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Clinical diagnosis requires answers that are accurate, verifiable, and explicitly grounded in official guidelines. While large language models excel at natural language processing, their tendency to hallucinate undermines their utility in…

Artificial Intelligence · Computer Science 2026-05-29 Navapat Nananukul , Mayank Kejriwal

Conformance checking is a process mining technique that allows verifying the conformance of process instances to a given model. Thus, this technique is predestined to be used in the medical context for the comparison of treatment cases with…

Artificial Intelligence · Computer Science 2022-09-21 Joscha Grüger , Tobias Geyer , Martin Kuhn , Stefan Braun , Ralph Bergmann

Clinical trials are critical for drug development. Constructing the appropriate eligibility criteria (i.e., the inclusion/exclusion criteria for patient recruitment) is essential for the trial's success. Proper design of clinical trial…

Computation and Language · Computer Science 2023-10-10 Zifeng Wang , Cao Xiao , Jimeng Sun

Diagnostic imaging studies are an increasingly important component of the workup and management of acutely presenting patients. However, ordering appropriate imaging studies according to evidence-based medical guidelines is a challenging…

Machine Learning · Computer Science 2025-08-06 Michael S. Yao , Allison Chae , Charles E. Kahn , Walter R. Witschey , James C. Gee , Hersh Sagreiya , Osbert Bastani

Automatically reasoning with conflicting generic clinical guidelines is a burning issue in patient-centric medical reasoning where patient-specific conditions and goals need to be taken into account. It is even more challenging in the…

Artificial Intelligence · Computer Science 2019-02-21 Kristijonas Čyras , Tiago Oliveira

Clinical evidence underpins informed healthcare decisions, yet integrating it into real-time practice remains challenging due to intensive workloads, complex procedures, and time constraints. This study presents Quicker, an LLM-powered…

Two main approaches for evaluating the quality of machine-generated rationales are: 1) using human rationales as a gold standard; and 2) automated metrics based on how rationales affect model behavior. An open question, however, is how…

Computation and Language · Computer Science 2020-10-13 Samuel Carton , Anirudh Rathore , Chenhao Tan

Improving effectiveness and safety of patient care is an ultimate objective for medical cyber-physical systems. A recent study shows that the patients' death rate can be reduced by computerizing medical guidelines. Most existing medical…

Software Engineering · Computer Science 2018-11-21 Chunhui Guo , Zhicheng Fu , Zhenyu Zhang , Shangping Ren , Lui Sha

Diabetes Mellitus is a metabolic disorder which may result in severe and potentially fatal complications if not well-treated and monitored. In this study, a quantitative analysis of the data collected using CGM (Continuous Glucose…

Quantitative Methods · Quantitative Biology 2023-08-15 Giulia Elena Aliffi , Giovanni Nastasi , Vittorio Romano , Dario Pitocco , Alessandro Rizzi , Elvin J. Moore , Andrea De Gaetano

Evaluating automatically generated text is generally hard due to the inherently subjective nature of many aspects of the output quality. This difficulty is compounded in automatic consultation note generation by differing opinions between…

Computation and Language · Computer Science 2022-11-18 Aleksandar Savkov , Francesco Moramarco , Alex Papadopoulos Korfiatis , Mark Perera , Anya Belz , Ehud Reiter

Clinical guidance systems have been widely adopted to help medical staffs to avoid preventable medical errors such as delay in diagnosis, treatment or untended deviations from best practice guidelines. However, because patient condition…

Computers and Society · Computer Science 2016-10-24 Maryam Rahmaniheris , Yu Jiang , Lui Sha

In this work, we propose Oph-Guid-RAG, a multimodal visual RAG system for ophthalmology clinical question answering and decision support. We treat each guideline page as an independent evidence unit and directly retrieve page images,…

Artificial Intelligence · Computer Science 2026-03-24 Shuying Chen , Sen Cui , Zhong Cao

The direct measurement of quality is difficult because there is no way we can measure quality factors. For measuring these factors, we have to express them in terms of metrics or models. Researchers have developed quality models that…

Software Engineering · Computer Science 2010-04-28 Devpriya Soni , Namita Shrivastava , M. Kumar

It has been suggested that bibliometric analysis of different document types may reveal new aspects of research performance. In medical research a number of study types play different roles in the research process and it has been shown,…

Digital Libraries · Computer Science 2013-01-25 Jens Peter Andersen

Reporting quality is an important topic in clinical trial research articles, as it can impact clinical decisions. In this article, we test the ability of large language models to assess the reporting quality of this type of article using…

Computation and Language · Computer Science 2025-10-07 Mathieu Laï-king , Patrick Paroubek

Explanations shed light on a machine learning model's rationales and can aid in identifying deficiencies in its reasoning process. Explanation generation models are typically trained in a supervised way given human explanations. When such…

Machine Learning · Computer Science 2021-09-09 Pepa Atanasova , Jakob Grue Simonsen , Christina Lioma , Isabelle Augenstein

Coding of unstructured clinical free-text to produce interoperable structured data is essential to improve direct care, support clinical communication and to enable clinical research.However, manual clinical coding is difficult and time…

Randomized controlled trials (RCTs) represent the paramount evidence of clinical medicine. Using machines to interpret the massive amount of RCTs has the potential of aiding clinical decision-making. We propose a RCT conclusion generation…

Computation and Language · Computer Science 2019-10-04 Alexander Te-Wei Shieh , Yung-Sung Chuang , Shang-Yu Su , Yun-Nung Chen

Medical dialogue systems have attracted significant attention for their potential to act as medical assistants. Enabling these medical systems to emulate clinicians' diagnostic reasoning process has been the long-standing research focus.…

Computation and Language · Computer Science 2024-06-21 Kaishuai Xu , Yi Cheng , Wenjun Hou , Qiaoyu Tan , Wenjie Li

Model checking and automated theorem proving are two pillars of formal methods. This paper investigates model checking from an automated theorem proving perspective, aiming at combining the expressiveness of automated theorem proving and…

Logic in Computer Science · Computer Science 2017-10-03 Ying Jiang , Jian Liu , Gilles Dowek , Kailiang Ji
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