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Dynamic treatment regimes (DTRs) formalize medical decision-making as a sequence of rules for different stages, mapping patient-level information to recommended treatments. In practice, estimating an optimal DTR using observational data…

Methodology · Statistics 2024-12-11 Jian Sun , Bo Fu , Li Su

We consider a trait-structured population subject to mutation, birth and competition of logistic type, where the number of coexisting types may fluctuate. Applying a limit of rare mutations to this population while keeping the population…

Probability · Mathematics 2011-12-05 Nicolas Champagnat , Amaury Lambert

Quasispecies theory provides the conceptual and theoretical bases for describing the dynamics of biological information of replicators subject to large mutation rates. This theory, initially conceived within the framework of prebiotic…

Populations and Evolution · Quantitative Biology 2025-06-26 Edward A. Turner , Francisco Crespo , Josep Sardanyés , Nolbert Morales

We consider a D-dimensional fluid membrane in a D+1-dimensional embedding space, subject to quantum fluctuations. The corresponding action is invariant under coordinate transformations and depends only on the shape of the membrane and its…

Soft Condensed Matter · Physics 2008-11-26 Georg Foltin

The mean size of exponentially dividing E. coli cells cultured in different nutrient conditions is known to depend on the mean growth rate only. However, the joint fluctuations relating cell size, doubling time and individual growth rate…

A central problem in biology is to understand how organisms evolve and adapt to their environment by acquiring variations in the observable characteristics or traits of species across the tree of life. With the growing availability of…

Simulating quantum imaginary-time evolution (QITE) is a major promise of quantum computation. However, the known algorithms are either probabilistic (repeat until success) with impractically small success probabilities or coherent (quantum…

Quantum Physics · Physics 2023-11-02 Thais de Lima Silva , Márcio M. Taddei , Stefano Carrazza , Leandro Aolita

We investigate the dynamics of a quantum system subjected to a time-dependent and conditional resetting protocol. Namely, we ask: what happens when the unitary evolution of the system is repeatedly interrupted at random time instants with…

Statistical Mechanics · Physics 2023-12-20 Anish Acharya , Shamik Gupta

The capacity of cells and organisms to respond to challenging conditions in a repeatable manner is limited by a finite repertoire of pre-evolved adaptive responses. Beyond this capacity, cells can use exploratory dynamics to cope with a…

Molecular Networks · Quantitative Biology 2017-07-05 Hallel I. Schreier , Yoav Soen , Naama Brenner

We develop a consistent perturbation theory in quantum fluctuations around the classical evolution of a system of interacting bosons. The zero order approximation gives the classical Gross-Pitaevskii equations. In the next order we recover…

Statistical Mechanics · Physics 2007-05-23 Anatoli Polkovnikov

A quantitatively reliable theoretical description of the dynamics of fluctuations in non-equilibrium is indispensable in the experimental search for the QCD critical point by means of ultra-relativistic heavy-ion collisions. In this work we…

Nuclear Theory · Physics 2019-06-26 Marlene Nahrgang , Marcus Bluhm , Thomas Schaefer , Steffen A. Bass

Computerized adaptive tests (CATs) play a crucial role in educational assessment and diagnostic screening in behavioral health. Unlike traditional linear tests that administer a fixed set of pre-assembled items, CATs adaptively tailor the…

Methodology · Statistics 2026-05-11 Jiguang Li , Robert Gibbons , Veronika Rockova

Rapidly evolving pathogens like influenza viruses can persist by accumulating antigenic novelty fast enough to evade the adaptive immunity of the host population, yet without continuous accumulation of genetic diversity. This dynamical…

Populations and Evolution · Quantitative Biology 2018-10-30 Le Yan , Richard Neher , Boris I Shraiman

An integro-differential model for evolutionary dynamics with mutations is investigated by improving the understanding of its behavior using numerical simulations. The proposed numerical approach can handle also density dependent fitness,…

Populations and Evolution · Quantitative Biology 2020-01-27 A. L. Amadori , M. Briani , R. Natalini

We analyze the dynamics of entanglement entropy in a generic quantum many-body open system from the perspective of quantum information and error corrections. We introduce a random unitary circuit model with intermittent projective…

Quantum Physics · Physics 2020-07-17 Soonwon Choi , Yimu Bao , Xiao-Liang Qi , Ehud Altman

The fluctuation behavior of triple quantum dots (TQDs) has, so far, largely focused on current cumulants in the long-time limit via full counting statistics. Given that (TQDs) are non-trivial open quantum systems with many interesting…

Mesoscale and Nanoscale Physics · Physics 2021-11-10 Samuel L. Rudge , Daniel S. Kosov

Variational quantum algorithms have been proposed to solve static and dynamic problems of closed many-body quantum systems. Here we investigate variational quantum simulation of three general types of tasks---generalised time evolution with…

Quantum Physics · Physics 2020-07-01 Suguru Endo , Jinzhao Sun , Ying Li , Simon Benjamin , Xiao Yuan

Semiconductor nano-crystals, known as quantum dots (QDs), have attracted significant attention for their unique fluorescence properties. Under continuous excitation, QDs emit photons with intricate intensity fluctuation: the intensity of…

Applied Physics · Physics 2025-04-28 Xin Yang , Hawi Nyiera , Yonglei Sun , Jing Zhao , Kun Chen

Differential evolution (DE) is a population based evolutionary algorithm widely used for solving multidimensional global optimization problems over continuous spaces. However, the design of its operators makes it unsuitable for many…

Neural and Evolutionary Computing · Computer Science 2011-05-17 Ashish Ranjan Hota , Ankit Pat

The effect of a change of noise amplitudes in overdamped diffusive systems is linked to their unperturbed behavior by means of a nonequilibrium fluctuation-response relation. This formula holds also for systems with state-independent…

Statistical Mechanics · Physics 2017-06-13 Cem Yolcu , Antoine Bérut , Gianmaria Falasco , Artyom Petrosyan , Sergio Ciliberto , Marco Baiesi