudoknot structures. In our analysis we shall contrast random and minimum free energy (mfe) configurations. We compute various…

Biomolecules · Quantitative Biology 2009-02-24 Emma Y. Jin , Christian M. Reidys

The formation of atomic wires via pseudomorphic step-edge decoration on vicinal silicon surfaces has been analyzed for Ga on the Si(112) surface using Scanning Tunneling Microscopy and Density Functional Theory calculations. Based on a…

Materials Science · Physics 2009-11-10 C. Gonzalez , P. C. Snijders , J. Ortega , R. Perez , F. Flores , S. Rogge , H. H. Weitering

The non-orientable 4-genus of a knot $K$ in $S^{3}$, denoted $\gamma_4(K)$, measures the minimum genus of a non-orientable surface in $B^{4}$ bounded by $K$. We compute bounds for the non-orientable 4-genus of knots $T_{5, q}$ and $T_{6,…

Geometric Topology · Mathematics 2024-06-07 Megan Fairchild , Hailey Jay Garcia , Jake Murphy , Hannah Percle

The implicit signature k consists of the multiplication and the ({\omega}-1)-power. We describe a procedure to transform each {\kappa}-term over a finite alphabet A into a certain canonical form and show that different canonical forms have…

Rings and Algebras · Mathematics 2014-03-19 José Carlos Costa

Given a set $S$ of $v \ge 2$ symbols, and integers $k \ge t \ge 2$ and $N \ge 1$, an $N \times k$ array $A \in S^{N \times k}$ is an $(N; t, k, v)$-covering array if all sequences in $S^t$ appear as rows in every $N \times t$ subarray of…

Combinatorics · Mathematics 2017-03-29 Shagnik Das , Tamás Mészáros

Computational prediction of RNA structures is an important problem in computational structural biology. Studies of RNA structure formation often assume that the process starts from a fully synthesized sequence. Experimental evidence,…

Biomolecules · Quantitative Biology 2021-04-28 Vo Hong Thanh , Dani Korpela , Pekka Orponen

We study random knots, which we define as a triple of random periodic functions (where a random function is a random trigonometric series, \[f(\theta) = \sum_{k=1}^\infty a_k \cos (k \theta) +b_k (\sin k \theta),\] with $a_k, b_k$ are…

Geometric Topology · Mathematics 2016-11-08 Igor Rivin

Fix a finite ordinal n>2. We show that there exists an atomic, simple and countable representable CA_n, such that its minimal completion is outside SNr_nCA_{n+3}. Hence, for any finite k\geq 3, the variety SNr_nCA_{n+k} is not…

Logic · Mathematics 2014-08-15 Tarek Sayed Ahmed

RNA molecules are single-stranded analogues of DNA that can fold into various structures which influence their biological function within the cell. RNA structures can be modelled combinatorially in terms of a certain type of graph called an…

Combinatorics · Mathematics 2022-04-14 Vincent Moulton , Taoyang Wu

Dual graphs have been applied to model RNA secondary structures with pseudoknots, or intertwined base pairs. In previous works, a linear-time algorithm was introduced to partition dual graphs into maximally connected components called…

Biomolecules · Quantitative Biology 2021-09-09 Louis Petingi

A quantitative characterization of the relationship between molecular sequence and structure is essential to improve our understanding of how function emerges. This particular genotype-phenotype map has been often studied in the context of…

Populations and Evolution · Quantitative Biology 2017-04-20 José A. Cuesta , Susanna Manrubia

We compute the lowest moments of the nucleon's structure functions using quenched overlap fermions at two different lattice spacings. The renormalisation is done nonperturbatively in the RI'-MOM-scheme.

High Energy Physics - Lattice · Physics 2008-11-26 D. Galletly , M. Gürtler , R. Horsley , K. Koller , V. Linke , P. E. L. Rakow , C. J. Roberts , G. Schierholz , T. Streuer