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In stable environments, cell size fluctuations are thought to be governed by simple physical principles, as suggested by recent findings of scaling properties. Here, by developing a microfluidic device and using E. coli, we investigate the…

Cell Behavior · Quantitative Biology 2021-11-12 Takuro Shimaya , Reiko Okura , Yuichi Wakamoto , Kazumasa A. Takeuchi

It has experimentally been found by Lampo et al. [Biophys. J. 112, 532 (2017)] that, for two different types of cell, the distribution of the diffusivities of RNA-protein particles over cytoplasm obeys an exponential law. Then, an…

Biological Physics · Physics 2019-08-02 Yuichi Itto

The multi-population replicator dynamics (RD) can be considered a dynamic approach to the study of multi-player games, where it was shown to be related to Cross' learning, as well as of systems of coevolving populations. However, not all of…

Populations and Evolution · Quantitative Biology 2020-07-01 Johann Bauer , Mark Broom , Eduardo Alonso

Ecological and evolutionary dynamics have been historically regarded as unfolding at broadly separated timescales. However, these two types of processes are nowadays well documented to much more tightly than traditionally assumed,…

Populations and Evolution · Quantitative Biology 2021-11-17 José Camacho Mateu , Matteo Sireci , Miguel A. Muñoz

Imaginary-time evolution is fundamental for analyzing quantum many-body systems, yet classical simulation requires exponentially growing resources in both system size and evolution time. While quantum approaches reduce the system-size…

Quantum Physics · Physics 2025-12-12 Lei Zhang , Jizhe Lai , Xian Wu , Xin Wang

The proper functioning of multicellular organisms requires the robust establishment of precise proportions between distinct cell-types. This developmental differentiation process typically involves intracellular regulatory and stochastic…

Cell Behavior · Quantitative Biology 2016-06-22 Benjamin Pfeuty , Kunihiko Kaneko

We propose an adaptive quantum algorithm to prepare accurate variational time evolved wave functions. The method is based on the projected Variational Quantum Dynamics (pVQD) algorithm, that performs a global optimization with linear…

Quantum Physics · Physics 2025-02-20 David Linteau , Stefano Barison , Netanel Lindner , Giuseppe Carleo

Despite the wealth of empirical and theoretical studies, the origin and maintenance of cooperation is still an evolutionary riddle. In this context, ecological life-history traits which affect the efficiency of selection may play a role,…

Populations and Evolution · Quantitative Biology 2019-04-16 Thibaut Sellinger , Johannes Müller , Volker Hösel , Aurélien Tellier

We consider the dynamics of the disordered trap model, which is known to be completely out-of-equilibrium and to present strong localization effects in its aging phase. We are interested into the influence of an external force, when it is…

Condensed Matter · Physics 2009-11-10 Cecile Monthus

With a view to connecting random mutation on the molecular level to punctuated equilibrium behavior on the phenotype level, we propose a new model for biological evolution, which incorporates random mutation and natural selection. In this…

Condensed Matter · Physics 2009-10-28 M. Y. Choi , H. Y. Lee , D. Kim , S. H. Park

Quantum error correction will be essential for realizing the full potential of large-scale quantum information processing devices. Fundamental to its experimental realization is the repetitive detection of errors via projective measurements…

Nutrient limitation is one of the most common triggers of antibiotic tolerance and persistence. Here, we present two microfluidic setups to study how spatial and temporal variation in nutrient availability lead to increased survival of…

Quantitative Methods · Quantitative Biology 2020-10-29 Stefany Moreno-Gámez , Alma Dal Co , Simon van Vliet , Martin Ackermann

Feature interaction selection is a fundamental problem in commercial recommender systems. Most approaches equally enumerate all features and interactions by the same pre-defined operation under expert guidance. Their recommendation is…

Artificial Intelligence · Computer Science 2024-05-30 Runlong Yu , Qixiang Shao , Qi Liu , Huan Liu , Enhong Chen

Quantitative characterization of bacterial growth has gathered substantial attention since Monod's pioneering study. Theoretical and experimental work has uncovered several laws for describing the log growth phase, in which the number of…

Biological Physics · Physics 2017-07-05 Yusuke Himeoka , Kunihiko Kaneko

Networked dynamical systems, i.e., systems of dynamical units coupled via nontrivial interaction topologies, constitute models of broad classes of complex systems, ranging from gene regulatory and metabolic circuits in our cells to…

Adaptation and Self-Organizing Systems · Physics 2024-03-12 Xiaozhu Zhang , Marc Timme

Considerable theoretical and experimental efforts have been devoted to the quench dynamics, in particular, the dynamical quantum phase transition (DQPT) and the steady-state transition. These developments have motivated us to study the…

Quantum Gases · Physics 2020-03-30 Pei Wang , Gao Xianlong

Fluctuations of cell state, e.g., abundances of some proteins, have attracted much attention both theoretically and experimentally. The distribution of such state over cells, however, is not only a result of intracellular stochastic…

Biological Physics · Physics 2007-05-23 Katsuhiko Sato , Kunihiko Kaneko

Variational quantum circuits have arisen as an important method in quantum computing. A crucial step of it is parameter optimization, which is typically tackled through gradient-descent techniques. We advantageously explore instead the use…

Quantum Physics · Physics 2024-12-24 Vignesh Anantharamakrishnan , Márcio M. Taddei

Quantum defect embedding theory (QDET) is a many-body embedding method designed to describe condensed systems with correlated electrons localized within a given region of space, for example spin defects in semiconductors and insulators.…

Materials Science · Physics 2025-08-28 Siyuan Chen , Victor Wen-zhe Yu , Yu Jin , Marco Govoni , Giulia Galli

We present a modified water-vegetation model to investigate the mechanistic relationship between infiltration-soil moisture feedback and vegetation pattern in arid/semi-arid ecosystems. Employing Turing pattern formation theory, we drive…

Dynamical Systems · Mathematics 2025-08-05 Juan Yan , Xiaoli Wang , Guohong Zhang , Yuan Yuan