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Biased sampling in molecular dynamics simulations overcomes timescale limitations and delivers free-energy landscapes, essential to understand complex atomistic phenomena. However, when applied across diverse systems and processes, biasing…

Statistical Mechanics · Physics 2026-01-14 Eline K. Kempkes , Alberto Pérez de Alba Ortíz

Distilling data into compact and interpretable analytic equations is one of the goals of science. Instead, contemporary supervised machine learning methods mostly produce unstructured and dense maps from input to output. Particularly in…

Machine Learning · Computer Science 2021-05-14 Matthias Werner , Andrej Junginger , Philipp Hennig , Georg Martius

An effective formalism for quantum constrained systems is presented which allows manageable derivations of solutions and observables, including a treatment of physical reality conditions without requiring full knowledge of the physical…

Mathematical Physics · Physics 2009-03-12 Martin Bojowald , Barbara Sandhoefer , Aureliano Skirzewski , Artur Tsobanjan

Envelope method was recently proposed as a method to reduce the dimension of responses in multivariate regressions. However, when there exists missing data, the envelope method using the complete case observations may lead to biased and…

Methodology · Statistics 2021-03-25 Linquan Ma , Lan Liu , Wei Yang

In this article the issues are discussed with the Bayesian approach, least-square fits, and most-likely fits. Trying to counter these issues, a method, based on weighted confidence, is proposed for estimating probabilities and other…

Statistics Theory · Mathematics 2017-01-26 Fetze Pijlman

With continued advances in Geographic Information Systems and related computational technologies, statisticians are often required to analyze very large spatial datasets. This has generated substantial interest over the last decade, already…

Methodology · Statistics 2019-05-14 Lu Zhang , Abhirup Datta , Sudipto Banerjee

This paper addresses challenges in flexibly modeling multimodal data that lie on constrained spaces. Such data are commonly found in spatial applications, such as climatology and criminology, where measurements are restricted to a…

Computation · Statistics 2019-12-03 Putu Ayu Sudyanti , Vinayak Rao

Model merging has attracted significant attention as a powerful paradigm for model reuse, facilitating the integration of task-specific models into a singular, versatile framework endowed with multifarious capabilities. Previous studies,…

Machine Learning · Computer Science 2025-01-03 Zhengqi Xu , Han Zheng , Jie Song , Li Sun , Mingli Song

We show how the Equation-Free approach for multi-scale computations can be exploited to systematically study the dynamics of neural interactions on a random regular connected graph under a pairwise representation perspective. Using an…

Computational Engineering, Finance, and Science · Computer Science 2015-05-13 Konstantinos G. Spiliotis , Constantinos I. Siettos

Solving large-scale optimization on-the-fly is often a difficult task for real-time computer graphics applications. To tackle this challenge, model reduction is a well-adopted technique. Despite its usefulness, model reduction often…

Graphics · Computer Science 2015-06-30 Jianbo Ye , Zhixin Yan

Matrices are said to behave as free non-commuting random variables if the action which governs their dynamics constrains only their eigenvalues, i.e. depends on traces of powers of individual matrices. The authors use recently developed…

High Energy Physics - Theory · Physics 2009-10-30 Michael Engelhardt , Shimon Levit

An algorithm is proposed, analyzed, and tested for solving continuous nonlinear-equality-constrained optimization problems where the objective and constraint functions are defined by expectations or averages over large, finite numbers of…

Optimization and Control · Mathematics 2026-05-14 Frank E. Curtis , Lingjun Guo , Daniel P. Robinson

In this paper, we propose a novel method for matrix completion under general non-uniform missing structures. By controlling an upper bound of a novel balancing error, we construct weights that can actively adjust for the non-uniformity in…

Machine Learning · Statistics 2021-06-11 Jiayi Wang , Raymond K. W. Wong , Xiaojun Mao , Kwun Chuen Gary Chan

Coupled natural systems are generally modeled at multiple abstraction levels. Both structural scale and behavioral complexity of these models are determinants in the kinds of questions that can be posed and answered. As scale and complexity…

Computational Engineering, Finance, and Science · Computer Science 2018-07-23 Hessam S. Sarjoughian , William A. Boyd , Miguel F. Acevedo

As the number of possible predictors generated by high-throughput experiments continues to increase, methods are needed to quickly screen out unimportant covariates. Model-based screening methods have been proposed and theoretically…

Methodology · Statistics 2012-05-31 Sihai D. Zhao , Yi Li

The Model-free Prediction Principle has been successfully applied to general regression problems, as well as problems involving stationary and locally stationary time series. In this paper we demonstrate how Model-Free Prediction can be…

Methodology · Statistics 2022-12-07 Srinjoy Das , Yiwen Zhang , Dimitris N. Politis

As a consequence to the hype of Grid computing, such systems have seldom been designed using formal techniques. The complexity and rapidly growing demand around Grid technologies has favour the use of classical development techniques,…

Software Engineering · Computer Science 2007-05-23 David Manset , Richard McClatchey , Flavio Oquendo , Herve Verjus

Sampling the phase space of molecular systems -- and, more generally, of complex systems effectively modeled by stochastic differential equations -- is a crucial modeling step in many fields, from protein folding to materials discovery.…

Machine Learning · Computer Science 2023-12-12 Ellis R. Crabtree , Juan M. Bello-Rivas , Andrew L. Ferguson , Ioannis G. Kevrekidis

With the rise of computers, simulation models have emerged beside the more traditional statistical and mathematical models as a third pillar for ecological analysis. Broadly speaking, a simulation model is an algorithm, typically…

Populations and Evolution · Quantitative Biology 2018-12-24 Florian Hartig

The purpose of this review paper is to present some recent results on the modeling and control of large systems of agents. We focus on particular applications where the agents are capable of independent actions instead of simply reacting to…

Optimization and Control · Mathematics 2023-02-27 Benedetto Piccoli