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Artificial Intelligence (AI) is one of the major technological advancements of this century, bearing incredible potential for users through AI-powered applications and tools in numerous domains. Being often black-box (i.e., its…

Human-Computer Interaction · Computer Science 2026-03-18 Eleonora Cappuccio , Andrea Esposito , Francesco Greco , Giuseppe Desolda , Rosa Lanzilotti , Salvatore Rinzivillo

The need for interpretable and accountable intelligent systems grows along with the prevalence of artificial intelligence applications used in everyday life. Explainable intelligent systems are designed to self-explain the reasoning behind…

Human-Computer Interaction · Computer Science 2020-08-06 Sina Mohseni , Niloofar Zarei , Eric D. Ragan

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Modern Artificial Intelligence (AI) enabled Intrusion Detection Systems (IDS) are complex black boxes. This means that a security analyst will have little to no explanation or clarification on why an IDS model made a particular prediction.…

Cryptography and Security · Computer Science 2022-07-18 Jesse Ables , Thomas Kirby , William Anderson , Sudip Mittal , Shahram Rahimi , Ioana Banicescu , Maria Seale

The impressive capabilities of deep learning models are often counterbalanced by their inherent opacity, commonly termed the "black box" problem, which impedes their widespread acceptance in high-trust domains. In response, the intersecting…

Machine Learning · Computer Science 2025-09-16 Mitali Raj

Effectively explaining decisions of black-box machine learning models is critical to responsible deployment of AI systems that rely on them. Recognizing their importance, the field of explainable AI (XAI) provides several techniques to…

Artificial Intelligence · Computer Science 2025-07-25 Yao Rong , Peizhu Qian , Vaibhav Unhelkar , Enkelejda Kasneci

The adoption of intelligent systems creates opportunities as well as challenges for medical work. On the positive side, intelligent systems have the potential to compute complex data from patients and generate automated diagnosis…

Human-Computer Interaction · Computer Science 2019-02-19 Yao Xie , Ge Gao , Xiang 'Anthony' Chen

The remarkable advancements in Deep Learning (DL) algorithms have fueled enthusiasm for using Artificial Intelligence (AI) technologies in almost every domain; however, the opaqueness of these algorithms put a question mark on their…

Machine Learning · Computer Science 2021-01-12 F. Hussain , R. Hussain , E. Hossain

The use of wearables in medicine and wellness, enabled by AI-based models, offers tremendous potential for real-time monitoring and interpretable event detection. Explainable AI (XAI) is required to assess what models have learned and build…

Signal Processing · Electrical Eng. & Systems 2026-03-16 Maurice Kuschel , Solveig Vieluf , Claus Reinsberger , Tobias Loddenkemper , Tanuj Hasija

Despite its significant benefits in enhancing the transparency and trustworthiness of artificial intelligence (AI) systems, explainable AI (XAI) has yet to reach its full potential in real-world applications. One key challenge is that XAI…

Machine Learning · Computer Science 2024-09-16 Kiana Vu , Phung Lai , Truc Nguyen

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

In recent years, black-box machine learning approaches have become a dominant modeling paradigm for knowledge extraction in remote sensing. Despite the potential benefits of uncovering the inner workings of these models with explainable AI,…

Language Models (LMs) have significantly advanced natural language processing and enabled remarkable progress across diverse domains, yet their black-box nature raises critical concerns about the interpretability of their internal…

Computation and Language · Computer Science 2025-09-29 Avash Palikhe , Zichong Wang , Zhipeng Yin , Rui Guo , Qiang Duan , Jie Yang , Wenbin Zhang

The diffusion of artificial intelligence (AI) applications in organizations and society has fueled research on explaining AI decisions. The explainable AI (xAI) field is rapidly expanding with numerous ways of extracting information and…

Human-Computer Interaction · Computer Science 2021-01-27 Julie Gerlings , Arisa Shollo , Ioanna Constantiou

Explainable Artificial Intelligence (XAI) is an emerging research field bringing transparency to highly complex and opaque machine learning (ML) models. Despite the development of a multitude of methods to explain the decisions of black-box…

Machine Learning · Computer Science 2022-03-16 Leander Weber , Sebastian Lapuschkin , Alexander Binder , Wojciech Samek

Cybersecurity vendors consistently apply AI (Artificial Intelligence) to their solutions and many cybersecurity domains can benefit from AI technology. However, black-box AI techniques present some difficulties in comprehension and adoption…

Cryptography and Security · Computer Science 2023-03-03 Carlos Mendes , Tatiane Nogueira Rios

Artificial intelligence models encounter significant challenges due to their black-box nature, particularly in safety-critical domains such as healthcare, finance, and autonomous vehicles. Explainable Artificial Intelligence (XAI) addresses…

Artificial Intelligence · Computer Science 2025-03-14 Melkamu Mersha , Khang Lam , Joseph Wood , Ali AlShami , Jugal Kalita

Given the sheer volume of surgical procedures and the significant rate of postoperative fatalities, assessing and managing surgical complications has become a critical public health concern. Existing artificial intelligence (AI) tools for…

Here, we address the problem of Independent Subspace Analysis (ISA). We develop a technique that (i) builds upon joint decorrelation for a set of functions, (ii) can be related to kernel based techniques, (iii) can be interpreted as a…

Statistics Theory · Mathematics 2012-01-04 Zoltan Szabo , Andras Lorincz

Context. Inferring spectral parameters from X-ray data is one of the cornerstones of high-energy astrophysics, and is achieved using software stacks that have been developed over the last twenty years and more. However, as models get more…

Instrumentation and Methods for Astrophysics · Physics 2024-10-23 Simon Dupourqué , Didier Barret , Camille M. Diez , Sébastien Guillot , Erwan Quintin