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Improving health worldwide will require rigorous quantification of population-level trends in health status. However, global-level surveys are not available, forcing researchers to rely on fragmentary country-specific data of varying…

Methodology · Statistics 2014-05-20 Mariel M. Finucane , Christopher J. Paciorek , Goodarz Danaei , Majid Ezzati

Dynamic treatment regimes have been proposed to personalize treatment decisions by utilizing historical patient data, but they may not always improve on the current standard of care. It is thus meaningful to integrate the standard of care…

Applications · Statistics 2025-12-11 Johannes Hruza , Arvid Sjölander , Erin Gabriel , Samir Bhatt , Michael Sachs

Disparities in access to healthcare have been well-documented in the United States, but their effects on electronic health record (EHR) data reliability and resulting clinical models are poorly understood. Using an All of Us dataset of…

Computers and Society · Computer Science 2024-12-17 Anna Zink , Hongzhou Luan , Irene Y. Chen

Research funding agencies routinely use a proportion of their total revenues to support internal administration and marketing costs. The ratio of administration to total costs, referred to as the administration ratio, is highly variable and…

General Finance · Quantitative Finance 2016-10-07 David R Walwyn

Uncertainty can be classified as either aleatoric (intrinsic randomness) or epistemic (imperfect knowledge of parameters). The majority of frameworks assessing infectious disease risk consider only epistemic uncertainty. We only ever…

It is an important subject how deal with the symptom's data, input data, to improve the accuracy and efficiency of the diagnostic algorithm in the medical decision support systems. In this paper, we described a method for the numerical…

Computers and Society · Computer Science 2018-11-19 Won-Il Song , Taek-Jong Kim

Health exams determine a patient's health status by comparing the patient's measurement with a population reference range, a 95% interval derived from a homogeneous reference population. Similarly, most of the established relation among…

Applications · Statistics 2018-06-04 Xiaoyue Niu , Peter D. Hoff

There is tremendous interest in precision medicine as a means to improve patient outcomes by tailoring treatment to individual characteristics. An individualized treatment rule formalizes precision medicine as a map from patient information…

Machine Learning · Statistics 2020-05-28 Daniel J. Luckett , Eric B. Laber , Michael R. Kosorok

Data valuation is a class of techniques for quantitatively assessing the value of data for applications like pricing in data marketplaces. Existing data valuation methods define a value for a discrete dataset. However, in many use cases,…

Machine Learning · Computer Science 2024-10-08 Xinyi Xu , Shuaiqi Wang , Chuan-Sheng Foo , Bryan Kian Hsiang Low , Giulia Fanti

The population-wise error rate (PWER) is a type I error rate for clinical trials with multiple target populations. In such trials, a treatment is tested for its efficacy in each population. The PWER is defined as the probability that a…

Methodology · Statistics 2024-12-13 Remi Luschei , Werner Brannath

In countries that enabled patients to choose their own providers, a common problem is that the patients did not make rational decisions, and hence, fail to use healthcare resources efficiently. This might cause problems such as overwhelming…

Computers and Society · Computer Science 2020-06-25 Lichin Chen , Yu Tsao , Ji-Tian Sheu

Estimating the needs of healthcare products and inventory management are still challenging issues in hospitals nowadays. Centers are supposed to cope with tight budgets and patient satisfaction at the same time. Some issues can be tackled…

Computers and Society · Computer Science 2021-09-27 Denis Koala , Zakaria Yahouni , Gülgün Alpan , Yannick Frein

Following our previous works on the health state of a population and the related health state function we proceed in developing a method to estimate the Healthy Life Expectancy in connection to the relative impact of the Mortality Area in…

Populations and Evolution · Quantitative Biology 2012-05-15 Christos H. Skiadas , Charilaos Skiadas

America has one of the best medical systems in the world. The medical treatment care options offered by the medical system make it sophisticated. However, many American patients are not receiving health care on a regular basis, and at the…

Computers and Society · Computer Science 2022-07-05 Seongwoo Choi

Inpatient care is a large share of total health care spending, making analysis of inpatient utilization patterns an important part of understanding what drives health care spending growth. Common features of inpatient utilization measures…

Machine Learning · Statistics 2017-11-22 Christoph Kurz , Laura Hatfield

Medication adherence is a problem of widespread concern in clinical care. Poor adherence is a particular problem for patients with chronic diseases requiring long-term medication because poor adherence can result in less successful…

Methodology · Statistics 2021-04-26 Kristen B. Hunter , Mark E. Glickman , Luis F. Campos

Recent shifts in global health priorities have positioned Population Health Management (PHM) as a central area of focus. However, optimizing PHM strategies presents several challenges: managing high-dimensional patient covariates, tracking…

Optimization and Control · Mathematics 2026-04-10 Daniel Adelman , Alba V Olivares-Nadal , Miaolan Xie

Identifying optimal medical treatments to improve survival has long been a critical goal of pharmacoepidemiology. Traditionally, we use an average treatment effect measure to compare outcomes between treatment plans. However, new methods…

Recent years have seen increasing efforts to forecast infectious disease burdens, with a primary goal being to help public health workers make informed policy decisions. However, there has only been limited discussion of how predominant…

Applications · Statistics 2024-03-06 Aaron Gerding , Nicholas G. Reich , Benjamin Rogers , Evan L. Ray

Health impact simulation models are used to predict how a proposed intervention or scenario will affect public health outcomes, based on available data and knowledge of the process. The outputs of these models are uncertain due to…